메뉴 건너뛰기




Volumn 214, Issue 5, 2009, Pages 744-751

An unbiased stereological study on subpopulations of rat liver macrophages and on their numerical relation with the hepatocytes and stellate cells

Author keywords

Disector; ED1; ED2; Kupffer cells; Liver; Optical fractionator

Indexed keywords

ACCURACY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELL STRUCTURE; CELL SUBPOPULATION; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; KUPFFER CELL; LIVER CELL; LIVER MACROPHAGE; MACROPHAGE; MACROPHAGE FUNCTION; MALE; MATHEMATICAL COMPUTING; NONHUMAN; PRIORITY JOURNAL; RAT; REFERENCE VALUE; STELLATE CELL; STEREOLOGY;

EID: 65449128453     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2009.01055.x     Document Type: Article
Times cited : (20)

References (54)
  • 1
    • 34249788177 scopus 로고    scopus 로고
    • Ischemic preconditioning in liver pathophysiology
    • Arai M, Tejima K, Ikeda H, et.al. (2007) Ischemic preconditioning in liver pathophysiology. J Gastroenterol Hepatol 22, S65-67.
    • (2007) J Gastroenterol Hepatol , vol.22
    • Arai, M.1    Tejima, K.2    Ikeda, H.3
  • 2
    • 0030273771 scopus 로고    scopus 로고
    • Functional characterization of two different Kupffer cell populations of normal rat liver
    • Armbrust T, Ramadori G (1996) Functional characterization of two different Kupffer cell populations of normal rat liver. J Hepatol 25, 518-528.
    • (1996) J Hepatol , vol.25 , pp. 518-528
    • Armbrust, T.1    Ramadori, G.2
  • 3
    • 0025690682 scopus 로고
    • Characterization and expression of the antigen present on resident rat macrophages recognized by monoclonal antibody ED2
    • BarbéE, Damoiseaux JGMC, Döpp EA, Dijkstra CD (1990) Characterization and expression of the antigen present on resident rat macrophages recognized by monoclonal antibody ED2. Immunobiology 182, 88-99.
    • (1990) Immunobiology , vol.182 , pp. 88-99
    • Barbé, E.1    Damoiseaux, J.G.M.C.2    Döpp, E.A.3    Dijkstra, C.D.4
  • 4
    • 0000294863 scopus 로고
    • The physiopathology of the reticuloendothelial cells of the liver and the spleen
    • Biozzi G, Stiffel C (1965) The physiopathology of the reticuloendothelial cells of the liver and the spleen. Prog Liver Dis 2, 166.
    • (1965) Prog Liver Dis , vol.2 , pp. 166
    • Biozzi, G.1    Stiffel, C.2
  • 5
    • 0017334065 scopus 로고
    • Distribution of organelles and membranes between hepatocytes and nonhepatocytes in rat liver parenchyma -A stereological study
    • Blouin A, Bolender RP, Weibel ER (1977) Distribution of organelles and membranes between hepatocytes and nonhepatocytes in rat liver parenchyma -A stereological study. J Cell Biol 72, 441-55.
    • (1977) J Cell Biol , vol.72 , pp. 441-455
    • Blouin, A.1    Bolender, R.P.2    Weibel, E.R.3
  • 6
    • 0018200301 scopus 로고
    • Integrated stereological and biochemical studies on hepatocytic membranes. I. Membrane recoveries in subcellular fractions
    • Bolender RP, Paumgartner D, Losa G, Muellener D, Weibel (1978) Integrated stereological and biochemical studies on hepatocytic membranes. I. Membrane recoveries in subcellular fractions. J Cell Biol 77, 565-83.
    • (1978) J Cell Biol , vol.77 , pp. 565-583
    • Bolender, R.P.1    Paumgartner, D.2    Losa, G.3    Muellener, D.4
  • 7
    • 0022552278 scopus 로고
    • Quantification, tissue distribution and proliferation kinetics of Kupffer cells in normal rat liver
    • Bouwens L, Baekeland M, De Zanger R, Wisse E (1986) Quantification, tissue distribution and proliferation kinetics of Kupffer cells in normal rat liver. Hepatology 6, 718-722.
