Relationship between susceptibility to daptomycin in vitro and activity in vivo in a rabbit model of aortic valve endocarditis

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 4, 2009, Pages 1463-1467

  Chambers, H F ^a   Basuino, L ^a   Diep, B A ^a   Steenbergen, J ^b   Zhang, S ^b   Tattevin, P ^c   Aider, J ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CUBIST PHARMACEUTICALS INC   (United States)

^c PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^d BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DAPTOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; AORTIC VALVE ENDOCARDITIS; ARTICLE; BACTERIAL ENDOCARDITIS; COLONY FORMING UNIT; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG EFFICACY; ENDOCARDIUM; KIDNEY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; SINGLE DRUG DOSE; SPLEEN; STAPHYLOCOCCUS AUREUS; SURVIVAL;

ANIMALS; ANTI-BACTERIAL AGENTS; AORTIC VALVE; AREA UNDER CURVE; DAPTOMYCIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCARDITIS, BACTERIAL; HEART VALVE DISEASES; MICROBIAL SENSITIVITY TESTS; RABBITS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 65649086112     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01307-08     Document Type: Article

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