Options for fertility preservation in pediatric populations undergoing cancer chemotherapy

Pediatric Endocrinology Reviews

Volumn 6, Issue SUPPL. 2, 2009, Pages 306-314

  Martin, Joseph Ryan ^a   Patrizio, Pasquale ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

Adolescents; Cancer; Chemotherapy; Children; Fertility; Infertility

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; BUSULFAN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; FOLLITROPIN; GONADORELIN AGONIST; PLATINUM DERIVATIVE;

ACUTE LYMPHOBLASTIC LEUKEMIA; AUTOTRANSPLANTATION; BIRTH DEFECT; CANCER SURVIVOR; CHILDHOOD CANCER; CONFERENCE PAPER; CONGENITAL DISORDER; CRYOPRESERVATION; DRUG MEGADOSE; EARLY MENOPAUSE; FEMALE FERTILITY; FERTILIZATION IN VITRO; GAMETE; GERM CELL TUMOR; GONAD DYSFUNCTION; HORMONAL REGULATION; HUMAN; INFERTILITY; INFERTILITY THERAPY; INFORMED CONSENT; MALE FERTILITY; NONHUMAN; OLIGOSPERMIA; OSTEOSARCOMA; OVARY DISEASE; OVARY INSUFFICIENCY; PATIENT MONITORING; POPULATION RESEARCH; QUALITY OF LIFE; SPERMATOGENESIS; SUBFERTILITY; TESTIS BIOPSY; TESTIS DISEASE;

ADOLESCENT; ANTINEOPLASTIC AGENTS; CHILD; FEMALE; FERTILITY; HUMANS; INFERTILITY; INFORMED CONSENT; MALE; NEOPLASMS; SURVIVORS;

EID: 65549097266     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (88)