    • (1986) Hepatology , vol.6 , pp. 718-722
    • Bouwens, L.1    Baekeland, M.2    De Zanger, R.3    Wisse, E.4
  • 9
    • 13444258359 scopus 로고    scopus 로고
    • Functional differences between periportal and perivenous Kupffer cells isolated by digitonin-collagenase perfusion
    • Bykov I, Ylipaasto P, Eerola L, Lindros KO (2004) Functional differences between periportal and perivenous Kupffer cells isolated by digitonin-collagenase perfusion. Comp Hepatol 3, S34.
    • (2004) Comp Hepatol , vol.3
    • Bykov, I.1    Ylipaasto, P.2    Eerola, L.3    Lindros, K.O.4
  • 10
    • 0025905107 scopus 로고
    • Maintenance of tumoricidal activity and susceptibility to reactivation of subpopulations of rat liver macrophages
    • Daemen T, Veninga A, Regts J, Scherphof GL (1991) Maintenance of tumoricidal activity and susceptibility to reactivation of subpopulations of rat liver macrophages. J Immunother 10, 200-206.
    • (1991) J Immunother , vol.10 , pp. 200-206
    • Daemen, T.1    Veninga, A.2    Regts, J.3    Scherphof, G.L.4
  • 12
    • 0021969667 scopus 로고
    • The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3
    • Dijkstra CD, Döpp EA, Joling P, Kraal G (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 54, 589-599.
    • (1985) Immunology , vol.54 , pp. 589-599
    • Dijkstra, C.D.1    Döpp, E.A.2    Joling, P.3    Kraal, G.4
  • 13
    • 13744255589 scopus 로고    scopus 로고
    • Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
    • Duffield JS, Forbes SJ, Constandinou CM, et al. (2005) Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 115, 56-65.
    • (2005) J Clin Invest , vol.115 , pp. 56-65
    • Duffield, J.S.1    Forbes, S.J.2    Constandinou, C.M.3
  • 14
    • 0017136296 scopus 로고
    • Heterogeneity of cells isolated from rat liver by pronase digestion: Ultrastructure, cytochemistry and cell culture
    • Emeis JJ, Planque B (1976) Heterogeneity of cells isolated from rat liver by pronase digestion: Ultrastructure, cytochemistry and cell culture. J Reticuloendothel Soc 20, 11-29.
    • (1976) J Reticuloendothel Soc , vol.20 , pp. 11-29
    • Emeis, J.J.1    Planque, B.2
  • 15
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis (from bench to bedside)
    • Friedman SL (2003) Liver fibrosis (from bench to bedside). J Hepatol 38, S38-S53.
    • (2003) J Hepatol , vol.38
    • Friedman, S.L.1
  • 17
    • 0036381089 scopus 로고    scopus 로고
    • The smooth fractionator
    • Gundersen HJ (2002) The smooth fractionator. J Microsc 207, 191-210.
    • (2002) J Microsc , vol.207 , pp. 191-210
    • Gundersen, H.J.1
  • 18
    • 84985187820 scopus 로고
    • Stereology of arbitrary particles: A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R Thompson
    • Gundersen HJG (1986) Stereology of arbitrary particles: A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R Thompson. J Microsc 143, 3-45.
    • (1986) J Microsc , vol.143 , pp. 3-45
    • Gundersen, H.J.G.1
  • 19
    • 0026728411 scopus 로고
    • Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation
    • Hardonk MJ, Dijkhuis FW, Hulstaert CE, Koudstaal J (1992) Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol 52, 296-302.
