Quinine levels in patients with uncomplicated falciparum malaria in the Amazon region of Brazil

Brazilian Journal of Infectious Diseases

Volumn 12, Issue 5, 2008, Pages 353-354

  Viera, José Luiz Fernandes ^a   Borges, Larissa Maria Guimarães ^a   Nascimento, Margareth Tavares Silva ^a   Gomes, Andreza de L S ^a  

^a FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Falciparum malaria; Quinine; Treatment

Indexed keywords

DOXYCYCLINE; PRIMAQUINE; QUININE; ANTIMALARIAL AGENT;

ADULT; ARTICLE; BLOOD SAMPLING; BRAZIL; CLINICAL ARTICLE; CLINICAL TRIAL; CONVALESCENCE; DRUG BLOOD LEVEL; ENDEMIC DISEASE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALARIA; MALARIA FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; SEX DIFFERENCE; TREATMENT DURATION; TREATMENT OUTCOME; ANIMAL; BLOOD; DRUG COMBINATION; DRUG MONITORING; PROSPECTIVE STUDY;

ADULT; ANIMALS; ANTIMALARIALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOXYCYCLINE; DRUG MONITORING; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; PROSPECTIVE STUDIES; QUININE;

EID: 65449185905     PISSN: 14138670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. WHO. World Health Organization- Guidelines for the treatment of malaria. Switzerland. 2006.
2. Pukrittayakamee S., Wanwimolruk S., Stepniewska K., et al. Quinine Pharmacokinetic- Pharmacodynamic Relationships in uncomplicated falciparum malaria. Antimicrob Agents Chemother 2003;47:3458-63.
3. Pukrittayakamee S., Looareesuwan S., Keeratithakul D., et al. A study of the factors affecting the metabolic clearance of quinine in malaria. Eur J Clin Pharmacol 1997;52:487-93.
4. Supanaranond W., Davis T.M., Pukritayakamee S., et al. Disposition of oral quinine in acute falciparum malaria. Eur J Clin Pharmacol 1991;40:49-52.
5. White N.J. Assessment of the pharmacodynamic properties of antimalarial drugs in vivo. Antimicrob Agents Chemother 1997;41:1413-22.
6. Brasil. Fundação Nacional de Saúde. Manual de Terapêutica da Malária. 2nd. Brasilia, 2001.
7. Dua K.V., Sarin R., Prakash A. Determination of quinine in serum, plasma, red blood cells and whole blood in healthy and Plasmodium falciparum malaria cases by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 1993;614:87-93.
8. Flanag K.L., Sharp M.B., Doherty T., Whitty C.J.M. Quinine levels revisited: the value of routine drug level monitoring for those on parenteral therapy. Acta Trop 2006;97:233-7.