메뉴 건너뛰기




Volumn 44, Issue 3, 2009, Pages 386-394

Cigarette smoke condensate stimulates urokinase production through the generation of reactive oxygen species and activation of the mitogen activated protein kinase pathways in human gingival fibroblasts

Author keywords

Cigarette; Fibroblasts; Mitogen activated protein kinase; Reactive oxygen species; Urokinase

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PLASMIN; REACTIVE OXYGEN METABOLITE; UROKINASE;

EID: 65349194441     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2008.01114.x     Document Type: Article
Times cited : (10)

References (50)
  • 1
    • 0034183096 scopus 로고    scopus 로고
    • Smoking-attributible periodontitis in the United States. Findings from NHANES III. National Health and Nutritional Examination Survey
    • Tomar SL, Asma S. Smoking-attributible periodontitis in the United States. Findings from NHANES III. National Health and Nutritional Examination Survey. J Periodontol 2000 71 : 743 751.
    • (2000) J Periodontol , vol.71 , pp. 743-751
    • Tomar, S.L.1    Asma, S.2
  • 2
    • 0038315269 scopus 로고    scopus 로고
    • Tobacco smoking and risk for periodontal disease
    • DOI 10.1034/j.1600-051X.2003.00272.x
    • Bergstrom J. Tobacco smoking and risk for periodontal disease. J Clin Periodontol 2003 30 : 107 113. (Pubitemid 38019404)
    • (2003) Journal of Clinical Periodontology , vol.30 , Issue.2 , pp. 107-113
    • Bergstrom, J.1
  • 3
    • 34247631302 scopus 로고    scopus 로고
    • The impact of cigarette smoking on periodontal disease and treatment
    • Johnson GK, Guthmiller JM. The impact of cigarette smoking on periodontal disease and treatment. Periodontol 2000 2007 44 : 178 194.
    • (2007) Periodontol 2000 , vol.44 , pp. 178-194
    • Johnson, G.K.1    Guthmiller, J.M.2
  • 4
    • 34248575640 scopus 로고    scopus 로고
    • Smoking interferes with the prognosis of dental implant treatment: A systematic review and meta-analysis
    • Strietzel FP, Reichart PA, Kale A, Kulkarni M, Wegner B, Küchler I. Smoking interferes with the prognosis of dental implant treatment: a systematic review and meta-analysis. J Clin Periodontol 2007 34 : 523 544.
    • (2007) J Clin Periodontol , vol.34 , pp. 523-544
    • Strietzel, F.P.1    Reichart, P.A.2    Kale, A.3    Kulkarni, M.4    Wegner, B.5    Küchler, I.6
  • 8
    • 0031602248 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of the plasminogen activator system in human gingival tissues and gingival fibroblasts
    • Xiao Y, Bunn CL, Bartold PM. Immunohistochemical demonstration of the plasminogen activator system in human gingival tissues and gingival fibroblasts. J Periodontal Res 1998 33 : 17 26. (Pubitemid 128529547)
    • (1998) Journal of Periodontal Research , vol.33 , Issue.1 , pp. 17-26
    • Xiao, Y.1    Bunn, C.L.2    Bartold, P.M.3
  • 9
    • 33744825704 scopus 로고    scopus 로고
    • Differential uPA expression by TGF-β1 in gingival fibroblasts
    • Smith PC, Martínez J. Differential uPA expression by TGF-β1 in gingival fibroblasts. J Dent Res 2006 85 : 150 155.
    • (2006) J Dent Res , vol.85 , pp. 150-155
    • Smith, P.C.1    Martínez, J.2
  • 10
    • 0033385667 scopus 로고    scopus 로고
    • Localization of plasminogen activators and plasminogen-activator inhibitors in human gingival tissues demonstrated by immunohistochemistry and in situ hybridization
    • DOI 10.1016/S0003-9969(99)00098-9, PII S0003996999000989
    • Kinnby B, Lindberg P, Lecander I, Matsson L. Localization of plasminogen activators and plasminogen inhibitors in human gingival tissues by immunohistochemistry and in situ hybridization. Arch Oral Biol 1999 44 : 1027 1034. (Pubitemid 30029577)
    • (1999) Archives of Oral Biology , vol.44 , Issue.12 , pp. 1027-1034
    • Kinnby, B.1    Lindberg, P.2    Lecander, I.3    Matsson, L.4
  • 12
    • 0034797402 scopus 로고    scopus 로고
    • Differential effects of acute and chronic wound fluids on urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor, and tissue-type plasminogen activator in cultured human keratinocytes and fibroblasts
    • DOI 10.1046/j.1524-475X.2001.00314.x
    • Weckroth M, Vaheri A, Myöhänen H, Tukiainen E, Sirén V. Differential effects of acute and chronic wound fluids on urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor, and tissue-type plasminogen activator in cultured human keratinocytes and fibroblasts. Wound Repair Regen 2001 9 : 314 322. (Pubitemid 32954895)
    • (2001) Wound Repair and Regeneration , vol.9 , Issue.4 , pp. 314-322
    • Weckroth, M.1    Vaheri, A.2    Myohanen, H.3    Tukiainen, E.4    Siren, V.5
  • 14
    • 33646502568 scopus 로고    scopus 로고
    • Effect of smoking on crevicular polymorphonuclear neutrophil function in periodontally healthy subjects
    • Guntsch A, Erler M, Preshaw PM, Sigusch BW, Klinger G, Glockmann E. Effect of smoking on crevicular polymorphonuclear neutrophil function in periodontally healthy subjects. J Periodontal Res 2006 41 : 184 188.