1. Ries LAG, Melbert D, Krapcho M, Mariotto A, Miller BA, Feuer EJ, Clegg L, Horner MJ, Howlader N, Eisner MP, Reichman M, Edwards BK. SEER Cancer Statistics Review, 1975-2004, National Cancer Institute. Bethesda, MID
2. Hudson MM, Mertens AC, Yasui Y, Hobbie W, Chen H, Gurney JG, Yeazel M, Recklitis CJ, Marina N, Robison LR, Oeffinger KC. Health status of adult tong-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. JAMA 2003;290:1583-1592
3. Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: who is at risk and what can be offered? Lancet Oncol 2005;6:209-218
4. Greenberg ML, Urbach SL. Preserving the fertility of children with cancer. Med J Aust 2006;185:532-533
5. Sanders JE, Hawley J, Levy W, Gooley T, Buckner CD, Deeg HJ, Doney K, Storb R, Sullivan K, Witherspoon R, Appelbaum FR. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood 1996;87:3045-3052
6. Spunt SL, Sweeney TA, Hudson MM, Billups CA, Krasin MJ, Hester AL. Late effects of pelvic rhabdomyosarcoma and its treatment in female survivors. J Clin Oncol 2005;23:7143-7151
7. Wallace WH, Shalet SM, Tetlow LJ, Morris-Jones PH. Ovarian function following the treatment of childhood acute lymphoblastic leukaemia. Med Pediatr Oncol 1993;21:333-339
8. Kenney LB, Laufer MR, Grant FD, Grier H, Diller L. High risk of infertility and long term gonadal damage in males treated with high dose cyclophosphamide for sarcoma during childhood. Cancer 2001;91:613-621
9. Afify Z, Shaw PJ, Clavano-Harding A, Cowell CT. Growth and endocrine function in children with acute myeloid leukaemia after bone marrow transplantation using busulfan/cyclophosphamide. Bone Marrow Transplant 2000;25:1087-1092
10. Teinturier C, Hartmann O, Valteau-Couanet D, Benhamou E, Bougneres PF. Ovarian function after autologous bone marrow transplantation in childhood: high-dose busulfan is a major cause of ovarian failure. Bone Marrow Transplant 1998;22:989-994
11. Byrne J, Fears TR, Gail MH, Pee D, Connelly RR, Austin DF, Holmes GF, Holmes FF, Latourette HB, Meigs JW, Strong LC, Myers MH, Mulvihill JJ. Early menopause in long-term survivors of cancer during adolescence. Am J Obstet Gynecol 1992; 166:788-793
12. Gerl A, Muhlbayer D, Hansmann G, Mraz W, Hiddemann W. The impact of chemotherapy on Leydig cell function in long term survivors of germ cell tumors. Cancer 2001;91:1297-1303
13. Wallace WH, Shalet SM, Crowne EC, Morris-Jones PH, Gattamaneni HR, Price DA. Gonadal dysfunction due to cis-platinum. Med Pediatr Oncol 1989;17:409-413
14. Byrne J, Mulvihill JJ, Connelly RR, Austin DA, Holmes GE, Holmes FF, Latourette HB, Meigs JW, Strong LC, Myers MH. Reproductive problems and birth defects in survivors of Wilms' tumor and their relatives. Med Pediatr Oncol 1988;16:233-240
15. Green DM, Peabody EM, Nan B, Peterson S, Kalapurakal JA, Breslow NE. Pregnancy outcome after treatment for Wilms tumor: a report from the National Wilms Tumor Study Group. J Clin Oncol 2002;20:2506-2513
16. Stillman RJ, Schinfeld JS, Schiff I, Gelber RD, Greenberger J, Larson M, Jaffe N, Li FP. Ovarian failure in tong-term survivors of childhood malignancy. Am J Obstet Gynecol 1981;139:62-66
17. Hamre MR, Robison LL, Nesbit ME, Sather HN, Meadows AT, Ortega JA, D'Angio GJ, Hammond GD. Effects of radiation on ovarian function in long-term survivors of childhood acute lymphoblastic leukemia: a report from the Childrens Cancer Study Group. J Clin Oncol 1987;5:1759-1765
18. Livesey EA, Brook CG. Gonadal dysfunction after treatment of intracranial tumours. Arch Dis Child 1988;63:495-500
19. Wallace WH, Shalet SM, Crowne EC, Morris-Jones PH, Gattamaneni HR. Ovarian failure following abdominal irradiation in childhood: natural history and prognosis. Clin Oncol (R Coll Radiol) 1989;1:75-79
20. Kinsella TJ, Trivette G, Rowland J, Sorace R, Miller R, Fraass B, Steinberg SM, Glatstein E, Sherins RJ. Long-term follow-up of testicular function following radiation therapy for earty-stage Hodgkin's disease. J Clin Oncol 1989;7:718-724
