Simultaneous determination of seven active flavonols in the flowers of Abelmoschus manihot by HPLC

Journal of Chromatographic Science

Volumn 47, Issue 3, 2009, Pages 206-210

  Lai, Xianyin ^a,b   Liang, Hong ^a,b   Zhao, Yuying ^a,b   Wang, Bin ^a,b  

^a PEKING UNIVERSITY   (China)

^b Modern Research Center for Traditional Chinese Medicine   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ABELMOSCHUS; ABELMOSCHUS MANIHOT; MANIHOT ESCULENTA;

DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FLAVONOID; FLAVONOL DERIVATIVE; HIBIFOLIN; HYPERIN; MYRICETIN; QUERCETIN;

ARTICLE; CHEMISTRY; DRUG STABILITY; FLOWER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; OKRA; REPRODUCIBILITY;

ABELMOSCHUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FLAVONOIDS; FLAVONOLS; FLOWERS; INDICATORS AND REAGENTS; QUERCETIN; REPRODUCIBILITY OF RESULTS;

EID: 65449155104     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/47.3.206     Document Type: Article

References (35)

1. Delectis florae reipublicae popularis sinicae agendae academiae sinicae edita. Flora Republicae Popularis Sinicae. Science Press, Beijing, China, 1984; Vol. 49, No. 2, pp. 53.
2. Guojia Zhongyiyao Guanliju. ZhongHua Bencao. Shanghai Scientific & Techincal Publishers, Shanghai, Chian, 1999; No. 5, pp. 332.
3. N.N. Xiong, J.Y. Yu, and Y. Deng. 26 chyluria patients treated with the flower of Abelmoschus manihot and experiment, Iiaoning J. TCM 23: 232-33 (1996).
4. Y.M. Yao. Inhibition effect of the flower of Abelmoschus manihot extraction on diplococcus gonorrhoeae. Jiangsu J. TCM 15:43 (1994).
5. H.Z. Gu and J.B.Song. Progress of studies on Abelmoschus manihot (L.) Medic. J. Chin. Medic. Mater. 21:158-60 (1998).
6. D. Chen. Effect observation of Huangkuai Capsule on chronic nephritis. Chin. J. Integr. Tradit. Western Nephrol. 2:299-300 (2001).
7. X.L. Han and M.L. Situ. 82 cases of canker treated with cataplasm made from the flower of Abelmoschs manihot. Clin. J. Anhui TCM 9:308(1997).
8. S.H. Zhang. Outer treatment of small area burn applied with oil of Abelmoschs manihot. Lishizhen Medic. Mater. Medica Research 8: 96(1997).
9. X.Y. Lai, Y.Y. Zhao, and H. Liang. Studies on chemical constituents in flower of Abelmoschus manihot. China J. Chin. Mat. Med. 31: 1597-1600(2006).
10. X.R. Wang, Z.Q. Wang, and Y. Li. Studies on the chemical constituents of Abelmoschus manihot L. Medic. J. Integr. Plant Biol. 23: 222-27(1981).
11. X.R. Wang, Z.H. Zhou, A.Q. Du, and Z.M. Huang. Studies on the flavonol constituents of Abelmoschus manihot L. Medic. Chin. J. Natural Medic. 2: 91-92 (2004).
12. J.B. Lowey. Floral anthocyanins of some malesian Hibiscus species. Pytochemistry 15:1395-96 (1976).
13. X.Y. Lai, Y.Y. Zhao, H. Liang, Y.J. Bai, B. Wang, and D.A. Guo. SPE-HPLC method for the determination of four flavonols in rat plasma and urine after oral administration of Abelmoschus manihot extract. J. Chromatogr. B (2007).
14. S. Lee, S.H. Jung, Y.S. Lee, M. Yamada, B.K. Kim, K. Ohuchi, and K.H. Shin. Antiinflammatory activity of hyperin from Acanthopanax chiisanensis roots. Arch. Pharm. Res. 27: 628-32 (2004).
15. S.K. Waage and P.A. Hedin. Biologically-active flavonoids from Cossypiμm arboreμm. Phytochemistry 23: 2509-11 (1984).
