The effect of high glucocorticoid administration and food restriction on rodent skeletal muscle mitochondrial function and protein metabolism

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  You, Y Nancy ^a   Short, Kevin R ^a   Jourdan, Marion ^a   Klaus, Katherine A ^a   Walrand, Stephane ^a   Nair, K Sreekumaran ^a  

^a Mayo Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOACID DEHYDROGENASE; ADENOSINE TRIPHOSPHATE; BRANCHED CHAIN AMINO ACID; CYTOCHROME C OXIDASE; GLUCOCORTICOID; GLUCOSE; INSULIN; MALIC ACID; METHYLPREDNISOLONE; MITOCHONDRIAL PROTEIN; MYOSIN HEAVY CHAIN; PYRUVIC ACID; SODIUM CHLORIDE; MUSCLE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY MASS; CONTROLLED STUDY; DIET RESTRICTION; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME SYNTHESIS; FOOD INTAKE; MALE; MUSCLE MASS; MUSCLE MITOCHONDRION; NONHUMAN; OXIDATION; PLANTARIS MUSCLE; PROTEIN ANALYSIS; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RAT; SARCOPLASM; SKELETAL MUSCLE; SOLEUS MUSCLE; SPRAGUE DAWLEY RAT; WEIGHT REDUCTION; ANIMAL; BIOSYNTHESIS; BLOOD; BODY WEIGHT; CALORIC RESTRICTION; DOSE RESPONSE; GLUCOSE BLOOD LEVEL; METABOLISM; PHYSIOLOGY;

RATTUS; RODENTIA;

ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALORIC RESTRICTION; DOSE-RESPONSE RELATIONSHIP, DRUG; INSULIN; MALE; METHYLPREDNISOLONE; MITOCHONDRIA, MUSCLE; MUSCLE PROTEINS; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 65349195016     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005283     Document Type: Article

References (48)