21. Sklar CA, Robison LL, Nesbit ME, Sather HN, Meadows AT, Ortega JA, Kim TH, Hammond GD. Effects of radiation on testicular function in long-term survivors of childhood acute lymphoblastic leukemia: a report from the Children Cancer Study Group. J Clin Oncol 1990;8:1981-1987
22. Leiper AD, Grant DB, Chessells JM. Gonadal function after testicular radiation for acute lymphoblastic leukaemia. Arch Dis Child 1986;61:53-56
23. Rappaport R, Brauner R, Czernichow P, Thibaud E, Renier D, Zucker JM, Lemerle J. Effect of hypothalamic and pituitary irradiation on pubertal development in children with cranial tumors. J Clin Endocrinol Metab 1982;54:1164-1168
24. Constine LS, Woolf PD, Cann D, Mick G, McCormick K, Raubertas RF, Rubin P. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med 1993;328:87-94
25. Schmiegelow M, Lassen S, Poulsen HS, Schmiegelow K, Hertz H, Andersson AM, Skakkebaek NE, Muller J. Gonadal status in male survivors following childhood brain tumors. J Clin Endocrinol Metab 2001;86:2446-2452
26. Goodwin PJ, Ennis M, Pritchard KI, Trudeau M, Hood N. Risk of menopause during the first year after breast cancer diagnosis. J Clin Oncol 1999;17:2365-2370
27. Wallace WH, Shalet SM, Lendon M, Morris-Jones PH. Male fertility in long-term survivors of childhood acute lymphoblastic leukaemia. Int J Androl 1991;14:312-319
28. Thomson AB, Campbell AJ, Irvine DC, Anderson RA, Ketrar CJ, Wallace WH. Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case-control study. Lancet 2002;360:361-367
29. Lass A. The fertility potential of women with a single ovary. Hum Reprod Update 1999;5:546-550
30. Bath LE, Critchley HO, Chambers SE, Anderson RA, Kelnar CJ, Wallace WH. Ovarian and uterine characteristics after total body irradiation in childhood and adolescence: response to sex steroid replacement. Br J Obstet Gynaecol 1999;106:1265-1272
31. Speiser B, Rubin P, Casarett G. Aspermia following tower truncal irradiation in Hodgkin's disease. Cancer 1973;32:692-698
32. Recchia F, Sica G, De Filippis S, Saggio G, Rosselli M, Rea S. Goserelin as ovarian protection in the adjuvant treatment of premenopausal breast cancer: a phase II pilot study. Anticancer Drugs 2002;13:417-424
33. Franke HR, Smit WM, Vermes I. Gonadal protection by a gonadotropin-releasing hormone agonist depot in young women with Hodgkin's disease undergoing chemotherapy. Gynecol Endocrinol 2005;20:274-278
34. Waxman JH, Ahmed R, Smith D, Wrigley PF, Gregory W, Shalet S, Crowther D, Rees LH, Besser GM, Malpas JS, Lister TA. Failure to preserve fertility in patients with Hodgkin's disease. Cancer Chemother Pharmacol 1987;19:159-162
35. Blumenfeld Z, Avivi I, Ritter M, Rowe JM. Preservation of fertility and ovarian function and minimizing chemotherapy-induced gonadotoxicity in young women. J Soc Gynecol Investig 1999;6:229-239
36. Blumenfeld Z, Avivi I, Linn S, Epelbaum R, Ben-Shahar M, Haim N. Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy. Hum Reprod 1996;11:1620-1626
37. Meistrich M, Shetty G. Hormonal Suppression for Fertility Preservation in Males and Females. Reproduction 2008;136:691-701
38. Danforth DR, Arbogast LK, Friedman CI. Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists. Fertil Steril 2005;83:1333-1338
39. Clough KB, Goffinet F, Labib A, Renolleau C, Campana F, de la Rochefordiere A, Durand JC. Laparoscopic unilateral ovarian transposition prior to irradiation: prospective study of 20 cases. Cancer 1996;77:2638-2645
40. Visvanathan DK, Cutner AS, Cassoni AM, Gaze M, Davies MC. A new technique of laparoscopic ovariopexy before irradiation. Fertil Steril 2003;79:1204-1206
41. Williams RS, Littell RD, Mendenhall NP. Laparoscopic oophoropexy and ovarian function in the treatment of Hodgkin disease. Cancer 1999;86:2138-2142
42. Martin JR, Kodaman P, Oktay K, Taylor HS. Ovarian cryopreservation with transposition of a contralateral ovary: a combined approach for fertility preservation in women receiving pelvic radiation. Fertil Steril 2007;87:189:e5-e7
43. Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, Beck LN, Brennan W, Oktay K. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006;24:2917-2931
44. Oktay K, Cil AP, Bang H. Efficiency of oocyte cryopreservation: a meta-analysis. Fertil Steril 2006;86:70-80
45. Kuwayama M, Vajta G, Kato O, Leibo SP. Highly efficient vitrification method for cryopreservation of human oocytes. Reprod Biomed Online 2005;11:300-308
46. Katayama KP, Stehlik J, Kuwayama M, Kato O, Stehlik E. High survival rate of vitrified human oocytes results in clinical pregnancy. Fertil Steril 2003;80:223-224
47. Manipalviratn S, Decherney A. Clinical application of human oocyte cryopreservation. Rev Recent Clin Trials 2008;3:104-110
48. Huang JY, Tulandi T, Holzer H, Tan SL, Chian RC. Combining ovarian tissue cryobanking with retrieval of immature oocytes followed by in vitro maturation and vitrification: an additional strategy of fertility preservation. Fertil Steril 2008;89:567-572
49. Donnez J, Dolmans MM, Demylle D, Jadoul P, Pirard C, Squifflet J, Martinez-Madrid B, van Langendonckt A. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet 2004;364:1405-1410
50. Meirow D, Levron J, Eldar-Geva T, Hardan I, Fridman E, Zatel Y, Schiff E, Dor J. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. N Engl J Med 2005;353:318-321
51. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease. Oncologist 2007;12:1437-1442
52. Andersen CY, Rosendahl M, Byskov AG, Loft A, Ottosen C, Dueholm M, Schmidt KLT, Nyboe Andersen A, Ernst E. Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Hum Reprod 2008:den244
53. Silber SJ, Gosden RG. Ovarian transplantation in a series of monozygotic twins discordant for ovarian failure. N Engl J Med 2007;356:1382-1384
54. Silber SJ, Lenahan KM, Levine DJ, Pineda JA, Gorman KS, Friez MJ, Crawford EC, Gosden RG. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med 2005;353:58-63
55. Royal College of Obstetricians and Gynaecologists. Storage of ovarian and prepubertal testicular tissue: report of a working party. London, Royal College of Obstetricians and Gynaecologists 2000
56. Newton H, Aubard Y, Rutherford A, Sharma V, Gosden R. Low temperature storage and grafting of human ovarian tissue. Hum Reprod 1996;11:1487-1491
57. Patrizio P, Gavish Z, Martel M, Azodi M, Silber S, Arav A. Whole Human Ovaries Cryopreservation using a Novel Multigradient Freezing Device. Fertil Steril 2007;88:S355
58. Wang X, Chen H, Yin H, Kim SS, Lin Tan S, Gosden RG. Fertility after intact ovary transplantation. Nature 2002;415:385
59. Chen C, Chen S, Chang F, Wu G, Liu J, Yu C. Autologous heterotopic transplantation of intact rabbit ovary after cryopreservation. Hum Reprod 2005;20:(Suppl 1):i149
60. Arav A, Revel A, Nathan Y, Bor A, Gacitua H, Yavin S, Gavish Z, Uri M, Elami A. Oocyte recovery, embryo development and ovarian function after cryopreservation and transplantation of whole sheep ovary. Hum Reprod 2005;20:3554-3559
61. Bedaiwy MA, Jeremias E, Gurunluoglu R, Hussein MR, Siemianow M, Biscotti C, Falcone T. Restoration of ovarian function after autotransplantation of intact frozen-thawed sheep ovaries with microvascular anastomosis. Fertil Steril 2003;79:594-602
62. Imhof M, Bergmeister H, Lipovac M, Rudas M, Hofstetter G, Huber J. Orthotopic microvascular reanastomosis of whole cryopreserved ovine ovaries resulting in pregnancy and live birth. Fertil Steril 2006;85(Suppl 1):1208-1215
63. Chian RC, Gilbert L, Huang JY, Demirtas E, Holzer H, Benjamin A, Buckett WM, Tulandi T, Tan SL. Live birth after vitrification of in vitro matured human oocytes. Fertil Steril 2008
64. Hubner K, Fuhrmann G, Christenson LK, Kehler J, Reinbold R, De La Fuente R, Wood J, Strauss JF, 3rd, Boiani M, Scholer HR. Derivation of oocytes from mouse embryonic stem cells. Science 2003;300:1251-1256
65. Tilly JL, Niikura Y, Rueda BR. The Current Status of Evidence for and Against Postnatal Oogenesis in Mammals: A Case of Ovarian Optimism Versus Pessimism? Biol Reprod 2008
