Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells

Respiratory Research

Volumn 10, Issue , 2009, Pages

  Kawanami, Yukiko ^a   Morimoto, Yasuo ^a   Kim, Heungnam ^a   Nakamura, Takehiro ^a   Machida, Kazuhiko ^a   Kido, Takashi ^a   Asonuma, Etsuko ^a   Yatera, Kazuhiro ^a   Yoshii, Chiharu ^a   Kido, Masamitsu ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; CYCLINE; DNA; NEUROPEPTIDE; PROTEIN P42; PROTEIN P44; RECOMBINANT CALCITONIN GENE RELATED PEPTIDE; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; CALCITONIN GENE RELATED PEPTIDE (8 37); CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE-RELATED PEPTIDE (8-37); MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRILE; PEPTIDE FRAGMENT; PROTEIN KINASE INHIBITOR; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO CULTURE; LUNG ALVEOLUS CELL; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING; ADENOVIRUS; ANIMAL; DNA REPLICATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; LUNG ALVEOLUS; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TIME; TUMOR CELL LINE; WISTAR RAT;

ADENOVIRIDAE; ANIMALS; BUTADIENES; CALCITONIN GENE-RELATED PEPTIDE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA REPLICATION; EPITHELIAL CELLS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN KINASE INHIBITORS; PULMONARY ALVEOLI; RATS; RATS, WISTAR; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 65649086015     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-10-8     Document Type: Article

References (28)

