The effect of Echinacea purpurea on the morphology, angiogenic activity and vascular endothelial growth factor (VEGF) concentration of murine L-1 sarcoma tumors

Central-European Journal of Immunology

Volumn 34, Issue 1, 2009, Pages 38-41

  Wasiutyński, Aleksander ^a   Bałan, Barbara J ^a   Skopińska Rózewska, Ewa ^a   Siwicki, Andrzej K ^b   Skurzak, Henryk ^c   Chorostowska Wynimko, Joanna ^d   Sommer, Ewa ^a   Mazurkiewicz, Michał ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

^c INSTITUTE OF ONCOLOGY   (Poland)

^d NATIONAL TUBERCULOSIS AND LUNG DISEASES RESEARCH INSTITUTE   (Poland)

Author keywords

Echinacea purpurea; L 1 sarcoma; Mice

Indexed keywords

ECHINACEA PURPUREA EXTRACT; ECHINAPUR; IMMUNAL FORTE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; SARCOMA; SARCOMA CELL; TUMOR VASCULARIZATION; TUMOR VOLUME;

EID: 65549169607     PISSN: 14263912     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Skopińska-Rózewska E, Strzelecka H, Wasiutyński A et al. (2008): Aqueous and hydro-alcoholic extracts of Echinacea purpurea (L) Moench as traditional herbal remedies with immunotropic activity. Centr Eur J Immunol 33: 78-82.
2. Skopińska- Rózewska E, Sokolnicka I, Radomska-Leśniewska D et al. (2003): The in vivo effect of Echinacea purpurea succus on various functions of human blood leukocytes. Centr Eur J Immunol 28: 126-130.
3. Skopińska-Rózewska E, Furmanowa M, Guzewska J et al. (2002): The effect of Centella asiatica, Echinacea purpurea and Melaleuca alternifolia on cellular immunity in mice. Centr Eur J Immunol 27: 142-148.
4. Sokolnicka I, Skopińska-Rózewska E, Strzelecka H et al. (2001): Adaptacja testów biologicznych do oceny aktywności preparatów jezαcowki purpurowej (Echinacea purpurea). I. Badania in vivo. Terapia 9: 38-42.
5. Sawicka T, Rogala E, Strzelecka H et al. (2001): As above. II. Badania in vitro. Terapia 9: 43-46.
6. Mierzwińska-Nastalska E, Demkow U, Siwicki AK et al. (2005): The effect of Echinacea purpurea extract Echinapur on the angiogenic and chemokinetic activity of human leukocytes. Pol J Environm Studies 14 (Suppl II): 639-642.
7. Rogala E, Skopińska-Rózewska E, Wasiutyński A et al. (2008): Echinacea purpurea diminishes neovascular reaction induced in mice skin by human cancer cells and stimulates non-specific cellular immunity in humans. Centr Eur J Immunol 33: 127-130.
8. Melchart D, Clemm C, Weber B et al. (2002): Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy - a pilot study. Phytother Res 16: 138-142.
9. Chicca A, Adinolfi B, Martinotti E et al. (2007): Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines. J Ethnopharmacol 110: 148-153.
10. Cao Y, Cao R, Brakenhelm E (2002): Anti-angiogenic mechanism of diet-derived polyphenols. J Nutr Biochem 13: 380-390.
11. Kim MH (2003): Flavonoids inhibit VEGF/bFGF - induced angiogenesis in vitro by inhibiting the matrix-degrading proteases. J Cell Biochem 89: 529-538.
12. Carlo GD, Nuzzo I, Capasso R et al. (2003): Modulation of apoptosis in mice treated with Echinacea and St. John's wort. Pharmacol Res 48: 273-277.
13. Skopińska-Rózewska E, Skurzak H, Wasiutyński A et al. (2007): Sarcoma L-1 in mice as a model for the study of experimental angiogenesis. Centr Eur J Immunol 32: 77-83.
14. Bałan BJ, Słotwiński R (2008): VEGF and tumor angiogenesis. Centr Eur J Immunol 33: 232-236.
15. Skopiński P, Skopińska-Rózewska E, Sommer E et al. (2005): The effect of some diet-derived angiogenesis inhibitors and sulindac sulfone on the ability of VEGF, bFGF, and IL-18 to induce cutaneous neo-vascular response in mice. Pol J Environ Studies 14 (Suppl II): 325-329.
16. Bałan BJ, Skopińska-Rózewska E, Barcz E et al. (1999): The effect of selected phenolic acids on angiogenic activity of ovarian cancer cells. Onkol Pol 2: 203-208.
17. Bany J, Skopińska-Rózewska E, Chorostowska-Wynimko J et al. (2004): The effect of complex herbal remedy on the angiogenic activity of L-1 sarcoma cells, L-1 sarcoma tumor growth and on the bacterial infection in mice. Centr Eur J Immunol 29: 1-6.