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Volumn 4, Issue 4, 2009, Pages 670-679

Structure-activity relationships and binding mode in the human acetylcholinesterase active site of Pseudo-irreversible inhibitors related to xanthostigmine

(9) Rizzo, Stefano a Cavalli, Andrea a,b Ceccarini, Luisa a Bartolini, Manuela a Belluti, Federica a Bisi, Alessandra a Andrisano, Vincenza a Recanatini, Maurizio a Rampa, Angela a

a UNIVERSITY OF BOLOGNA (Italy)

b ISTITUTO ITALIANO DI TECNOLOGIA (Italy)

Author keywords

Alzheimer's disease; Coumarins; Drug design; Flavones; Neurological agents

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN; BENZOPYRAN DERIVATIVE; CHOLINESTERASE INHIBITOR; NITROGEN; XANTHONE DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN AGGREGATION; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; COMPUTER SIMULATION; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

EID: 65549084980 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200800396 Document Type: Article

Times cited : (28)

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