Primary/de novo paroxysmal nocturnal hemoglobinuria in a child from north India: A case report with review of literature

Journal of Pediatric Hematology/Oncology

Volumn 31, Issue 4, 2009, Pages 274-276

  Naseem, Shano ^a   Varma, Neelam ^b   Trehan, Amita ^a  

^a Advanced Pediatric Center   (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Glycosylphosphatidylinositol; Intravascular hemolysis; Paroxysmal nocturnal hemoglobinuria; Pediatric

Indexed keywords

CD59 ANTIGEN; DECAY ACCELERATING FACTOR; GLYCOSYLPHOSPHATIDYLINOSITOL;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW BIOPSY; BONE MARROW DEPRESSION; CASE REPORT; CHILD; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; HUMAN; HUMAN TISSUE; INDIA; MALE; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; SCHOOL CHILD; BLOOD; FLOW CYTOMETRY; HEMOLYSIS; METABOLISM; PATHOLOGY; REVIEW;

CHILD; FLOW CYTOMETRY; GLYCOSYLPHOSPHATIDYLINOSITOLS; HEMOGLOBINURIA, PAROXYSMAL; HEMOLYSIS; HUMANS; INDIA; MALE;

EID: 65349124392     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31819b582b     Document Type: Article

References (18)

1. van den Heuvel-Eibrink MM, Bredius RGM, te Winkel ML, et al. Childhood paroxysmal nocturnal haemoglobinuria, a report of 11 cases in the Netherlands. Br J Haematol. 2005;128: 571-577.
2. Rosse WF. Paroxysmal nocturnal haemoglobinuria: present status and future prospects. West J Med. 1980;132:219-228.
3. Ware RE, Hall SE, Rosse WF. Paroxysmal nocturnal haemoglobinuria with onset in childhood and adolescence. N Engl J Med. 1991;325:991-996.
4. Miller DR, Baehner RL, Diamond LK. Paroxysmal nocturnal haemoglobinuria in childhood and adolescence. Clinical and erythrocyte metabolic studies in 2 cases. Pediatrics. 1967; 39:675-688.
5. Kletzel M, Arnold WC, Berry DH. Paroxysmal nocturnal haemoglobinuria presenting as recurrent uremic haemolytic syndrome. Clin Pediatr. 1987;26:319-320.
6. Wyatt HA, Mowat AP, Layton M. Paroxysmal nocturnal haemoglobinuria and Budd-Chiari syndrome. Arch Dis Child. 1995;72:241-242.
7. Endo M, Betty PG, Vreeke TM, et al. Syngenic bone marrow transplantation without conditioning in a patient with paroxysmal nocturnal haemoglobinuria: in vivo evidence that the mutant cells have a survival advantage. Blood. 1996; 88: 742-750.
8. Graham ML, Rose WF, Halperin EC, et al. Resolution of Budd-Chiari syndrome following bone marrow transplantation for paroxysmal nocturnal haemoglobinuria. Br J Haematol. 1996;92:707-710.
9. Lin HC, Chen RL, Wang PJ. Paroxysmal nocturnal haemo-globinuria presenting as Moyamoya syndrome. Brain dev. 1996;18:157-159.
10. Flotho C, Strahm B, Kontny U, et al. Stem cell transplantation for paroxysmal nocturnal haemoglobinuria in childhood. Br J Haematol. 2002;118:124-127.
11. Rizk S, Ibrahim IY, Mansour IM, et al. Screening for paroxysmal nocturnal haemoglobinuria clone in Egyptian children with aplastic anaemia. J Trop Pediatr. 2002;48: 132-137.
12. Wainwright L, Brodsky RA, Erasmus LK, et al. Paroxysmal nocturnal haemoglobinuria arising from Fanconi anaemia. J Pediatr Hematol Oncol. 2003;25:167-168.
13. Miyata T, Yamada N, Lida Y, et al. Abnormalities of PIG-A transcripts in granulocytes from patients with paroxsymal nocturnal hemoblobinuria. N Engl J Med. 1994;330:249-255.
14. Hillmen P. Implications of recent insights into the pathophy-siology of paroxysmal nocturnal haemoglobinuria. Br J Haematol. 2000;108:470-479.
15. Brubaker LH, Essig LJ, Mengel CE. Neutrophil life span in paroxysmal nocturnal hemoglobinuria. Blood. 1977;50:657-662.
16. Zupanska B, Bogdanik B, Pyl H. A gel microtyping system for diagnosis of paroxysmal nocturnal hemoglobinuria. Immuno-hematology. 2002;18:9-12.
17. Luzzatto L, Notaro R. Paroxysmal nocturnal hemoglobinuria. In: Hoffbrand AV, Catovsky D, Tuddenham EGD, eds. Postgraduate Haematology. 5th ed. Massachusetts: Blackwell Publishing; 2005:169-175.
18. Varma N, Garewal G, Varma S, et al. Flow cytometric detection of PNH defect in Indian patients with aplastic anemia and myelodysplastic syndromes. Am J Hematol. 2000;65:264-265.