    • (2006) J Periodontal Res , vol.41 , pp. 184-188
    • Guntsch, A.1    Erler, M.2    Preshaw, P.M.3    Sigusch, B.W.4    Klinger, G.5    Glockmann, E.6
  • 15
    • 2342529820 scopus 로고    scopus 로고
    • Smoking cessation increases gingival blood flow and gingival crevicular fluid
    • DOI 10.1111/j.1600-051X.2004.00476.x
    • Morozumi T, Kubota T, Sato T, Okuda K, Yoshie H. Smoking cessation increases gingival blood flow and gingival crevicular fluid. J Clin Periodontol 2004 31 : 267 272. (Pubitemid 38623957)
    • (2004) Journal of Clinical Periodontology , vol.31 , Issue.4 , pp. 267-272
    • Morozumi, T.1    Kubota, T.2    Sato, T.3    Okuda, K.4    Yoshie, H.5
  • 16
    • 0029555892 scopus 로고
    • The effect of D-x03B1;-tocopherol on the production of extracellular matrix proteins and prostaglandin by human mesangial cells
    • Tipton DA, Dabbous MK. Effects of nicotine on proliferation and extracellular matrix production of human gingival fibroblasts in vitro. J Periodontol 1995 66 : 1056 1064. (Pubitemid 26141812)
    • (1995) Journal of the Japan Diabetes Society , vol.38 , Issue.11 , pp. 901-904
    • Tada, H.1    Kawai, H.2    Ishii, H.3    Isogai, S.4
  • 17
    • 0036675480 scopus 로고    scopus 로고
    • Effect of cigarette smoking on human PDL fibroblasts attachment to periodontally involved root surfaces in vitro
    • DOI 10.1034/j.1600-051X.2002.290814.x
    • Gamal AY, Bayomy MM. Effect of cigarette smoking on human PDL fibroblasts attachment to periodontally involved root surfaces in vitro. J Clin Periodontol 2002 29 : 763 770. (Pubitemid 41697818)
    • (2002) Journal of Clinical Periodontology , vol.29 , Issue.8 , pp. 763-770
    • Gamal, A.Y.1    Bayomy, M.M.2    Garnick, J.J.3
  • 18
    • 0033929138 scopus 로고    scopus 로고
    • Effects of nicotine on the strength of attachment of gingival fibroblasts to glass and non-diseased human root surfaces
    • Tanur E, McQuade MJ, McPherson JC, AlHashimi IH, Rivera-Hidalgo F. Effects of nicotine on the strength of attachment of gingival fibroblasts to glass and non-diseased human root surfaces. J Periodontol 2000 71 : 717 722. (Pubitemid 30483540)
    • (2000) Journal of Periodontology , vol.71 , Issue.5 , pp. 717-722
    • Tanur, E.1    McQuade, M.J.2    McPherson, J.C.3    Al-Hashimi, I.H.4    Rivera-Hidalgo, F.5
  • 19
    • 0642280644 scopus 로고    scopus 로고
    • Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate
    • DOI 10.1385/CT:3:2:101
    • Nordskog BK, Blixt AD, Morgan WT, Fields WR, Hellman GM. Matrix degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. Cardiovasc Toxicol 2003 3 : 101 117. (Pubitemid 41490358)
    • (2003) Cardiovascular Toxicology , vol.3 , Issue.2 , pp. 101-117
    • Nordskog, B.K.1    Blixt, A.D.2    Morgan, W.T.3    Fields, W.R.4    Hellmann, G.M.5
  • 20
    • 0030475673 scopus 로고    scopus 로고
    • Nicotine and cotinine stimulate secretion of basic fibroblast growth factor and affect expression of matrix metalloproteinases in cultured human smooth muscle cells
    • DOI 10.1016/S0741-5214(96)70038-1
    • Carty CS, Soloway PD, Kayastha S et al. Nicotine and cotinine stimulate secretion of basic fibroblast growth factor and affect expression of matrix metalloproteinases in cultured human smooth muscle cells. J Vasc Surg 1996 24 : 927 934. (Pubitemid 26425697)
    • (1996) Journal of Vascular Surgery , vol.24 , Issue.6 , pp. 927-935
    • Carty, C.S.1    Soloway, P.D.2    Kayastha, S.3    Bauer, J.4    Marsan, B.5    Ricotta, J.J.6    Dryjski, M.7    Cohen, J.R.8    Pappas, P.J.9
  • 21
    • 33947683135 scopus 로고    scopus 로고
    • Nicotine increases the collagen-degrading ability of human gingival fibroblasts
    • Zhou JB, Olson L, Windsor J. Nicotine increases the collagen-degrading ability of human gingival fibroblasts. J Periodontal Res 2007 42 : 228 235.
