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Volumn 20, Issue 12, 2009, Pages
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A novel method for the separation and determination of non-encapsulated pyrene in plasma and its application in pharmacokinetic studies of pyrene-loaded MPEG-PLA based nanoparticles
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Author keywords
[No Author keywords available]
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Indexed keywords
COEFFICIENTS OF VARIATIONS;
DRUG CONCENTRATIONS;
ENCAPSULATED DRUGS;
EVALUATION RESULTS;
EXTRACTABILITY;
EXTRACTANT;
EXTRACTION RECOVERIES;
FEMALE WISTAR RATS;
HIGH SPECIFICITIES;
LINEAR RELATIONSHIPS;
LIQUID-LIQUID EXTRACTIONS;
N HEPTANES;
NOVEL METHODS;
PHARMACOKINETIC STUDIES;
REPRODUCIBILITY;
LIQUIDS;
MOTION PICTURE EXPERTS GROUP STANDARDS;
NANOPARTICLES;
PLASMAS;
SOLVENT EXTRACTION;
PHARMACOKINETICS;
HEPTANE;
MACROGOL;
MACROGOL DERIVATIVE;
METHOXY POLYETHYLENE GLYCOL POLYLACTIDE;
NANOPARTICLE;
POLYLACTIDE;
PYRENE;
UNCLASSIFIED DRUG;
METHOXY POLY(ETHYLENE GLYCOL) POLY(LACTIDE);
METHOXY POLY(ETHYLENE GLYCOL)-POLY(LACTIDE);
POLYESTER;
PYRENE DERIVATIVE;
SOLVENT;
ACCURACY;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DIAGNOSTIC ACCURACY;
DRUG BLOOD LEVEL;
DRUG CAPSULE;
DRUG DETERMINATION;
DRUG FORMULATION;
DRUG HALF LIFE;
DRUG ISOLATION;
DRUG STABILITY;
ENCAPSULATION;
FEMALE;
LIQUID LIQUID EXTRACTION;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
REPRODUCIBILITY;
WISTAR RAT;
ANIMAL;
CHEMISTRY;
PHARMACOKINETICS;
PLASMA;
REGRESSION ANALYSIS;
STATISTICAL MODEL;
ANIMALS;
DRUG STABILITY;
FEMALE;
LEAST-SQUARES ANALYSIS;
LINEAR MODELS;
NANOPARTICLES;
PHARMACOKINETICS;
PLASMA;
POLYESTERS;
POLYETHYLENE GLYCOLS;
PYRENES;
RATS;
RATS, WISTAR;
REPRODUCIBILITY OF RESULTS;
SOLVENTS;
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EID: 65549083405
PISSN: 09574484
EISSN: 13616528
Source Type: Journal
DOI: 10.1088/0957-4484/20/12/125701 Document Type: Article |
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Times cited : (3)
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References (20)
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