Effect of quercetin on the gene expression profile of the Mouse intestine

Bioscience, Biotechnology and Biochemistry

Volumn 73, Issue 3, 2009, Pages 722-725

  Natsume, Yayoi ^a   Kadota, Koji ^a   Satsu, Hideo ^a   Shimizu, Makoto ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Dose dependence; Gene expression profile; Intestine; Quercetin

Indexed keywords

AFFYMETRIX; BALB/C MOUSE; DOSE-DEPENDENCE; GENE EXPRESSION PROFILE; INTESTINE; LOW DOSE; MICROARRAY ANALYSIS; MOUSE GENOMES; NEGATIVE CONTROLS; QUERCETIN; SMALL INTESTINES;

BIOACTIVITY; CLUSTER ANALYSIS; GENE EXPRESSION; PHENOLS;

FATTY ACIDS;

MESSENGER RNA; QUERCETIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CLUSTER ANALYSIS; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; INTESTINE; MALE; METABOLISM; MOUSE;

ANIMALS; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTESTINES; MALE; MICE; MICE, INBRED BALB C; QUERCETIN; RNA, MESSENGER;

MUS;

EID: 65349194438     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80484     Document Type: Article

References (7)

1. Williamson, G., and Manach, C, Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am. J. Clin. Nutr., 81, 243S-255S (2005).
2. Perez-Vizcaino, F., Duarte, J., and Andriantsitohaina, R., Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols. Free Radic. Res., 40, 1054-1065 (2006).
3. Lipshutz, R. J., Fodor, S. P., Gingeras, T. R., and Lockhart, D. J., High density synthetic oligonucleotide arrays. Nat. Genet., 21, 20-24 (1999).
4. Li, C, and Wong, W. H., Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl. Acad. Sci USA, 98, 31-36 (2001).
5. Hong, Y. J., and Mitchell, A. E., Identification of glutathione-related quercetin metabolites in humans. Chem. Res. Toxicol., 19, 1525-1532 (2006).
6. Nies, A. T., and Keppler, D., The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch., 453, 643-659 (2007).
7. Bock, K. W., Eckle, T., Ouzzine, M., and Fournel-Gigleux, S., Coordinate induction by antioxidants of UDP-glucuronosyltrans-ferase UGT1A6 and the apical conjugate export pump MRP2 (multidrug resistance protein 2) in Caco-2 cells. Biochem. Pharmacol., 59, 467-470 (2000). 8) van Zanden, J. J., Geraets, L., Wortelboer, H. M., van Bladeren, P. J., Rietjens, I. M., and Cnubben, N. H., Structural requirements for the flavonoid-mediated modulation of glutathione S-trans-ferase Pl-1 and GS-X pump activity in MCF7 breast cancer cells. Biochem. Pharmacol, 67, 1607-1617 (2004).