    • (2007) J Periodontal Res , vol.42 , pp. 228-235
    • Zhou, J.B.1    Olson, L.2    Windsor, J.3
  • 22
    • 0032779652 scopus 로고    scopus 로고
    • Longitudinal effect of non-surgical treatment and systemic metronidazole for 1 week in smokers and non-smokers with refractory periodontitis: A 5- year study
    • DOI 10.1902/jop.1999.70.7.761
    • Soder B. Neutrophil elastase activity, levels of prostaglandin E2 and matrix metalloproteinase-8 in refractory periodontitis sites in smokers and non-smokers. Acta Odontol Scand 1999 57 : 77 82. (Pubitemid 29340772)
    • (1999) Journal of Periodontology , vol.70 , Issue.7 , pp. 761-771
    • Soder, B.1    Nedlich, U.2    Jian Jin, L.3
  • 23
    • 0142171650 scopus 로고    scopus 로고
    • Active and passive smoking
    • In. Marquardt, H. Schaefer, S.G. McClellan, R. Welsch, F. eds. New York. Academic Press
    • Hoffmann D, Wynder EL. Active and passive smoking. In : Marquardt H, Schaefer SG, McClellan R, Welsch F, eds. Toxicology. New York : Academic Press, 1999 : 879 898.
    • (1999) Toxicology. , pp. 879-898
    • Hoffmann, D.1    Wynder, E.L.2
  • 24
    • 0032622501 scopus 로고    scopus 로고
    • Effects of nicotine on periodontal ligament fibroblasts in vitro
    • Giannopoulou C, Geinoz A, Cimasoni G. Effects of nicotine on periodontal ligament fibroblasts in vitro. J Clin Periodontol 1999 26 : 49 55.
    • (1999) J Clin Periodontol , vol.26 , pp. 49-55
    • Giannopoulou, C.1    Geinoz, A.2    Cimasoni, G.3
  • 25
    • 0033565976 scopus 로고    scopus 로고
    • Deregulation of the signaling pathways controlling urokinase production: Its relationship with the invasive phenotype
    • DOI 10.1046/j.1432-1327.1999.00507.x
    • Aguirre-Guiso JA, Alonso DF, Farias EF, Gomez DE, de Kier Joffè EB. Deregulation of signaling pathways controlling urokinase production. Its relationship with the invasive phenotype. Eur J Biochem 1999 263 : 295 304. (Pubitemid 29337018)
    • (1999) European Journal of Biochemistry , vol.263 , Issue.2 , pp. 295-304
    • Aguirre Ghiso, J.A.1    Alonso, D.F.2    Farias, E.F.3    Gomez, D.E.4    Bal De Kier Joffe, E.5
  • 26
    • 0034663060 scopus 로고    scopus 로고
    • The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG
    • Parra M, Lluis F, Miralles F, Caelles C, Muñoz-Cánoves P. The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG. Blood 2000 96 : 1415 1424. (Pubitemid 30658472)
    • (2000) Blood , vol.96 , Issue.4 , pp. 1415-1424
    • Parra, M.1    Lluis, F.2    Miralles, F.3    Caelles, C.4    Munoz-Canoves, P.5
  • 27
    • 0024485092 scopus 로고
    • Characterization of one phenotype of human periodontal granulation-tissue fibroblasts
    • Larjava H, Heino J, Kähäri V-M, Vuorio E. Characterization of one phenotype of human periodontal granulation-tissue fibroblasts. J Dent Res 1989 68 : 20 25.
