Gastric leiomyosarcoma manifesting peculiar findings: Radiological- pathological correlation

Pathology International

Volumn 59, Issue 5, 2009, Pages 306-311

  Masuzawa, Naoko ^a,b   Kishimoto, Mitsuo ^a   Nishimura, Ayako ^a   Ichiba, Noriatsu ^a   Aoki, Etsuo ^a   Yanagibashi, Ken ^b   Hirota, Seiichi ^c   Yanagisawa, Akio ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b OTSU MUNICIPAL HOSPITAL   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

C kit; In vitro magnetic resonance imaging; Leiomyosarcoma; Radiological pathological correlation; Stomach

Indexed keywords

COMPLEMENTARY DNA; DESMIN;

ADULT; ARTICLE; CASE REPORT; CYTOPLASM; EXON; FEMALE; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LEIOMYOSARCOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH SARCOMA; TUMOR CELL;

ADULT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LEIOMYOSARCOMA; MAGNETIC RESONANCE IMAGING; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELL FACTOR; STOMACH NEOPLASMS;

EID: 65349173561     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2009.02370.x     Document Type: Article

References (19)

1. Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Esophageal stromal tumors: A clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 2000 24 : 211 22.
2. Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Gastrointestinal stromal tumors and leiomyosarcomas in the colon: A clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. Am J Surg Pathol 2000 24 : 1339 52.
3. Miettinen M, Furlong M, Sarlomo-Rikala M, Burke A, Sobin LH, Lasota J. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the rectum and anus: A clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J Surg Pathol 2001 25 : 1121 33.
4. Miettinen M, Kopczynski J, Makhlouf HR et al. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the duodenum: A clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases. Am J Surg Pathol 2003 27 : 625 41.
5. Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol 2005 29 : 52 68.
6. Miettinen M, Fetsch JF. Evaluation of biological potential of smooth muscle tumours. Histopathology 2006 48 : 97 105.
7. Agaimy A, Wünsh PH. True smooth muscle neoplasms of the gastrointestinal tract: Morphological spectrum and classification in a series of 85 cases from a single institute. Langenbecks Arch Surg 2007 392 : 75 81.
8. Furitsu T, Tsujimura T, Tono T et al. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 1993 92 : 1736 44.
9. Hirota S, Ohashi A, Nishida T et al. Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors. Gastroenterology 2003 125 : 660 67.
10. Fletcher CDM, Berman JJ, Corless C et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002 33 : 459 65.
11. Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Mod Pathol 2000 13 : 1134 42.
12. Weiss SW, Goldblum JR. Leiomyosarcoma. In : Weiss SW, Goldblum JR, eds. Enzinger and Weiss's Soft Tissue Tumors, 5th edn. St Louis : Mosby, 2008 545 64.
13. Takahashi Y, Shimizu S, Ishida T et al. Plexiform angiomyxoid myofibroblastic tumor of the stomach. Am J Surg Pathol 2007 31 : 724 8.
14. Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998 279 : 577 80.
15. Heinrich MC, Corless CL, Duensing A et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003 299 : 708 10.
16. Lasota J, Jasinski M, Sarlomo-Rikala M, Miettinen M. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol 1999 154 : 53 60.
17. Thickman DI, Kundel HL, Wolf G. Nuclear magnetic resonance characteristics of fresh and fixed tissue: The effect of elapsed time. Radiology 1983 148 : 183 5.
18. Imai Y, Kressel HY, Saul SH et al. Colorectal tumors: An in vitro study of high-resolution MR imaging. Radiology 1990 177 : 695 701.
19. Auh YH, Lim TH, Lee DH et al. In vitro MR imaging of the resected stomach with a 4.7-T superconducting magnet. Radiology 1994 191 : 129 34.