1. Dardevet D, Sornet C, Taillandier d, Savary I, Attaix D, et al. (1995) Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. J Clin Invest 96: 2113-2119.
2. Rieu I, Sornet C, Grizard J, Dardevet D (2004) Glucocorticoid excess induces a prolonged leucine resistance on muscle protein synthesis in old rats. Exp Gerontol 39: 1315-21.
3. Hickson RC, Czerwinski SM, Wegrzyn LE (1995) Glutamine prevents downregulation of myosin heavy chain synthesis and muscle atrophy from glucocorticoids. Am J Physiol Endocrinol Metab 268: E730-4.
4. Czerwinski SM, Kurowski TG, O'Neill TM, Hickson RC (1987) Initiating regular exercise protects against muscle atrophy from glucocorticoids. J Appl Physiol 63: 1504-1510.
5. Czerwinski SM, Zak R, Kurowski TT, Falduto MT, Hickson RC (1989) Myosin heavy chain turnover and glucocorticoid deterrence by exercise in muscle. J Appl Physiol 67: 2311-2315.
6. Marone JR, Falduto MT, Essig DA, Hickson RC (1994) Effects of glucocorticoids and endurance training on cytochrome oxidase expression in skeletal muscle. J Appl Physiol 77: 1685-1690.
7. Minet-Quinard R, Moinard C, Walrand S, Villie F, Normand B, et al. (2000) Induction of a catabolic state in rats by dexamethasone: dose or time dependency? J Parenteral Enteral Nutr 24: 30-6.
8. Savary I, Debras E, Dardevet D, Sornet C, Capitan P, et al. (1998) Effect of glucocorticoid excess on skeletal and heart protein synthesis in adult and old rats. Br J Nutr 79: 297-304.
9. Kelly FJ, McGrath JA, Goldspink DF, Cullen MJ (1986) A morphological/ biochemical study of the actions of corticosteroids on rat skeletal muscle. Muscle Nerve 9: 1-10.
10. Dardevet D, Sornet C, Savary I, Debras E, Patureau-Mirand P, et al. (1998) Glucocorticoid effects on insulin- and IGF-I-regulated muscle protein metabolism during aging. J Endocrinol 156: 83-9.
11. Polla B, Bottinelli R, Sandoli D, Sardi C, Reggiani C (1994) Cortisone-induced changes in myosin heavy chain distribution in respiratory and hindlimb muscles. Acta Physiol Scand 151: 353-361.
12. Essen P, McPartlin JM, Wernerman J, Milne E, Vinnars E, et al. (1992) Short-term starvation decreases skeletal muscle protein synthesis in man. Clin Physiol 12: 287-299.
13. Magnusson K, Wahren J, Ekman L (1990) Protein synthesis in skeletal muscle during starvation and refeeding: comparison of data from intact muscle and muscle biopsy material. Metabolism 39: 1113-1117.
14. Bezaire V, Hofmann W, Kramer JK, Kozak LP, Harper ME (2001) Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice. Am J Physiol Endocrinol Metab 281: E975-82.
15. Koves TR, Li P, An J, Akimoto T, Slentz D, et al. (2005) Peroxisome proliferator-activated receptor-gamma co-activator 1 alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipidinduced mitochondrial inefficiency. J Biol Chem 280: 33588-98.
16. Barazzoni R, Zanetti M, Bosutti A, Biolo G, Vitali-Serdoz L, et al. (2005) Moderate caloric restriction, but not physiological hyperleptinemia per se, enhances mitochondrial oxidative capacity in rat liver and skeletal muscle-tissue-specific impact on tissue triglyceride content and AKT activation. Endocrinol 146: 2098-106.
17. Sreekumar R, Unnikrishnan J, Fu A, Nygren J, Short KR, et al. (2002) Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle. Am J Physiol Endocrinol Metab 283: 38-43.
18. Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, et al. (2002) Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418: 344-348.
19. Wibom R, Hagenfeldt L, von Dobeln U (2002) Measurement of ATP production and respiratory chain enzyme activities in mitochondria isolated from small muscle biopsy samples. Anal Biochem 311: 139-151.
20. 3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3. Am J Physiol Endocrinol Metab 280: E761-E769.
21. Wibom R, Lundin A, Hultman E (1990) A sensitive method for measuring ATPformation in rat muscle mitochondria. Scand J Clin Lab Invest 50: 143-152.
22. Robinson JB, Brent LG, Semgei B, Srere PA (1987) An enzymatic approach to the study of the Krebs tricarboxylic acid cycle. In: Darley-Usmar V, Rickwood D, Wilson MT, eds. Mitochondria. Oxford: IRL Press. pp 153-170.
23. Rooyackers OE, Balagopal P, Nair KS (1997) Measurement of synthesis rates of specific muscle proteins using needle biopsy samples. Muscle & Nerve 5 (suppl): S93-S96.
