Comparison of the phagocytosis of two types of cyclosporin (SDZ OXL 400 and SDZ IMM 125) by alveolar macrophages from hamsters

Cell Biology and Toxicology

Volumn 14, Issue 6, 1998, Pages 411-418

  Maye, I ^a   De Fraissinette, A ^b   Cruz Orive, L M ^c   Andersen, E ^b   Niederlander, C ^b   Bueb, W ^b   Froehlich, C ^b   Schreier, M ^b   Vonderscher, J ^b   Richter, F ^b   Cordier, A ^b   Gehr, P ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Cell activation; Cell viability; Cyclosporin; Phagocytosis; Stereology

Indexed keywords

CYCLOSPORIN A [8 DEXTRO O (2 HYDROXYETHYL)SERINE]; CYCLOSPORIN DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; DRUG UPTAKE; HAMSTER; HYDROPHILICITY; IMMUNOSUPPRESSIVE TREATMENT; LIVER TOXICITY; LUNG ALVEOLUS MACROPHAGE; NEPHROTOXICITY; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RESPIRATORY BURST;

ANIMALS; CELL SURVIVAL; CRICETINAE; CYCLOSPORINS; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-6; MACROPHAGES, ALVEOLAR; MESOCRICETUS; PHAGOCYTOSIS;

ANIMALIA; CRICETINAE;

EID: 6544244600     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007547612154     Document Type: Article

References (32)

1. Aarden LA, De Groot ER, Schaap OL, Lansdorp PM. Production of hybridoma growth factor by human monocytes. Eur J Immunol. 1987;17:1411-6.
2. Alexander AG, Barnes NC, Kay AB. Trial of cyclosporin in corticosteroid-dependent chronic severe asthma. Lancet. 1992;339:324-8.
3. Baddeley AJ, Gundersen HJG, Cruz-Orive LM. Estimation of surface area from vertical sections. J Microsc. 1986;142: 259-76.
4. Baumann G, Zenke G, Wenger R et al. Molecular mechanisms of immunosuppression. J Autoimmun. 1992;5:67-72.
5. Borel JF, Feurer C, Magnée C, Stähelin H. Effect of new anti-lymphotic peptide cyclosporine A in animals. Immunology. 1977;32:1017-25.
6. Borel JF, Di Padova F, Mason J, Quesniaux V, Ryffel B, Wenger R. Pharmacology of cyclosporine (Sandimmune). I. Introduction. Pharmacol Rev. 1989;41:239-42.
7. Conde M, Andrade J, Bedoya FJ, Santa Maria C, Sobrino F. Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity. Immunology. 1995;84:476-81.
8. Corrigan CJ, Hartnell A, Kay AB. T lymphocyte activation in acute severe asthma. Lancet. 1988;1129-32.
9. Corrigan CJ, Kay AB. CD4 T-lymphocyte activation in acute severe asthma. Am Rev Respir Dis. 1990;141:970-7.
10. Corrigan CJ, Haczku A, Gemou-Engesaeth V et al. T-lymphocyte activation in asthma is accompanied by increased serum concentrations in interleukin-5. Am Rev Respir Dis. 1993;147:540-7.
11. Cruz-Orive LM, Weibel ER. Sampling designs for stereology. J Microsc. 1981;122:235-57.
12. Cruz-Orive LM, Weibel ER. Recent stereological methods for cell biology: a brief survey. Am J Physiol. 1990;258:L148-56.
13. Fraser I, Doyle A, Hughes D, Gordon S. Use of surface molecules and receptors for studying macrophages and mononuclear phagocytes. J Immunol Methods. 1994;174: 95-102.
14. Geiser M, Baumann M, Cruz-Orive LM, Im Hof V, Waber U, Gehr P. The effect of particle inhalation on macrophage number and phagocytic activity in the intrapulmonary conducting airways of hamsters. Am J Respir Cell Mol Biol. 1994;10:594-603.
15. Geiser M, Serra AL, Cruz-Orive LM, Baumann M, Im Hof V, Gehr P. Efficiency of airway macrophage recovery by bronchoalveolar lavage in hamsters: a stereological approach. Eur Respir J. 1995;8:1712-8.
16. Gosset P, Tsicopoulos A, Wallaert B, Joseph M, Capron A, Tonnel AB. Tumor necrosis factor alpha and interleukin-6 production by human mononuclear phagocytes from allergic asthmatics after IgE-dependent stimulation. Am Rev Respir Dis. 1992;146:768-74.
17. Griffiths G, Warren G, Quinn P, Mathieu-Costello O, Hoppeler H. Density of newly synthesized plasma membrane proteins in intracellular membranes. I. Stereological studies. J Cell Biol. 1984;98:2133-41.
18. Gundersen HJG. Notes of the estimation of the numerical density of arbitrary profiles: the edge effect. J Microsc. 1977;11:219-23.
19. Gundersen HJG, Bendtsen TF, Korbo L et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis (review article). APMIS. 1988;96:379-94.
20. Helfgott DC, May LT, Sthoeger Z, Tamm I, Sehgal PB. Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts. J Exp Med. 1987;169:1300.
21. Horii Y, Muraguchi A, Suematsu S et al. Regulation of BSF-2/IL-6 production by human mononuclear cells: macrophage dependent synthesis of BSF-2/IL-6 by T cells. J Immunol. 1988;141:1529.
22. Im Hof V, Patrick G. Particle retention and clearance. J Aerosol Med. 1994;7:39-47.
23. Kahan BD. Cyclosporin. N Engl J Med. 1989;321:1725-38.
24. Kronke M, Leonard WJ, Depper JM et al. Cyclosporin A inhibits T-cell growth factor gene-expression at the level of mRNA transcription. Proc Natl Acad Sci USA. 1984;81: 5214-8.
25. Lehnert BE. Pulmonary and thoracic macrophage subpopulations and clearance of particles from the lung. Environ Health Perspect. 1992;97:17-46.
26. 59iron oxide with alveolar macrophages during alveolar clearance. Exp Lung Res. 1985;9:1-16.
27. Lock SH, Kay AB, Barnes NC. Double-blind, placebo-controlled study of Cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma. Am J Respir Crit Care Med. 1996;153:509-14.
28. Maye I, de Fraissinette A, Cruz-Orive LM, Vonderscher J, Richter F, Gehr P. Comparison of the rate of phagocytosis of orthorhombic cyclosporine A (CsA) and latex particles by alveolar macrophages from hamsters. Cell Mol Life Sci. 1997;53:689-96.
29. Pache JC, Roberts N, Vock P, Zimmermann A, Cruz-Orive LM. Vertical LM sectioning and parallel CT scanning designs for stereology: application to human lung. J Microsc. 1993;17:9-24.
30. Schauble TL, Boom WH, Finegan CK, Rich EA. Characterization of suppressor function of human alveolar macrophages for T lymphocyte responses to phytohemagglutinin: cellular selectivity, reversibility, and early events in T cell activation. Am J Respir Cell Mol Biol. 1993;8:89-97.
31. Warheit DB, Hartsky MA. Role of alveolar macrophage chemotaxis and phagocytosis in pulmonary clearance responses to inhaled particles: comparisons among rodent species. Microsc Res Tech. 1993;26:412-22.
32. Weibel ER. Stereology methods. Vol. 1. Practical methods for biological morphometry. London: Academic Press; 1979.