    • (1989) J Dent Res , vol.68 , pp. 20-25
    • Larjava, H.1    Heino, J.2    Kähäri, V.-M.3    Vuorio, E.4
  • 28
    • 0034806972 scopus 로고    scopus 로고
    • Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress
    • DOI 10.1128/MCB.21.20.6913-6926.2001
    • Benhar M, Dalyot I, Engelberg D, Levitzki A. Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol Cell Biol 2001 20 : 6913 6926. (Pubitemid 32911252)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.20 , pp. 6913-6926
    • Benhar, M.1    Dalyot, I.2    Engelberg, D.3    Levitzki, A.4
  • 29
    • 17744414013 scopus 로고    scopus 로고
    • Bone extracellular matrix stimulates invasiveness of estrogen-responsive human mammary MCF-7 cells
    • DOI 10.1002/(SICI)1097-0215(19991008)83:2<278::AID-IJC21>3.0.CO;2-7
    • Martinez J, Fuentes M, Cambiazo V, Santibañez JF. Bone extracellular matrix stimulates invasiveness of estrogen-responsive human mammary MCF-7 cells. Int J Cancer 1999 83 : 278 282. (Pubitemid 29449109)
    • (1999) International Journal of Cancer , vol.83 , Issue.2 , pp. 278-282
    • Martinez, J.1    Fuentes, M.2    Cambiazo, V.3    Santibanez, J.F.4
  • 30
    • 0029150849 scopus 로고
    • The secretion of urokinase-like plasminogen activator is inhibited by microtubule-interacting drugs
    • Santibañez JF, Maccioni RB, Martínez J. The secretion of urokinase-like plasminogen activator is inhibited by microtubule-interacting drugs. Cell Biochem Funct 1995 13 : 217 225.
    • (1995) Cell Biochem Funct , vol.13 , pp. 217-225
    • Santibañez, J.F.1    MacCioni, R.B.2    Martínez, J.3
  • 32
    • 0032808221 scopus 로고    scopus 로고
    • Temporal expression of urokinase plasminogen activator, plasminogen activator inhibitor and gelatinase-B in chronic wound fluid switches from a chronic to acute wound profile with progression to healing
    • DOI 10.1046/j.1524-475X.1999.00154.x
    • Wysocki AB, Kusakabe AO, Chang S, Tuan TL. Temporal expression of urokinase plasminogen activator, plasminogen activator inhibitor and gelatinase-B in chronic wound fluid switches from a chronic to acute wound profile with progression to healing. Wound Repair Regen 1999 7 : 154 165. (Pubitemid 29331919)
    • (1999) Wound Repair and Regeneration , vol.7 , Issue.3 , pp. 154-165
    • Wysocki, A.B.1    Kusakabe, A.O.2    Chang, S.3    Tuan, T.-L.4
  • 34
    • 0038623222 scopus 로고    scopus 로고
    • Relationship between fibrinolytic activity and gingival inflammatory reaction in young individuals
    • DOI 10.1034/j.1600-0765.2003.01370.x
    • Olofsson A, Lindberg P, Lanke J, Matsson L, Kinnby B. Relationship between fibrinolytic activity and gingival inflammatory reaction in young individuals. J Periodontal Res 2003 38 : 104 108. (Pubitemid 37463604)
    • (2003) Journal of Periodontal Research , vol.38 , Issue.1 , pp. 104-108
    • Olofsson, A.1    Lindberg, P.2    Lanke, J.3    Matsson, L.4    Kinnby, B.5
  • 35
    • 33644987494 scopus 로고    scopus 로고
    • Gingival tissue and crevicular fluid co-operation in adult periodontitis
    • Beklen A, Tüter G, Sorsa T et al. Gingival tissue and crevicular fluid co-operation in adult periodontitis. J Dent Res 2006 85 : 59 63.
