Effect of r219k polymorphism of the abca1 gene on the lipid-lowering effect of pravastatin in chinese patients with coronary heart disease

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 5-6, 2009, Pages 567-570

  Li, Jia ^a   Wang, Lan Feng ^a   Li, Zhu Qin ^a   Pan, Wei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reducatse inhibitor; ATP binding cassette transporter A1 (ABCA1); Coronary heart disease; Genetic polymorphism

Indexed keywords

ABC TRANSPORTER A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; PRAVASTATIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CHINESE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; ISCHEMIC HEART DISEASE; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; AMINO ACID SUBSTITUTION; ARGININE; ASIAN CONTINENTAL ANCESTRY GROUP; ATP-BINDING CASSETTE TRANSPORTERS; CORONARY DISEASE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPOLIPIDEMIC AGENTS; LIPIDS; LYSINE; MALE; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PRAVASTATIN; TREATMENT OUTCOME;

EID: 65349162401     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.05119.x     Document Type: Article

References (28)

1. Fu R, Sun YM, Su Y, Wu Y, Luan Y. The effect of statin therapy on plasma high-density lipoprotein cholesterol levels is modified by paraoxonase 1 in Chinese patients with coronary heart disease. Clin. Exp. Pharmacol. Physiol. 2008 35 : 982 3.
2. McCaskie PA, Beilby JP, Chapman CM et al. Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease. Hum. Genet. 2007 121 : 401 11. (Pubitemid 46554676)
3. Benton JL, Ding J, Tsai MY et al. Associations between two common polymorphisms in the ABCA1 gene and subclinical atherosclerosis: Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2007 193 : 352 60. (Pubitemid 47058097)
4. Wang N, Tall AR. Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux. Arterioscler. Thromb. Vasc. Biol. 2003 23 : 1178 84. (Pubitemid 36871270)
5. Kothare PA, Linnebjerg H, Skrivanek Z et al. Exenatide effects on statin pharmacokinetics and lipid response. Int. J. Clin. Pharmacol. Ther. 2007 45 : 114 20. (Pubitemid 46344143)
6. 2. Arterioscler. Thromb. Vasc. Biol. 2008 28 : 1200 6.
7. Chan DC, Watts GF. Pharmacological regulation of dyslipoproteinaemia in insulin resistant states. Curr. Vasc. Pharmacol. 2008 6 : 67 77.
8. Palmer LJ, Cookson WO. Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma. Respir. Res. 2001 2 : 102 12. (Pubitemid 34187914)
9. Donaldson PT. Genetics of liver disease: Immunogenetics and disease pathogenesis. Gut 2004 53 : 599 608. (Pubitemid 38372988)
10. Frikke-Schmidt R, Nordestgaard BG, Stene MC et al. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA 2008 299 : 2524 32.
11. Ergen A, Isbir S, Tekeli A, Isbir T. Investigation of ABCA1 C69T and G-191C polymorphisms in coronary artery disease. In Vivo 2008 22 : 187 90.
12. Kyriakou T, Pontefract DE, Viturro E et al. Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients. Hum. Mol. Genet. 2007 16 : 1412 22. (Pubitemid 47061338)
13. Harada T, Imai Y, Nojiri T et al. A common Ile 823 Met variant of ATP-binding cassette transporter A1 gene (ABCA1) alters high density lipoprotein cholesterol level in Japanese population. Atherosclerosis 2003 169 : 105 12. (Pubitemid 36830928)
14. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 1971 18 : 499 502.
15. Saleheen D, Khanum S, Haider SR et al. A novel haplotype in ABCA1 gene effects plasma HDL-C concentration. Int. J. Cardiol. 2007 115 : 7 13.
16. Mott S, Yu L, Marcil M, Boucher B, Rondeau C, Genest Jr. J. Decreased cellular cholesterol efflux is a common cause of familial hypoalphalipoproteinemia: Role of the ABCA1 gene mutations. Atherosclerosis 2000 152 : 457 68.
17. Brooks-Wilson A, Marcil M, Clee SM et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat. Genet. 1999 22 : 336 45. (Pubitemid 29369523)
18. Clee SM, Zwinderman AH, Engert JC et al. Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation 2001 103 : 1198 205. (Pubitemid 32221340)
19. Yamakawa-Kobayashi K, Yanagi H, Yu Y, Endo K, Arinami T, Hamaguchi H. Associations between serum high-density lipoprotein cholesterol or apolipoprotein AI levels and common genetic variants of the ABCA1 gene in Japanese school-aged children. Metabolism 2004 53 : 182 6. (Pubitemid 38168889)
20. Soro-Paavonen A, Naukkarinen J, Lee-Rueckert M et al. Common ABCA1 variants, HDL levels, and cellular cholesterol efflux in subjects with familial low HDL. J. Lipid Res. 2007 48 : 1409 16. (Pubitemid 47312044)
21. Evans D, Beil FU. The association of the R219K polymorphism in the ATP-binding cassette transporter 1 (ABCA1) gene with coronary heart disease and hyperlipidaemia. J. Mol. Med. 2003 81 : 264 70. (Pubitemid 36578925)
22. Zwarts KY, Clee SM, Zwinderman AH et al. ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels. Clin. Genet. 2002 61 : 115 25. (Pubitemid 36372616)
23. Huang W, Moriyama K, Koga T et al. Novel mutations in ABCA1 gene in Japanese patients with Tangier disease and familial high density lipoprotein deficiency with coronary heart disease. Biochem. Biophys. Acta 2001 1537 : 71 8. (Pubitemid 32710042)
24. Rust S, Rosier M, Funke H et al. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat. Genet. 1999 22 : 352 5. (Pubitemid 29369525)
25. Tall AR, Costet P, Wang N. Regulation and mechanisms of macrophage cholesterol efflux. J. Clin. Invest. 2002 110 : 899 904.
26. Tall AR. Metabolic and genetic control of HDL cholesterol levels. J. Intern. Med. 1992 231 : 661 8.
27. McNeish J, Aiello RJ, Guyot D et al. High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. Proc. Natl Acad. Sci. USA 2000 97 : 4245 50. (Pubitemid 30226118)
28. Orso E, Broccardo C, Kaminski WE et al. Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and ABCA1-deficient mice. Nat. Genet. 2000 24 : 192 6. (Pubitemid 30094724)