1. Goodman EC, Iversen LL. Calcitonin gene-related peptide: novel neuropeptide. Life Sci 1986, 38(24):2169-2178. 10.1016/0024-3205(86)90568-0, 2423836.
2. Komatsu T, Yamamoto M, Shimokata K, Nagura H. Distribution of substance P-immunoreactive and calcitonin gene-related peptide-immunoreactive nerves in normal human lungs. Int Arch Allergy Appl Immunol 1991, 95(1):23-28.
3. Brain SD, Williams TJ, Tippins JR, Morris HR, MacIntyre I. Calcitonin gene-related peptide is a potent vasodilator. Nature 1985, 313(5997):54-56. 10.1038/313054a0, 3917554.
4. Cadieux A, Monast NP, Pomerleau F, Fournier A, Lanoue C. Bronchoprotector properties of calcitonin gene-related peptide in guinea pig and human airways. Effect of pulmonary inflammation. Am J Respir Crit Care Med 1999, 159(1):235-243.
5. Nong YH, Titus RG, Ribeiro JM, Remold HG. Peptides encoded by the calcitonin gene inhibit macrophage function. J Immunol 1989, 143(1):45-49.
6. Aoki-Nagase T, Nagase T, Oh-Hashi Y, Shindo T, Kurihara Y, Yamaguchi Y, Yamamoto H, Tomita T, Ohga E, Nagai R, Kurihara H, Ouchi Y. Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice. Am J Physiol Lung Cell Mol Physiol 2002, 283(5):L963-970.
7. Haegerstrand A, Dalsgaard CJ, Jonzon B, Larsson O, Nilsson J. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA 1990, 87(9):3299-3303. 53887, 2159144, 10.1073/pnas.87.9.3299.
8. White SR, Hershenson MB, Sigrist KS, Zimmermann A, Solway J. Proliferation of guinea pig tracheal epithelial cells induced by calcitonin gene-related peptide. Am J Respir Cell Mol Biol 1993, 8(6):592-596.
9. Sanghavi JN, Rabe KF, Kim JS, Magnussen H, Leff AR, White SR. Migration of human and guinea pig airway epithelial cells in response to calcitonin gene-related peptide. Am J Respir Cell Mol Biol 1994, 11(2):181-187.
10. Kishi H, Mishima HK, Sakamoto I, Yamashita U. Stimulation of retinal pigment epithelial cell growth by neuropeptides in vitro. Curr Eye Res 1996, 15(7):708-713. 10.3109/02713689609003452, 8670777.
11. Head GM, Mentlein R, von Patay B, Downing JE, Kendall MD. Neuropeptides exert direct effects on rat thymic epithelial cells in culture. Dev Immunol 1998, 6(1-2):95-104. 2276004, 9716910.
12. Stevens TP, McBride JT, Peake JL, Pinkerton KE, Stripp BR. Cell proliferation contributes to PNEC hyperplasia after acute airway injury. Am J Physiol 1997, 272(3 Pt 1):L486-493.
13. Morimoto Y, Ogami A, Nagatomo H, Hirohashi M, Oyabu T, Kuroda K, Kawanami Y, Murakami M, Myojo T, Higashi T, Tanaka I. Calcitonin gene-related peptide (CGRP) as hazard marker for lung injury induced by dusts. Inhal Toxicol 2007, 19(3):283-289. 10.1080/08958370601069364, 17365031.
14. Okajima K, Harada N. Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications. Curr Med Chem 2006, 13(19):2241-2251. 10.2174/092986706777935131, 16918352.
15. Harrison NK, Dawes KE, Kwon OJ, Barnes PJ, Laurent GJ, Chung KF. Effects of neuropeptides on human lung fibroblast proliferation and chemotaxis. Am J Physiol 1995, 268(2 Pt 1):L278-283.
16. Li Y, Fiscus RR, Wu J, Yang L, Wang X. The antiproliferative effects of calcitonin gene-related peptide in different passages of cultured vascular smooth muscle cells. Neuropeptides 1997, 31(5):503-509. 10.1016/S0143-4179(97)90046-9, 9413029.
17. Shiratori M, Michalopoulos G, Shinozuka H, Singh G, Ogasawara H, Katyal SL. Hepatocyte growth factor stimulates DNA synthesis in alveolar epithelial type II cells in vitro. Am J Respir Cell Mol Biol 1995, 12(2):171-180.
18. Morikawa O, Walker TA, Nielsen LD, Pan T, Cook JL, Mason RJ. Effect of adenovector-mediated gene transfer of keratinocyte growth factor on the proliferation of alveolar type II cells in vitro and in vivo. Am J Respir Cell Mol Biol 2000, 23(5):626-635.
19. Ryan RM, Mineo-Kuhn MM, Kramer CM, Finkelstein JN. Growth factors alter neonatal type II alveolar epithelial cell proliferation. Am J Physiol 1994, 266(1 Pt 1):L17-22.
20. Panos RJ, Bak PM, Simonet WS, Rubin JS, Smith LJ. Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats. J Clin Invest 1995, 96(4):2026-2033. 185841, 7560096, 10.1172/JCI118250.
21. Panos RJ, Rubin JS, Csaky KG, Aaronson SA, Mason RJ. Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium. J Clin Invest 1993, 92(2):969-977. 294937, 7688769, 10.1172/JCI116673.
22. Panos RJ, Patel R, Bak PM. Intratracheal administration of hepatocyte growth factor/scatter factor stimulates rat alveolar type II cell proliferation in vivo. Am J Respir Cell Mol Biol 1996, 15(5):574-581.
23. Wang W, Jia L, Wang T, Sun W, Wu S, Wang X. Endogenous calcitonin gene-related peptide protects human alveolar epithelial cells through protein kinase Cepsilon and heat shock protein. J Biol Chem 2005, 280(21):20325-20330. 10.1074/jbc.M413864200, 15784626.
24. Shimosegawa T, Said SI. Pulmonary calcitonin gene-related peptide immunoreactivity: nerve-endocrine cell interrelationships. Am J Respir Cell Mol Biol 1991, 4(2):126-134.
25. Li W, Hou L, Hua Z, Wang X. Interleukin-1beta induces beta-calcitonin gene-related peptide secretion in human type II alveolar epithelial cells. Faseb J 2004, 18(13):1603-1605.
26. Thrane EV, Schwarze PE, Thoresen GH, Lag M, Refsnes M. Persistent versus transient map kinase (ERK) activation in the proliferation of lung epithelial type 2 cells. Exp Lung Res 2001, 27(4):387-400. 10.1080/019021401750193638, 11400863.
27. Portnoy J, Curran-Everett D, Mason RJ. Keratinocyte growth factor stimulates alveolar type II cell proliferation through the extracellular signal-regulated kinase and phosphatidylinositol 3-OH kinase pathways. Am J Respir Cell Mol Biol 2004, 30(6):901-907. 10.1165/rcmb.2003-0406OC, 14742297.
28. Harada N, Okajima K, Kurihara H, Nakagata N. Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-1, thereby reducing reperfusion-induced apoptosis in mice. Neuropharmacology 2007, 52(5):1303-11. 10.1016/j.neuropharm.2007.01.016, 17360009.