24. Balagopal P, Nair KS, Stirewalt WS (1994) Isolation of myosin heavy chain from small skeletal muscle samples by preparative continuous elution gel electrophoresis: Application to measurement of synthesis rate in humans and animal tissue. Anal Biochem 221: 72-77.
25. Balagopal P, Rooyackers OE, Adey DB, Ades PA, Nair KS (1997) Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol Endocrinol Metab 273: E790-E800.
26. Rooyackers OE, Adey DB, Ades PA, Nair KS (1996) Effect of age in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA 93: 15364-15369.
27. Ljungqvist O, Persson M, Ford GC, Nair KS (1997) Functional heterogeneity of leucine pools in human skeletal muscle. Am J Physiol 273: E564-E570.
28. Paulson JC, Deatherage FE (1954) Conditions for rapid hydrolysis of some proteins by Dowex 50 catalysis. J Amer Chem Soc 76: 6198-6200.
29. Fu A, Nair KS (1998) Age effect on fibrinogen and albumin synthesis in humans. Am J Physiol Endocrinol Metab 275: E1023-E1030.
30. Shimomura Y, Obayashi M, Murakami T, Harris RA (2001) Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branched-chain alpha-keto acid dehydrogenase kinase. Curr Opin Clin Nutr Metab Care 4: 419-23.
31. Aftring RP, Miller WJ, Buse MG (1988) Effects of diabetes and starvation on skeletal muscle branched-chain alpha-keto acid dehydrogenase activity. Am J Physiol Endocrinol Metab 254: E292-E300.
32. Cooper AJ, Conway M, Hutson SM (2002) A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases. Anal Biochem 308: 100-5.
33. Short KR, Nygren J, Nair KS (2007) Effect of T3-induced hyperthyroidism on mitochondrial and cytoplasmic protein synthesis rates in oxidative and glycolytic tissues in rats. Am J Physiol Endocrinol Metab 292: E642-E647.
34. Boirie Y, Short KR, Ahlman B, Charlton M, Nair KS (2001) Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin. Diabetes 50: 2652-2658.
35. Lieu FK, Powers SK, Herb RA, Criswell D, Martin D, et al. (1993) Exercise and glucocorticoid-induced diaphragmatic myopathy. J Appl Physiol 75: 763-71.
36. Duclos M, Gouarne C, Martin C, Rocher C, Mormede P, et al. (2004) Effects of corticosterone on muscle mitochondria identifying different sensitivity to glucocorticoids in Lewis and Fischer rats. Am J Physiol Endocrinol Metab 286: E159-67.
37. Weber K, Bruck P, Mikes Z, Kupper J, Klingenspor M, et al. (2002) Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle. Endocrinol 143: 177-184.
38. Mittendorfer B, Andersen JL, Plomgaard P, Saltin B, Babraj JA, et al. (2005) Protein synthesis rates in human muscles: neither anatomical location nor fibretype composition are major determinants. J Physiol 563: 203-11.
39. Quan ZY, Walser M (1991) Effect of corticosterone administration at varying levels on leucine oxidation and whole body protein synthesis and breakdown in adrenalectomized rats. Metabolism 40: 1263-7.
40. Emery PW, Sanderson P (1995) Effect of dietary restriction on protein synthesis and wound healing after surgery in the rat. Clin Sci 89: 383-8.
41. Sherwin RS (1978) Effect of starvation on the turnover and metabolic response to leucine. J Clin Invest. pp 1471-1481.
42. Mitch WE, Goldberg AL (1996) Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. N Engl J Med 335: 1897-1905.
43. Wing SS, Goldberg AL (1993) Glucocorticoids activate the ATP-ubiquitindependent proteolytic system in skeletal muscle during fasting. Am J Physiol 264: 668-676.
44. Beaufre're B, Horber FF, Schwenk WF, Marsh HM, Matthews D, et al. (1989) Glucocorticosteroids increase leucine oxidation and impair leucine balance in humans. Am J Physiol Endocrinol Metab 257: E712-E721.
45. Louard RJ, Bhushan R, Gelfand RA, Barrett EJ, Sherwin RS (1994) Glucocorticoids antagonize insulin's antiproteolytic action on skeletal muscle in humans. J Clin Endocrinol Metab 79: 278-284.
46. Short KR, Nygren J, Bigelow ML, Nair KS (2004) Effect of short-term prednisone use on blood flow, muscle protein metabolism, and function. J Clin Endocrinol Metab 89: 6198-6207.
47. Liu Z, Jahn LA, Long W, Fryburg DA, Wei L, et al. (2001) Branched chain amino acids activate messenger ribonucleic acid translation regulatory proteins in human skeletal muscle, and glucocorticoids blunt this action. J Clin Endocrinol Metab 86: 2136-2143.
48. Lofberg E, Gutierrez A, Wernerman J, Anderstam B, Mitch WE, et al. (2002) Effects of high doses of glucocorticoids on free amino acids, ribosomes and protein turnover in human muscle. Eur J Clin Invest 32: 345-53.