Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells

Journal of Neuroscience Research

Volumn 87, Issue 6, 2009, Pages 1412-1423

  Nakazawa, Toru ^a   Shimura, Masahiko ^b   Mourin, Ryu ^a   Kondo, Mineo ^c   Yokokura, Shunji ^a   Saido, Takaomi C ^d   Nishida, Kohji ^a   Endo, Shogo ^e  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NTT East Tohoku Hospital   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^e OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

Author keywords

Calpain; Excitatory amino acids; G substrate; Neuroprotection; Signal transduction

Indexed keywords

CALPAIN; CALPAIN 3; CYCLIC GMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; G SUBSTRATE; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN; UNCLASSIFIED DRUG; ACETYLLEUCYL LEUCYL NORLEUCINAL; ACETYLLEUCYL-LEUCYL-NORLEUCINAL; CALPAIN INHIBITOR III; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; G-SUBSTRATE; LEUPEPTIN; N METHYLASPARTIC ACID; NERVE PROTEIN; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITOR INTERACTION; ENZYME SUBSTRATE; EXCITOTOXICITY; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RETINA AMACRINE CELL; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; CELL DEATH; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; NICK END LABELING; PATHOLOGY; PHYSIOLOGY; RETINA; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

AMACRINE CELLS; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CALPAIN; CELL DEATH; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LEUPEPTINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RETINA;

EID: 65549090557     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21953     Document Type: Article

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