Daptomycin pharmacokinetics and safety following administration of escalating doses once daily to healthy subjects

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 4, 2003, Pages 1318-1323

  Dvorchik, Barry H ^a   Brazier, David ^a   DeBruin, Michael F ^a   Arbeit, Robert D ^a  

^a CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DAPTOMYCIN; METICILLIN; VANCOMYCIN;

ADULT; ANTIBIOTIC RESISTANCE; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ERUPTION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG TOLERABILITY; DRUG URINE LEVEL; FEMALE; GASTROINTESTINAL SYMPTOM; GRAM POSITIVE BACTERIUM; HEADACHE; HUMAN; INFECTION; INSOMNIA; LUNG TOXICITY; MALE; MUSCLE WEAKNESS; NEPHROTOXICITY; NEUROTOXICITY; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SIDE EFFECT; SKIN TOXICITY;

ADULT; ANTI-BACTERIAL AGENTS; CREATINE KINASE; DAPTOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE;

EID: 0037378761     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.4.1318-1323.2003     Document Type: Article

References (14)

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