    • (1992) J Leukoc Biol , vol.52 , pp. 296-302
    • Hardonk, M.J.1    Dijkhuis, F.W.2    Hulstaert, C.E.3    Koudstaal, J.4
  • 20
    • 0027418782 scopus 로고
    • Isolation of cytotoxic Kupffer cells by a modified enzymatic assay: A methodological study
    • Heuff G, Steenbergen JJ, Van De Loosdrecht AA, et al. (1993) Isolation of cytotoxic Kupffer cells by a modified enzymatic assay: A methodological study. J Immunol Methods 159, 115-123.
    • (1993) J Immunol Methods , vol.159 , pp. 115-123
    • Heuff, G.1    Steenbergen, J.J.2    Van De Loosdrecht, A.A.3
  • 21
    • 0027404472 scopus 로고
    • In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury
    • Hines JE, Johnson SJ, Burt AD (1993) In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury. Am J Pathol 142, 511-518.
    • (1993) Am J Pathol , vol.142 , pp. 511-518
    • Hines, J.E.1    Johnson, S.J.2    Burt, A.D.3
  • 22
    • 0029061308 scopus 로고
    • Histochemical and electron microscopic characterization of hepatic macrophage subfractions isolated from normal and liposomal muramyl dipeptide treated rats
    • Hoedemakers RMJ, Atmosoerdjo-Briggs JA, Morselt HWM, Daemen T, Scherpof GL, Hardonk MJ (1995) Histochemical and electron microscopic characterization of hepatic macrophage subfractions isolated from normal and liposomal muramyl dipeptide treated rats. Liver 15, 113-120.
    • (1995) Liver , vol.15 , pp. 113-120
    • Hoedemakers, R.M.J.1    Atmosoerdjo-Briggs, J.A.2    Morselt, H.W.M.3    Daemen, T.4    Scherpof, G.L.5    Hardonk, M.J.6
  • 23
    • 0027266855 scopus 로고
    • Functional characteristics of the rat liver macrophage population after a single intravenous injection of liposome-encapsulated muramyl peptides
    • Hoedemakers RMJ, Vossebeld PJM, Daemen T, Scherphof GL (1993) Functional characteristics of the rat liver macrophage population after a single intravenous injection of liposome-encapsulated muramyl peptides. J Immunother 13, 252-60.
    • (1993) J Immunother , vol.13 , pp. 252-260
    • Hoedemakers, R.M.J.1    Vossebeld, P.J.M.2    Daemen, T.3    Scherphof, G.L.4
  • 25
    • 23044468372 scopus 로고    scopus 로고
    • Macrophage populations, myofibroblastic cells, and extracellular matrix accumulation in chronically-developing rat liver cirrhosis induced by repeated injection of thioacetamide
    • Ide M, Yamate J, Machida Y, et al. (2002) Macrophage populations, myofibroblastic cells, and extracellular matrix accumulation in chronically-developing rat liver cirrhosis induced by repeated injection of thioacetamide. J Toxicol Pathol 15, 19-29.
    • (2002) J Toxicol Pathol , vol.15 , pp. 19-29
    • Ide, M.1    Yamate, J.2    Machida, Y.3
  • 26
    • 24044546169 scopus 로고    scopus 로고
    • Minilaparotomy and full laparotomy, but not laparoscopy, alter the hepatic macrophage populations in a rat model
    • Jesch NK, Vieten G, Tschering T, Schroedel W, Ure BM (2005) Minilaparotomy and full laparotomy, but not laparoscopy, alter the hepatic macrophage populations in a rat model. Surg Endosc 19, 804-10.
    • (2005) Surg Endosc , vol.19 , pp. 804-810
    • Jesch, N.K.1    Vieten, G.2    Tschering, T.3    Schroedel, W.4    Ure, B.M.5
  • 27
    • 0026472556 scopus 로고
    • Phenotypic modulation of perisinusoidal cells following acute liver injury: A quantitative analysis
    • Johnson SJ, Hines JE, Burt AD (1992) Phenotypic modulation of perisinusoidal cells following acute liver injury: A quantitative analysis. Int J Exp Pathol 73, 765-772.