16. P. Mahakunakorn, M. Tohda, Y. Murakami, K. Matsμmoto, and H. Watanabe. Antioxidant and free radical-scavenging activity of Choto-san and its related constituents. Biol. Pharm. Bull. 27: 38-46 (2004).
17. T. Yokozawa, E. Dong, Y. Kawai, M. Gemba, and M. Shimizu. Protective effects of some flavonoids on the renal cellular membrane. Experiment. Toxicol. Pathol. 51: 9-14 (1999).
18. Z.H. Zhou, A.Q. Du, X.R. Wang, and D.Q. Wang. Determination of total flavonoids in flower of Abelmoschus manihot L. Research Practice Chin. Medic. 19: 52-53 (2005).
19. B.Y. Xu. Content determination of quercetin with TLC scan in the flower of Abelmoschus manihot and its preparations, J. Nanjing Univ. TCM 12: 32 (1996).
20. Z.F. Yang, W.N. Wang, K. Yang, X.R. Wang, X.B. Yang, and Z.M. Hang. Determination of hyperoside, isoquerditrin and quercitrin-3'-glucoside in flos Abelmoschus manihot of different areas by HPLC. Pharmac. J. CPLA 21: 388-90 (2005).
21. X.Y. Lai, Y.Y. Zhao and H. Liang. A flavonoid glucuronide from Abelmoschus manihot(i.) Medik. Biochem. Syst. Ecol. 35: 891-93 (2007).
22. T. Barsseur and L. Angenot. Flavonol glycoside from leaves of Strychnos variabilis. Phytochemistry. 25: 563-64 (1986).
23. Z.D. Xia, A.Q. Du, H.P. Wang, Z.H. Zhou, and X.R. Wang. Chemical studies on the active constituents of Rhododendron micranthμm Turcz. J. China Pharm. Univ. 30: 314-15 (1999).
24. D.Q. Yu. Fenxi huaxue Shouce. Chemical Industry Press, Bejing, 1999: Vol. 7, pp. 818.
25. Z.Z. Zhang, D.A. Guo, C.L. Li, J.H. Zheng, Y.N. Xiaochi, Z.H. Jia, and T.B. Erjie, Studies on the chemical constituents of Caultheria yunnanensis (Franch) Rehd (III). Chin. Trad. Herbal Drμgs 30: 167-69(1999).
26. S.Z. Li. Bencao Gangmu. People's Medical Publishing House, Beijing, 1985; No. 1, pp. 1045.
27. Z.H. Liu, S.Q. Feng, and G.R. Li. Changes of total flavone in Abelmoschus Manihot Medic, affected by time difference in collection and different drying method, J. Nanjing Univ. TCM 15:157-59 (1999).
28. A.G.R. Nair, P. Ramesh, S.S. Subramanian, and B.S. Joshi. Melocorin - a new herbacetin glucuronide from Melochia cor-chorifolia. Indian J. Chem. Section B: Org. Including Medic. 15B: 1045 (1977).
29. A.J.A. Petrus. Polyphenolic components of Waltheria indica. Fitoterapia 61:371 (1990).
30. P. Ramesh and C.R. Yuvarajan. A new flavone methyl ether from Helicteres isora. J. Natural Products 58:1242-43 (1995).
31. A.G.R. Nair and S.S. Subramanian. Hibifolin, a new gossypetin glycoside from the flowers of Hibiscus vitifolius. Indian J. Chem. 12: 890-91 (1974).
32. M. Wolbis. Flavonol glycosides from Sedμm albμm. Phytochemistry 28: 2187-89 (1989).
33. R. Gunasegaran, A. Ubeda, M.J. Alcaraz, R. Jayaprakasam, and A.G.R. Nair. Acylated flavonol glucosides and other phenolics of Helichrysμm bracteatum. Pharmazie 48: 230-31 (1993).
34. M.L. Ferrandiz, A.G.R. Nair, and M.J. Alcaraz. Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs. Pharmazie 45: 206-208 (1990).
35. J.T.T. Zhu, R.C.Y. Choi, G.K.Y. Chu, A.W.H. Cheung, Q.T. Gao, J. Li, Z.Y. Jiang, T.T.X. Dong, and K.W.K. Tsim. Flavonoids possess neu-roprotective effects on cultured pheochromocytoma PC12 cells: a Comparison of different flavonoids in activating estrogenic effect and in preventing β-amyloid-induced cell death, J. Agric. Food Chem. 55(6):2438-45 (2007).