Lower Thoracic Spinal Cord Stimulation to Restore Cough in Patients With Spinal Cord Injury: Results of a National Institutes of Health-Sponsored Clinical Trial. Part II: Clinical Outcomes

Archives of Physical Medicine and Rehabilitation

Volumn 90, Issue 5, 2009, Pages 726-732

  DiMarco, Anthony F ^a   Kowalski, Krzysztof E ^a   Geertman, Robert T ^b,c   Hromyak, Dana R ^a   Frost, Fredrick S ^c   Creasey, Graham H ^c   Nemunaitis, Gregory A ^c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c METROHEALTH MEDICAL CENTER   (United States)

Author keywords

Cough; Electric stimulation; Quadriplegia; Rehabilitation; Respiratory muscles; Spinal cord injuries

Indexed keywords

ADULT; ARTICLE; BREATHING DISORDER; BRONCHUS SECRETION; CAREGIVER SUPPORT; CLINICAL ARTICLE; CLINICAL TRIAL; COUGHING; EVALUATION; FEMALE; HUMAN; IMPLANTATION; INCIDENCE; LUNG HEMODYNAMICS; MALE; MORBIDITY; MORTALITY; NATIONAL HEALTH ORGANIZATION; QUALITY OF LIFE; QUESTIONNAIRE; RESPIRATORY CARE; RESPIRATORY TRACT INFECTION; SPINAL CORD INJURY; SPINAL CORD STIMULATION; TREATMENT OUTCOME;

ADULT; COUGH; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; NATIONAL INSTITUTES OF HEALTH (U.S.); PEAK EXPIRATORY FLOW RATE; PROBABILITY; QUADRIPLEGIA; RECOVERY OF FUNCTION; RESPIRATORY FUNCTION TESTS; RESPIRATORY MECHANICS; RESPIRATORY MUSCLES; RESPIRATORY THERAPY; RISK ASSESSMENT; RISK FACTORS; SPINAL CORD INJURIES; THORACIC VERTEBRAE; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 65249172536     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apmr.2008.11.014     Document Type: Article

References (36)

