Antiinflammatory activity of hyperin from Acanthopanax chiisanensis roots

Archives of Pharmacal Research

Volumn 27, Issue 6, 2004, Pages 628-632

  Lee, Sanghyun ^a   Sang, Hoon Jung ^a,b   Yeon, Sil Lee ^a,c   Yamada, Masateru ^d   Kim, Bak Kwang ^a   Ohuchi, Kazuo ^d   Kuk, Hyun Shin ^a,c  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c World Sea Green Co Ltd   (South Korea)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Acanthopanax chiisanensis; Anti inflammatory activity; Araliaceae; Hyperin

Indexed keywords

DRUG DERIVATIVE; HYPERIN; NITRIC OXIDE SYNTHASE; NITRITE; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT; QUERCETIN;

ACANTHOPANAX; ANIMAL; ARTICLE; CAPILLARY PERMEABILITY; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOUSE; PERITONEUM MACROPHAGE; PLANT ROOT; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ACANTHOPANAX; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; INJECTIONS, INTRAPERITONEAL; MACROPHAGES, PERITONEAL; MALE; MICE; NITRIC OXIDE SYNTHASE; NITRITES; PLANT EXTRACTS; PLANT ROOTS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 21644443814     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02980162     Document Type: Article

References (9)

1. Bucar, F., Jachak, S. M., Noreen, Y., Nartnig, T., Perera, P., Bohlin, L., and Schubert-Zsilavecz, M., Amentoflavone from Biophytum sensitivum and its effect on COX-1/COX-2 catalysed prostaglandin biosynthesis. Planta Med., 64, 373-374 (1998).
2. 15N]nitrate in biological fluids. Anal. Biochem., 126, 131-138 (1982).
3. Kalkbrenner, F., Wurm, G., and Bruchhausen, F., In vitro inhibition and stimulation of purified prostaglandin endoperoxide synthase by flavonoids: structure-activity relationship. Pharmacol., 44, 1-12 (1992).
4. 2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. Biochim. Biophys. Acta, 1438, 399-407 (1999).
5. Lee, S., Jung, S. H., Lee, Y. S., and Shin, K. H., Hyperin, an aldose reductase inhibitor from Acanthopanax senticosus. Nat. Prod. Sci., 9, 4-6 (2003).
6. Nishizuka, Y., Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science, 258, 607-614 (1992).
7. 2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide. Biochim. Biophys. Acta, 834, 42-47 (1985).
8. Perry, L. M., "Medical Plants of East and Southeast Asia," MIT Press, Cambridge, Massachusetts and London, 1980, p. 41.
9. Wang, C. and Smith, R. L., Lowry determination of protein in the presence of Triton X-100. Anal. Biochem., 63, 414-417 (1975).