    • (1992) Int J Exp Pathol , vol.73 , pp. 765-772
    • Johnson, S.J.1    Hines, J.E.2    Burt, A.D.3
  • 29
    • 38449093343 scopus 로고    scopus 로고
    • Effect of high fat diet on the volume of liver and quantitative features of Kupffer cells in the female rat: A stereological and ultrastructural study
    • Kiki I, Altunkaynak BZ, Altunkaynak ME, Vuraler O, Unal D, Kaplan S (2007) Effect of high fat diet on the volume of liver and quantitative features of Kupffer cells in the female rat: A stereological and ultrastructural study. Obes Surg 17, 1381-1388.
    • (2007) Obes Surg , vol.17 , pp. 1381-1388
    • Kiki, I.1    Altunkaynak, B.Z.2    Altunkaynak, M.E.3    Vuraler, O.4    Unal, D.5    Kaplan, S.6
  • 30
    • 0036375875 scopus 로고    scopus 로고
    • Functional heterogeneity of the Kupffer cell population is involved in the mechanism of gadolinium chloride in rats administered endotoxin
    • Kono H, Fujii H, Asakawa M, et al. (2002) Functional heterogeneity of the Kupffer cell population is involved in the mechanism of gadolinium chloride in rats administered endotoxin. J Surg Res 106, 179-187.
    • (2002) J Surg Res , vol.106 , pp. 179-187
    • Kono, H.1    Fujii, H.2    Asakawa, M.3
  • 31
    • 0028266192 scopus 로고
    • Characterization of the interaction of galactose-exposing particles with rat Kupffer cells
    • Kuiper J, Bakeren HF, Biessen EA, Van Berkel TJC (1994a) Characterization of the interaction of galactose-exposing particles with rat Kupffer cells. Biochem J 299, 285-90.
    • (1994) Biochem J , vol.299 , pp. 285-290
    • Kuiper, J.1    Bakeren, H.F.2    Biessen, E.A.3    Van Berkel, T.J.C.4
  • 32
    • 0002982414 scopus 로고
    • Kupffer and sinusoidal endothelial cells
    • In (eds Arias IM, Boyer JL, Fausto N), New York: Raven Press, Ltd
    • Kuiper J, Brouwer A, Knook DL, Van Berkel TJC (1994b) Kupffer and sinusoidal endothelial cells. In The Liver: Biology and Pathobiology (eds Arias IM, Boyer JL, Fausto N), pp. 791-809. New York: Raven Press, Ltd.
    • (1994) The Liver: Biology and Pathobiology , pp. 791-809
    • Kuiper, J.1    Brouwer, A.2    Knook, D.L.3    Van Berkel, T.J.C.4
  • 33
    • 35348955787 scopus 로고    scopus 로고
    • Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury
    • Kumagai K, Kiyosawa N, Ito K, et al. (2007) Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury. Toxicology 241, 106-118.
    • (2007) Toxicology , vol.241 , pp. 106-118
    • Kumagai, K.1    Kiyosawa, N.2    Ito, K.3
  • 34
    • 0001860430 scopus 로고    scopus 로고
    • Developmental anatomy and normal structure
    • In (eds MacSween RNM, Burt AD, Portmann KG, Ishak KG, Scheuer PJ, Anthony PP) New York: Churchill Livingstone
    • MacSween RNM, Desmet VJ, Roskams T, Scothorne RJ (2002) Developmental anatomy and normal structure. In Pathology of the liver (eds MacSween RNM, Burt AD, Portmann KG, Ishak KG, Scheuer PJ, Anthony PP), pp. 1-66. New York: Churchill Livingstone.
    • (2002) Pathology of the Liver , pp. 1-66
    • MacSween, R.N.M.1    Desmet, V.J.2    Roskams, T.3    Scothorne, R.J.4
  • 35
    • 0042745504 scopus 로고    scopus 로고
    • A new approach to an unbiased estimate of the hepatic stellate cell index in the rat liver: An example in healthy conditions
    • Marcos R, Rocha E, Henrique RM, Monteiro RA (2003) A new approach to an unbiased estimate of the hepatic stellate cell index in the rat liver: an example in healthy conditions. J Histochem Cytochem 51, 1101-114.
