Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 10, 2009, Pages 2627-2629

  Kamath, Vivekanand P ^a   Xue, Jie ^a   Juarez Brambila, Jesus J ^a  

^a BIOCRYST PHARMACEUTICALS INC   (United States)

Author keywords

PNP inhibitor; T cell proliferation

Indexed keywords

FORODESINE; FORODESINE DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; REACTION ANALYSIS; STEREOISOMERISM; STRUCTURE ANALYSIS;

CELL PROLIFERATION; ENZYME INHIBITORS; HUMANS; PURINE NUCLEOSIDES; PURINE-NUCLEOSIDE PHOSPHORYLASE; PYRIMIDINONES; T-LYMPHOCYTES;

EID: 65349161620     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.04.018     Document Type: Article

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19. +): 267.1082; found: 267.1080.
20. +): 267.1082; found: 267.1085.
21. +): 267.1082; found: 267.1081.