Chronic lymphocytic leukemia with t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated With atypical morphologic features and unmutated IgV H genes

American Journal of Clinical Pathology

Volumn 131, Issue 5, 2009, Pages 663-670

  Yin, C Cameron ^a,c   Lin, Katherine I Chun ^a   Ketterling, Rhett P ^a   Knudson, Ryan A ^a   Medeiros, L Jeffrey ^a   Barron, Lynn L ^a   Huh, Yang O ^b   Luthra, Rajyalakshmi ^c   Keating, Michael J ^b   Abruzzo, Lynne V ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Atypical morphologic features; BCL11A; Chronic lymphocytic leukemia small lymphocytic lymphoma; IgV H mutation; T(2; 14)(p16; q32)

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; PEPTIDES AND PROTEINS; PROTEIN BCL 11A; PROTEIN KINASE ZAP 70; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BCL11A PROTEIN, HUMAN; CARRIER PROTEIN; DNA; NUCLEAR PROTEIN; TUMOR MARKER; ZAP70 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BONE MARROW; CANCER MORPHOLOGY; CANCER PATIENT; CANCER SURGERY; CELL DIFFERENTIATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CLINICAL EXAMINATION; CLINICAL FEATURE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; HEPATOSPLENOMEGALY; HISTOPATHOLOGY; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOPHENOTYPING; KARYOTYPE; KARYOTYPING; LYMPHADENOPATHY; LYMPHOCYTOSIS; MALE; PRIORITY JOURNAL; PROLYMPHOCYTE; PROTEIN EXPRESSION; STRUCTURAL CHROMOSOME ABERRATION; CHROMOSOME 14; CHROMOSOME 2; GENE TRANSLOCATION; GENETICS; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 2; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; FLOW CYTOMETRY; GENES, IMMUNOGLOBULIN HEAVY CHAIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; NUCLEAR PROTEINS; TRANSLOCATION, GENETIC; TUMOR MARKERS, BIOLOGICAL; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 65349131189     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AJCPXLY46UPFLISC     Document Type: Article

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