    • (2003) J Histochem Cytochem , vol.51 , pp. 1101-1114
    • Marcos, R.1    Rocha, E.2    Henrique, R.M.3    Monteiro, R.A.4
  • 36
    • 4344695230 scopus 로고    scopus 로고
    • Estimation of the number of stellate cells in a liver with the smooth fractionator
    • Marcos R, Monteiro RAF, Rocha E (2004) Estimation of the number of stellate cells in a liver with the smooth fractionator. J Microsc 215, 174-182.
    • (2004) J Microsc , vol.215 , pp. 174-182
    • Marcos, R.1    Monteiro, R.A.F.2    Rocha, E.3
  • 37
    • 33645978405 scopus 로고    scopus 로고
    • Design-based stereological estimation of hepatocyte number, by combining the smooth optical fractionator and immunocytochemistry with anti-carcinoembryonic antigen polyclonal antibodies
    • Marcos R, Monteiro RAF, Rocha E (2006) Design-based stereological estimation of hepatocyte number, by combining the smooth optical fractionator and immunocytochemistry with anti-carcinoembryonic antigen polyclonal antibodies. Liver Int 26, 116-124.
    • (2006) Liver Int , vol.26 , pp. 116-124
    • Marcos, R.1    Monteiro, R.A.F.2    Rocha, E.3
  • 38
    • 36048940086 scopus 로고    scopus 로고
    • Determination of hepatocellularity number in the rat
    • Marcos R, Monteiro RA, Rocha E (2007) Determination of hepatocellularity number in the rat. Toxicol In Vitro 21, 1692-1693.
    • (2007) Toxicol In Vitro , vol.21 , pp. 1692-1693
    • Marcos, R.1    Monteiro, R.A.2    Rocha, E.3
  • 40
    • 0025823187 scopus 로고
    • The role of Kupffer cells in glucan-induced granuloma formation in the liver of mice depleted of blood monocytes by administration of strontium-89
    • Naito M, Takahashi K (1991) The role of Kupffer cells in glucan-induced granuloma formation in the liver of mice depleted of blood monocytes by administration of strontium-89. Lab Invest 64, 664-674.
    • (1991) Lab Invest , vol.64 , pp. 664-674
    • Naito, M.1    Takahashi, K.2
  • 41
    • 0031830884 scopus 로고    scopus 로고
    • Isolation and primary culture of rat Kupffer cells
    • Olynyk JK, Clarke SL (1998) Isolation and primary culture of rat Kupffer cells. J Gastroenterol Hepatol 13, 842-845.
    • (1998) J Gastroenterol Hepatol , vol.13 , pp. 842-845
    • Olynyk, J.K.1    Clarke, S.L.2
  • 42
    • 14944343292 scopus 로고    scopus 로고
    • Fibrosis in chronic liver diseases: Diagnosis and management
    • Pinzani M, Rombouts K, Colagrande S (2005) Fibrosis in chronic liver diseases: Diagnosis and management. J Hepatol 42, S22-S36.
    • (2005) J Hepatol , vol.42
    • Pinzani, M.1    Rombouts, K.2    Colagrande, S.3
  • 43
    • 33644544110 scopus 로고    scopus 로고
    • The liver as an immunological organ
    • Racanelli V, Rehermann B (2006) The liver as an immunological organ. Hepatology 43, S54-S62.
    • (2006) Hepatology , vol.43
    • Racanelli, V.1    Rehermann, B.2
  • 44
    • 0033789892 scopus 로고    scopus 로고
    • Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
    • Schmitz C, Hof PR (2000) Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J Chem Neuroanat 20, 93-114.
    • (2000) J Chem Neuroanat , vol.20 , pp. 93-114
    • Schmitz, C.1    Hof, P.R.2
  • 45
    • 0020379865 scopus 로고
    • Relation between localization and function of rat liver Kupffer cells
    • Sleyster EC, Knook DL (1982) Relation between localization and function of rat liver Kupffer cells. Lab Invest 47, 484-490.
