Half body irradiation of patients with multiple bone metastases: A phase II trial

Acta Oncologica

Volumn 48, Issue 4, 2009, Pages 556-561

  Berg, Randi S ^a   Yilmaz, Mette K ^a   Høyer, Morten ^b   Keldsen, Nina ^c   Nielsen, Ole S ^b   Ewertz, Marianne ^d  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c HERNING HOSPITAL   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANALGESIA; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER PAIN; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; FATIGUE; FEMALE; FOLLOW UP; HALF BODY IRRADIATION; HUMAN; LUNG CANCER; LUNG DISEASE; MALE; MEDICAL RECORD; PRIORITY JOURNAL; PROSTATE CANCER; QUALITY OF LIFE; RADIATION DOSE; VOMITING; BONE TUMOR; LUNG; METASTASIS; METHODOLOGY; MIDDLE AGED; PAIN; PATHOLOGY; PHASE 2 CLINICAL TRIAL; PROSTATE TUMOR; QUESTIONNAIRE; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOTHERAPY; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; BONE NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FOLLOW-UP STUDIES; HEMIBODY IRRADIATION; HUMANS; LUNG; MALE; MIDDLE AGED; PAIN; PROSTATIC NEOPLASMS; QUALITY OF LIFE; QUESTIONNAIRES; TREATMENT OUTCOME;

EID: 65549152807     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.1080/02841860802488128     Document Type: Article

References (15)

1. Yin JJ, Pollock CB, Kelly K. Mechanisms of cancer metastasis to the bone. Cell Res 2005;/15:/57-62.
2. Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;/350:/1655-64.
3. Mundy GR. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002;/2:/584-93.
4. Lin A, Ray ME. Targeted and systemic radiotherapy in the treatment of bone metastasis. Cancer Metastasis Rev 2006;/ 25:/669-75.
5. Nielsen OS, Bentzen SM, Sandberg E, Gadeberg CC, Timothy AR. Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases. Radiother Oncol 1998;/47:/233-40.
6. Salazar OM, Scarantino CW. Theoretical and practical uses of elective systemic (half-body) irradiation after 20 years of experimental designs. Int J Radiat Oncol Biol Phys 1997;/39:/ 907-13.
7. Korb L. Radiotherapy for the palliation of prostate cancer. Semin Surg Oncol 2000;/18:/75-9.
8. Salazar OM, Scarantino CW, Rubin P, Feldstein ML, Keller BE. Total (half-body) systemic irradiation for occult metastases in non-small cell lung cancer: An Eastern Cooperative Oncology Group pilot report. Cancer 1980;/46:/1932-44.
9. Qasim MM. Half body irradiation (HBI) in metastatic carcinomas. Clin Radiol 1981;/32:/215-9.
10. Wilkins MF, Keen CW. Hemi-body radiotherapy in the management of metastatic carcinoma. Clin Radiol 1987;/38:/ 267-8.
11. Salazar OM, Rubin P, Hendrickson FR, Komaki R, Poulter C, Newall J, et al. Single-dose half-body irradiation for palliation of multiple bone metastases from solid tumors. Final Radiation Therapy Oncology Group report. Cancer 1986;/58:/29-36.
12. Gocheva L, Todorov J, Danon S. Tolerance of half-body irradiation as systemic therapy for patients with locally advanced breast cancer. Med Pediatr Oncol 1999;/33:/ 558-62.
13. Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 1998;/16:/139-44.
14. Tong D, Gillick L, Hendrickson FR. The palliation of symptomatic osseous metastases: Final results of the Study by the Radiation Therapy Oncology Group. Cancer 1982;/ 50:/893-9.
15. Salazar OM, Sandhu T, da Motta NW, Escutia MA, Lanzos- Gonzales E, Mouelle-Sone A, et al. Fractionated half-body irradiation (HBI) for the rapid palliation of widespread, symptomatic, metastatic bone disease: A randomized Phase III trial of the International Atomic Energy Agency (IAEA). Int J Radiat Oncol Biol Phys 2001;/50:/765-75.