Pathology of the spinal cord of C57BL/6J mice infected with rabies Virus (CVS-11 Strain)

Journal of Veterinary Medical Science

Volumn 71, Issue 3, 2009, Pages 319-324

  Kojima, Daisuke ^a   Park, Chun Ho ^a   Satoh, Yusuke ^a   Inoue, Satoshi ^b   Noguchi, Akira ^b   Oyamada, Toshifumi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Experimental study; Mouse spinal cord; Pathogenesis; Rabies (CVS 11)

Indexed keywords

ANTIBODY; CASPASE 3;

ANIMAL; APOPTOSIS; ARTICLE; C57BL MOUSE; CLASSIFICATION; CYTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; MOUSE; NICK END LABELING; PATHOLOGY; RABIES; RABIES VIRUS; SPINAL CORD; VIROLOGY;

ANIMALS; ANTIBODIES; APOPTOSIS; CASPASE 3; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; RABIES; RABIES VIRUS; SPINAL CORD;

MUS; RABIES VIRUS;

EID: 65449161836     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.71.319     Document Type: Article

References (31)

1. Baloul, L., Camelo, S. and Lafon, M. 2004. Up-regulation of Fas ligand (FasL) in the central nervous system: A mechanism of immune evasion by rabies virus. J. Neurovirol. 10: 372-382.
2. Baloul, L. and Lafon, M. 2003. Apoptosis and rabies virus neuroinvasion. Biochimie 85: 777-788.
3. Carson, M. J. 2002. Microglia as liaisons between the immune and central nervous systems: Functional implications for multiple sclerosis. Glia 40: 218-231.
4. Coulon, P., Derbin, C., Kucera, P., Lafay, F., Prehaud, C. and Flamand A. 1989. Invasion of the peripheral nervous systems of adult mice by the CVS strain of rabies virus and its avirulent derivative AvO1. J. Virol. 63: 3550-3554.
5. Dietzschold, B., Schnell, M. and Koprowski H. 2005. Pathogenesis of rabies. Curr. Top. Microbiol. Immunol. 292: 45-56.
6. Farina, C., Aloisi, F. and Meinl, E. 2007. Astrocytes are active players in cerebral innate immunity. Trends Immunol. 28: 138-145.
7. Faulkner, J. R., Herrmann, J. E., Woo M. J., Tansey K. E., Doan N. B. and Sofroniew M. V. 2004. Reactive astrocytes protect tissue and preserve function after spinal cord injury. J. Neurosci. 24: 2143-2155.
8. Guigoni, C. and Coulon, P. 2002. Rabies virus is not cytolytic for rat spinal motoneurons in vitro. J. Neurovirol. 8: 306-317.
9. Inoue, K. 2002. Microglial activation by purines and pyrimidines. Glia 40: 156-163.
10. Inoue, S., Sato, Y., Hasegawa, H., Noguchi, A., Yamada, A., Kurata, T. and Iwasaki, T. 2003. 2003. Cross-reactive antigenicity of nucleoproteins of lyssaviruses recognized by a monospecific antirabies virus nucleoprotein antiserum on paraffin sections of formalin-fixed tissues. Pathol. Int. 53: 525-533.
11. Iwasaki, Y., Gerhard, W. and Clark, H. F. 1977. Role of host immune response in the development of either encephalitic or paralytic disease after experimental rabies infection in mice. Infect. Immunol. 18: 220-225.
12. Jackson, A. C. 2002. Update on rabies. Curr. Opin. Neurol. 15: 327-331.
13. Jackson, A. C. and Park, H. 1998. Apoptotic cell death in experimental rabies in suckling mice. Acta Neuropathol. 95: 159-164.
14. Jackson, A. C. and Reimer, D. L. 1989. Pathogenesis of experimental rabies in mice: an immunohistochemical study. Acta Neuropathol. 78: 159-165.
15. Jackson, A. C. and Rossiter, J. P. 1997. Apoptosis plays an important role in experimental rabies virus infection. J. Virol. 71: 5603-5607.
16. Lafon, M. 2004. Subversive neuroinvasive strategy of rabies virus. Arch. Virol. 18: 149-159.
17. Meda, L., Cassatella, M. A., Szendrei G. I., Otvos Jr. L., Baron P., Villalba. M., Ferrari, D. and Rossi, F. 1995. Activation of microglia cells by beta-amyloid protein and interferon-gamma. Nature 374: 647-650.
18. Miyamoto, K. and Matsumoto, S. 1967. Comparative studies between pathogenesis of street and fixed rabies infection. J. Exp. Med. 125: 447-456.
19. Mizuno, T., Kuno, R., Nitta, A., Nabeshima, T., Zhang, G., Kawanokuchi, J., Wang, J., Ji, n S., Takeuchi, H. and Suzumura, A. 2005. Protective effects of nicergoline against neuronal cell death induced by activated microglia and astrocytes. Brain Res. 1066: 78-85.
20. Murphy, F. A. 1977. Rabies pathogenesis. Arch. Virol. 54: 279-297.
21. Murphy, F. A., Bauer, S. P., Harrison, A. K. and Winn, W. C. 1973. Comparative pathogenesis of rabies and rabies-like viruses: Infection of the central nervous system and centrifugal spread of virus to peripheral tissues. Lab. Invest. 28: 361-376.
22. Myer, D. J., Gurkoff, G. G., Lee, S. M., Hovda, D. A. and Sofroniew, M. V. 2006. Essential protective roles of reactive astrocytes in traumatic brain injury. Brain 129: 2761-2772.
23. Niquet, J., Auvin, S., Archie, M., Seo, D. W., Allen, S., Sankar, R. and Wasterlain C. G. 2007. Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain. Epilepsia 48: 1203-1206.
24. Park, C. H., Kondo, M., Inoue, S., Noguchi, A., Oyamada, T., Yoshikawa, H. and Yamada, A. 2006. The histopathogenesis of paralytic rabies in six-week-old C57BL/6J mice following inoculation of the CVS-11 strain into the right triceps surae muscle. J. Vet. Med. Sci. 68: 589-595.
25. Rasalingam, P., Rossiter, J. P. and Jackson, A. C. 2005. Recombinant rabies virus vaccine strain SAD-l16 inoculated intracerebrally in young mice produces a severe encephalitis with extensive neuronal apoptosis. Can. J. Vet. Res. 69: 100-105.
26. Rutherford, M. and Jackson, A. C. 2004. Neuronal apoptosis in immunodeficient mice infected with the challenge virus standard strain of rabies virus by intracerebral inoculation. J. Neurovirol. 10: 409-413.
27. Sawada, M., Kondo, N., Suzumura, A. and Marunouchi, T. 1989. Production of tumor necrosis factor-alpha by microglia and astrocyte in culture. Brain Res. 491: 394-397.
28. Shoji, Y., Inoue, S., Nakamichi, K., Kurane, I., Sakai, T. and Morimoto, K. 2004. Generation and characterization of P genedeficient rabies virus. Virology 318: 295-305.
29. Streit, W. J. 2002. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40: 133-139.
30. Suzumura, A. 2002. Microglia: immunoregulatory cells in the central nervous system. Nagoya J. Med. Sci. 65: 9-20.
31. Weiland, F., Cox, J. H., Meyer, S., Dahme, E. and Reddehase, M. J. 1992. Rabies virus neuritic paralysis: immunopathogenesis of nonfatal paralytic rabies. J. Virol. 66: 5096-5099.