    • (1982) Lab Invest , vol.47 , pp. 484-490
    • Sleyster, E.C.1    Knook, D.L.2
  • 46
    • 33749838238 scopus 로고    scopus 로고
    • Determination of the hepatocellularity number for human, dog, rabbit, rat and mouse livers from protein concentration measurements
    • Sohlenius-Sternbeck AK (2006) Determination of the hepatocellularity number for human, dog, rabbit, rat and mouse livers from protein concentration measurements. Toxicol in Vitro 20, 1582-86.
    • (2006) Toxicol in Vitro , vol.20 , pp. 1582-1586
    • Sohlenius-Sternbeck, A.K.1
  • 48
    • 0031769880 scopus 로고    scopus 로고
    • Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation in vitro
    • Thompson KC, Trowern A, Fowell A, et al. (1998) Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation in vitro. Hepatology 28, 1518-24.
    • (1998) Hepatology , vol.28 , pp. 1518-1524
    • Thompson, K.C.1    Trowern, A.2    Fowell, A.3
  • 49
    • 0000962547 scopus 로고    scopus 로고
    • The role of Kupffer cells in liver injury
    • In (eds Wisse E, Knook Dl, Balabaud C), Leiden: Kupffer Cell Foundation
    • Tsukamoto H, Lin M (1997) The role of Kupffer cells in liver injury. In Cells of the Hepatic Sinusoid, Vol. 6 (eds Wisse E, Knook Dl, Balabaud C), pp. 244-250. Leiden: Kupffer Cell Foundation.
    • (1997) Cells of the Hepatic Sinusoid , vol.6 , pp. 244-250
    • Tsukamoto, H.1    Lin, M.2
  • 50
    • 0037258442 scopus 로고    scopus 로고
    • Isolation of rat Kupffer cells: A combined methodology for highly purified primary cultures
    • Valatas V, Xidakis C, Roumpaki H, Kolios G, Kouroumalis EA (2003) Isolation of rat Kupffer cells: A combined methodology for highly purified primary cultures. Cell Biol Int 27, 67-73.
    • (2003) Cell Biol Int , vol.27 , pp. 67-73
    • Valatas, V.1    Xidakis, C.2    Roumpaki, H.3    Kolios, G.4    Kouroumalis, E.A.5
  • 51
    • 0009490209 scopus 로고
    • Ueber die sogennanten Sternzellen der Säugethierleber
    • Von Kupffer C (1899) Ueber die sogennanten Sternzellen der Säugethierleber. Arch Mikr Anat 54, 254-88.
    • (1899) Arch Mikr Anat , vol.54 , pp. 254-288
    • Von Kupffer, C.1
  • 52
    • 0016219689 scopus 로고
    • Observations on the fine structure and peroxidase cytochemistry of normal rat liver Kupffer cells
    • Wisse E (1974) Observations on the fine structure and peroxidase cytochemistry of normal rat liver Kupffer cells. J Ultrastruct Res 46, 393-426.
    • (1974) J Ultrastruct Res , vol.46 , pp. 393-426
    • Wisse, E.1
  • 53
    • 18844436013 scopus 로고    scopus 로고
    • Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide
    • Xidakis C, Ljumovic D, Manousou P, et al. (2005) Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide. Dig Dis Sci 50, 935-944.
    • (2005) Dig Dis Sci , vol.50 , pp. 935-944
    • Xidakis, C.1    Ljumovic, D.2    Manousou, P.3
  • 54
    • 0033198319 scopus 로고    scopus 로고
    • Participation of different cell types in the restituitive response of the rat liver to periportal injury induced by allyl alcohol
    • Yin L, Lynch D, Sell S (1999) Participation of different cell types in the restituitive response of the rat liver to periportal injury induced by allyl alcohol. J Hepatol 31: 497-507.
    • (1999) J Hepatol , vol.31 , pp. 497-507
    • Yin, L.1    Lynch, D.2    Sell, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.