1. DiMarco A.F., Kowalski K.E., Geertman R.T., and Hromyak D.R. Lower thoracic spinal cord stimulation to restore cough in patients with spinal cord injury: results of a National Institutes of Health-sponsored clinical trial. Part I: methodology and effectiveness of expiratory muscle activation. Arch Phys Med Rehabil 90 (2009) 717-725
2. Loudon R.G., and Shaw G.B. Mechanics of cough in normal subjects and in patients with obstructive respiratory disease. Am Rev Respir Dis 96 (1967) 666-677
3. Langlands J. The dynamics of cough in health and in chronic bronchitis. Thorax 22 (1967) 88-96
4. Edström L., and Grimby L. Effect of exercise on the motor unit. Muscle Nerve 9 (1986) 104-126
5. Ferguson A.S., Stone H.E., Roessmann U., Burke M., Tisdale E., and Mortimer J.T. Muscle plasticity: comparison of a 30-Hz burst with 10-Hz continuous stimulation. J Appl Physiol 66 (1989) 1143-1151
6. Kernell D., Eerbeek O., Verhey B.A., and Donselaar Y. Effects of physiological amounts of high- and low-rate chronic stimulation on fast-twitch muscle of the cat hindlimb, I: speed- and force-related properties. J Neurophysiol 58 (1987) 598-613
7. Martin T.P., Stein R.B., Hoeppner P.H., and Reid D.C. Influence of electrical stimulation on the morphological and metabolic properties of paralyzed muscle. J Appl Physiol 72 (1992) 1401-1406
8. Stein R.B., Gordon T., Jefferson J., et al. Optimal stimulation of paralyzed muscle after human spinal cord injury. J Appl Physiol 72 (1992) 1393-1400
9. DiMarco A.F., Romaniuk J.R., and Supinski G.S. Electrical activation of the expiratory muscles to restore cough. Am J Respir Crit Care Med 151 (1995) 1466-1471
10. Krause J.S. Dimensions of subjective well-being after spinal cord injury: an empirical analysis by gender and race/ethnicity. Arch Phys Med Rehabil 79 (1998) 900-909
11. Jain N.B., Sullivan M., Kazis L.E., Tun C.G., and Garshick E. Factors associated with health-related quality of life in chronic spinal cord injury. Am J Phys Med Rehabil 86 (2007) 387-396
12. May L.A., and Warren S. Measuring quality of life of persons with spinal cord injury: external and structural validity. Spinal Cord 40 (2002) 341-350
13. Manns P.J., and Chad K.E. Components of quality of life for persons with a quadriplegic and paraplegic spinal cord injury. Qual Health Res 11 (2001) 795-811
14. Dijkers M.P. Quality of life of individuals with spinal cord injury: a review of conceptualization, measurement, and research findings. J Rehabil Res Dev 42 (2005) 87-110
15. Andresen E.M., Fouts B.S., Romeis J.C., and Brownson C.A. Performance of health-related quality-of-life instruments in a spinal cord injured population. Arch Phys Med Rehabil 80 (1999) 877-884
16. McMichan J.C., Michel L., and Westbrook P.R. Pulmonary dysfunction following traumatic quadriplegia: recognition, prevention and treatment. JAMA 243 (1980) 528-531
17. Carter R.E. Respiratory aspects of spinal cord injury management. Paraplegia 25 (1987) 262-266
18. Jackson A.B., and Groomes T.E. Incidence of respiratory complications following spinal cord injury. Arch Phys Med Rehabil 75 (1994) 270-275
19. Brown R., DiMarco A.F., Hoit J.D., and Garshick E. Respiratory dysfunction and management in spinal cord injury. Respir Care 51 (2006) 853-870
20. Kiwerski J.E. Factors contributing to the increased threat of life following spinal cord injury. Paraplegia 31 (1993) 793-799
21. Hartkopp A., Bronnum-Hansen H., Seidenschnur A.M., and Biering-Sorensen F. Survival and cause of death after traumatic spinal cord injury: a long-term epidemiological survey from Denmark. Spinal Cord 35 (1997) 76-85
22. Frankel H.L., Coll J.R., Charlifue S.W., et al. Long-term survival in spinal cord injury: a fifty year investigation. Spinal Cord 36 (1998) 266-274
23. DeVivo M.J., Krause J.S., and Lammertse D.P. Recent trends in mortality and causes of death among persons with spinal cord injury. Arch Phys Med Rehabil 80 (1999) 1411-1419
24. Smith B.M., Evans C.T., Kurichi J.E., Weaver F.M., Patel N., and Burns S.P. Acute respiratory tract infection visits of veterans with spinal cord injuries and disorders: rates, trends, and risk factors. J Spinal Cord Med 30 (2007) 355-361
25. Cardozo C.P. Respiratory complications of spinal cord injury. J Spinal Cord Med 30 (2007) 307-308
26. Shavelle R.M., DeVivo M.J., Strauss D.J., Paculdo D.R., Lammertse D.P., and Day S.M. Long-term survival of persons ventilator dependent after spinal cord injury. J Spinal Cord Med 29 (2006) 511-519
27. Zimmer M.B., Nantwi K., and Goshgarian H.G. Effect of spinal cord injury on the respiratory system: basic research and current clinical treatment options. J Spinal Cord Med 30 (2007) 319-330
28. Consortium for Spinal Cord Medicine. Clinical Practice Guidelines. Acute Management of Autonomic Dysreflexia: Individuals with Spinal Cord Injury Presenting to Health-Care Facilities. 2nd ed. (2001), Paralyzed Veterans of America, Washington (DC)
29. Woodburne R.T. Essentials of human anatomy (1969), Oxford University Press, New York
30. De Troyer A., Estenne M., and Heilporn A. Mechanism of active expiration in tetraplegic subjects. N Engl J Med 314 (1986) 740-744
31. Estenne M., and De Troyer A. Cough in tetraplegic subjects: an active process. Ann Intern Med 112 (1990) 22-28
32. Sivasothy P., Brown L., Smith I.E., and Shneerson J.M. Effect of manually assisted cough and mechanical insufflation on cough flow of normal subjects, patients with chronic obstructive pulmonary disease (COPD), and patients with respiratory muscle weakness. Thorax 56 (2001) 438-444
33. Braun S.R., Giovannoni R., and O'Connor M. Improving the cough in patients with spinal cord injury. Am J Phys Med 63 (1984) 1-10
34. Chatwin M., Ross E., Hart N., Nickol A.H., Polkey M.I., and Simonds A.K. Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness. Eur Respir J 21 (2003) 502-508
35. Bach J.R. Mechanical insufflation-exsufflation: comparison of peak expiratory flows with manually assisted and unassisted coughing techniques. Chest 104 (1993) 1553-1562
36. Homnick D.N. Mechanical insufflation-exsufflation for airway mucus clearance. Respir Care 52 (2007) 1296-1307