66. Tilly JL, Rueda BR. Stem cell contribution to ovarian development, function, and disease. Endocrinology 2008;149:4307-4311
67. Muller J, Sonksen J, Sommer P, Schmiegelow M, Petersen PM, Heilman C, Schmiegelow K. Cryopreservation of semen from pubertal boys with cancer. Med Pediatr Oncol 2000;34:191-194
68. Chung K, Irani J, Knee G, Efymow B, Blasco L, Patrizio P. Sperm cryopreservation for male patients with cancer: an epidemiological analysis at the University of Pennsylvania. Eur J Obstet Gynecol Reprod Biol 2004;113(Suppl 1):S7-S11
69. Lass A, Akagbosu F, Abusheikha N, Hassouneh M, Blayney M, Avery S, Brinsden P. A programme of semen cryopreservation for patients with malignant disease in a tertiary infertility centre: lessons from 8 years' experience. Hum Reprod 1998;13:3256-3261
70. Schover LR, Brey K, Lichtin A, Lipshultz LI, Jeha S. Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors. J Clin Oncol 2002;20:1880-1889
71. Honaramooz A, Snedaker A, Boiani M, Scholer H, Dobrinski I, Schlatt S. Sperm from neonatal mammalian testes grafted in mice. Nature 2002;418:778-781
72. Frederickx V, Michiels, A, Goossens E, De Block G, Van Steirteghem AC, Tournaye H. Recovery, survival and functional evaluation by transplantation of frozen-thawed mouse germ cells. Hum Reprod 2004;19:948-953
73. Schlatt S, Honaramooz A, Ehmcke J, Goebell. PJ, Rubben H, Dhir R, Dobrinski I, Patrizio P. Limited survival of adult human testicular tissue as ectopic xenograft. Hum Reprod 2006;21:384-389
74. Wallace WH, Walker DA. Conference consensus statement: ethical and research dilemmas for fertility preservation in children treated for cancer. Hum Fertil (Camb) 2001;4:69-76
75. Grundy R, Larcher V, Gosden RG, Hewitt M, Leiper A, Spoudeas HA, Walker D, Wallace WH. Fertility preservation for children treated for cancer (2): ethics of consent for gamete storage and experimentation. Arch Dis Child 2001;84:360-362
76. Human Fertilisation and Embryology Act. Human Fertitisation and Embryology Act 1990; chapter 37 (London: HMSO) 1990
77. Patrizio P, Butts S, Caplan A. Ovarian tissue preservation and future fertility: emerging technologies and ethical considerations. J Natl Cancer Inst Monogr 2005:107-110
78. Shaw JM, Bowles J, Koopman P, Wood EC, Trounson AO. Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. Hum Reprod 1996;11:1668-1673
79. Jahnukainen K, Hou M, Petersen C, Setchell B, Soder O. Intratesticular transplantation of testicular cells from leukemic rats causes transmission of leukemia. Cancer Res 2001;61:706-710
80. Oktay K. Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patients. Hum Reprod Update 2001;7:526-534
81. Gook DA, McCully BA, Edgar DH, McBain JC. Development of antral follicles in human cryopreserved ovarian tissue following xenografting. Hum Reprod 2001;16:417-422
82. Oktay K, Newton H, Gosden RG. Transplantation of cryopreserved human ovarian tissue results in follicle growth initiation in SCID mice. Fertil Steril 2000;73:599-603
83. Tesarik J, Bahceci M, Ozcan C, Greco E, Mendoza C. Restoration of fertility by in-vitro spermatogenesis. Lancet 1999;353:555-556
84. Eppig JJ, O'Brien MJ. Development in vitro of mouse oocytes from primordial follicles. Biol Reprod 1996;54:197-207
85. Schroder CP, Timmer-Bosscha H, Wijchman JG, de Leij LF, Hottema H, Heineman MJ, de Vries EG. An in vitro model for purging of tumour cells from ovarian tissue. Hum Reprod 2004; 19:1069-1075
86. Fossa SD, Magelssen H, Melve K, Jacobsen AB, Langmark F, Skjaerven R. Parenthood in survivors after adulthood cancer and perinatal health in their offspring: a preliminary report. J Natl Cancer Inst Monogr 2005:77-82
87. Hawkins MM, Draper GJ, Smith RA. Cancer among 1,348 offspring of survivors of childhood cancer. Int J Cancer 1989;43:975-978
88. Byrne J, Rasmussen SA, Steinhorn SC, Connelly RR, Myers MH, Lynch CF, Flannery J, Austin DF, Holmes FF, Holmes GE, Strong LC, Mulvihill JJ. Genetic disease in offspring of long-term survivors of childhood and adolescent cancer. Am J Hum Genet 1998;62:45-52