    • (2006) J Dent Res , vol.85 , pp. 59-63
    • Beklen, A.1    Tüter, G.2    Sorsa, T.3
  • 39
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
    • DOI 10.1038/nrm2256, PII NRM2256
    • D'Autreaux B, Toledano MB. ROS as signaling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 2007 8 : 813 824. (Pubitemid 47462134)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 813-824
    • D'Autreaux, B.1    Toledano, M.B.2
  • 40
    • 18144383207 scopus 로고    scopus 로고
    • PTPs versus PTKs: The redox side of the coin
    • DOI 10.1080/10715760400027987
    • Chiarugi P. PTPs versus PTKs: The redox side of the coin. Free Radic Res 2005 39 : 353 364. (Pubitemid 40613714)
    • (2005) Free Radical Research , vol.39 , Issue.4 , pp. 353-364
    • Chiarugi, P.1
  • 41
    • 25444480482 scopus 로고    scopus 로고
    • Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells
    • DOI 10.1186/rr172
    • Hellermann GR, Nagy SB, Kong X, Lockey RF, Mohapatra SS. Mechanism of cigarette smoke condensate-induced inflammatory response in human bronchial epithelial cells. Respir Res 2002 3 : 22 29. (Pubitemid 41358114)
    • (2002) Respiratory Research , vol.3 , pp. 22
    • Hellermann, G.R.1    Nagy, S.B.2    Kong, X.3    Lockey, R.F.4    Mohapatra, S.S.5
  • 42
    • 2342644797 scopus 로고    scopus 로고
    • Extracellular Regulated Kinase/Mitogen Activated Protein Kinase Is Up-regulated in Pulmonary Emphysema and Mediates Matrix Metalloproteinase-1 Induction by Cigarette Smoke
    • DOI 10.1074/jbc.M313842200
    • Mercer BA, Kolesnikova N, Soneto J, D'Armiento J. Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. J Biol Chem 2004 279 : 17690 17296. (Pubitemid 38568101)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.17 , pp. 17690-17696
    • Mercer, B.A.1    Kolesnikova, N.2    Sonett, J.3    D'Armiento, J.4
  • 44
    • 0038697896 scopus 로고    scopus 로고
    • N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-B deoxyribonucleic acid-binding activity in human fetal membranes in Vitro
    • DOI 10.1210/jc.2002-021677
    • Lappas M, Permezel M, Rice GE. N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J Clin Endocrinol Metab 2003 88 : 1723 1729. (Pubitemid 36623395)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.4 , pp. 1723-1729
    • Lappas, M.1    Permezel, M.2    Rice, G.E.3
  • 45
    • 27144501470 scopus 로고    scopus 로고
    • Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of Janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells
    • DOI 10.1158/0008-5472.CAN-05-0598
    • Kim MH, Cho HS, Jung M et al. Extracellular signal-regulated kinase and AP-1 pathways are involved in reactive oxygen species-induced urokinase plasminogen activator receptor expression in human gastric cancer cells. Int J Oncol 2005 26 : 1669 1674. (Pubitemid 41507978)
    • (2005) Cancer Research , vol.65 , Issue.20 , pp. 9159-9163
    • Shida, D.1    Kitayama, J.2    Mori, K.3    Watanabe, T.4    Nagawa, H.5
  • 46
    • 0031127439 scopus 로고    scopus 로고
    • Stimulation of plasminogen activator/plasmin system in gingival fibroblast cells by oxygen radicals
    • DOI 10.1016/S0003-9969(97)00010-1, PII S0003996997000101
    • Tanaka F, Ogura N, Abiko Y. Stimulation of plasminogen activator/plasmin system in gingival fibroblast cells by oxygen radicals. Arch Oral Biol 1997 42 : 263 270. (Pubitemid 27270845)
    • (1997) Archives of Oral Biology , vol.42 , Issue.4 , pp. 263-270
    • Tanaka, F.1    Ogura, N.2    Abiko, Y.3
  • 47
    • 0029133267 scopus 로고
    • Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts
    • Besser D, Presta M, Nagamine Y. Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts. Cell Growth Differ 1995 6 : 1009 1017.
    • (1995) Cell Growth Differ , vol.6 , pp. 1009-1017
    • Besser, D.1    Presta, M.2    Nagamine, Y.3
  • 49
    • 3042753807 scopus 로고    scopus 로고
    • MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription
    • DOI 10.1182/blood-2003-08-2661
    • Benasciutti E, Pagès G, Kenzior O, Folk W, Blasi F, Crippa MP. MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription. Blood 2004 104 : 256 262. (Pubitemid 38879866)
    • (2004) Blood , vol.104 , Issue.1 , pp. 256-262
    • Benasciutti, E.1    Pages, G.2    Kenzior, O.3    Folk, W.4    Blasi, F.5    Crippa, M.P.6
  • 50
    • 8744252318 scopus 로고    scopus 로고
    • Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin
    • DOI 10.1111/j.1600-0765.2004.00753.x
    • Smith PC, Santibañez JF, Morales JP, Martinez J. Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin. J Periodontal Res 2004 39 : 380 387. (Pubitemid 39523882)
    • (2004) Journal of Periodontal Research , vol.39 , Issue.6 , pp. 380-387
    • Smith, P.C.1    Santibanez, J.F.2    Morales, J.P.3    Martinez, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.