Do estrogens impact adolescent idiopathic scoliosis?

Trends in Endocrinology and Metabolism

Volumn 20, Issue 4, 2009, Pages 147-152

  Leboeuf, Dominique ^a   Letellier, Kareen ^a   Alos, Nathalie ^a,b   Edery, Patrick ^c,d   Moldovan, Florina ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ LYON 1   (France)

^d HOSPICES CIVILS DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; MELATONIN; PHYTOESTROGEN;

ARTICLE; BIOMECHANICS; BONE GROWTH; BONE REMODELING; DISEASE ASSOCIATION; DISEASE COURSE; ESTROGEN ACTIVITY; IDIOPATHIC SCOLIOSIS; OSTEOPENIA; PATHOGENESIS; PRIORITY JOURNAL; SPINE MALFORMATION;

ADOLESCENT; BIOMECHANICS; BONE REMODELING; ESTROGENS; HUMANS; RECEPTORS, ESTROGEN; SCOLIOSIS;

EID: 65249163455     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2008.12.004     Document Type: Article

References (77)

1. Weinstein S.L., et al. Adolescent idiopathic scoliosis. Lancet 371 (2008) 1527-1537
2. Sarwark J., and Aubin C.E. Growth considerations of the immature spine. J. Bone Joint Surg. Am. 89 Suppl 1 (2007) 8-13
3. Sanders J.O., et al. Maturity assessment and curve progression in girls with idiopathic scoliosis. J. Bone Joint Surg. Am. 89 (2007) 64-73
4. Eastell R. Role of oestrogen in the regulation of bone turnover at the menarche. J. Endocrinol. 185 (2005) 223-234
5. Parent S., et al. Adolescent idiopathic scoliosis: etiology, anatomy, natural history, and bracing. Instr. Course Lect. 54 (2005) 529-536
6. Heary R.F., and Madhavan K. Genetics of scoliosis. Neurosurgery 63 (2008) 222-227
7. Miller N.H. Genetics of familial idiopathic scoliosis. Clin. Orthop. Relat. Res. (2002) 60-64
8. Salehi L.B., et al. Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11. Hum. Genet. 111 (2002) 401-404
9. Gao X., et al. CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis. Am. J. Hum. Genet. 80 (2007) 957-965
10. Wise C.A., et al. Localization of susceptibility to familial idiopathic scoliosis. Spine 25 (2000) 2372-2380
11. Ocaka L., et al. Assignment of two loci for autosomal dominant adolescent idiopathic scoliosis to chromosomes. J. Med. Genet. 45 (2008) 87-92
12. Akhtar S., et al. Ultrastructural localization and distribution of proteoglycan in normal and scoliotic lumbar disc. Spine 30 (2005) 1303-1309
13. Antoniou J., et al. Elevated synthetic activity in the convex side of scoliotic intervertebral discs and endplates compared with normal tissues. Spine 26 (2001) E198-E206
14. Pyeritz R.E., and McKusick V.A. The Marfan syndrome: diagnosis and management. N. Engl. J. Med. 300 (1979) 772-777
15. Lupparelli S., et al. Biomechanical factors affecting progression of structural scoliotic curves of the spine. Stud. Health Technol. Inform. 91 (2002) 81-85
16. Spencer G.S., and Zorab P.A. Spinal muscle in scoliosis. Part 1. Histology and histochemistry. J. Neurol. Sci 30 (1976) 137-142
17. 2+-ATPases: new markers of cell differentiation as illustrated in idiopathic scoliosis. Platelets 17 (2006) 421-433
18. Lowe T., et al. Platelet calmodulin levels in adolescent idiopathic scoliosis: do the levels correlate with curve progression and severity?. Spine 27 (2002) 768-775
19. Iwamuro S., et al. Teratogenic and anti-metamorphic effects of bisphenol A on embryonic and larval Xenopus laevis. Gen. Comp. Endocrinol. 133 (2003) 189-198
20. Boudreau M., et al. Utility of morphological abnormalities during early-life development of the estuarine mummichog, Fundulus heteroclitus, as an indicator of estrogenic and antiestrogenic endocrine disruption. Environ. Toxicol. Chem. 23 (2004) 415-425
21. Kulis A., et al. Concentration of estradiol in girls with idiophatic scoliosis. Ortop. Traumatol. Rehabil. 8 (2006) 455-459
22. Raczkowski J.W. The concentrations of testosterone and estradiol in girls with adolescent idiopathic scoliosis. Neuroendocrinol. Lett. 28 (2007) 302-304
23. Grivas T.B., et al. Association between adolescent idiopathic scoliosis prevalence and age at menarche in different geographic latitudes. Scoliosis 1 (2006) 9
24. Warren M.P., et al. Scoliosis and fractures in young ballet dancers. Relation to delayed menarche and secondary amenorrhea. N. Engl. J. Med 314 (1986) 1348-1353
25. Letellier K., et al. Estrogen cross-talk with the melatonin signaling pathway in human osteoblasts derived from adolescent idiopathic scoliosis patients. J. Pineal Res. 45 (2008) 383-393
26. Ascenzi P., et al. Structure-function relationship of estrogen receptor alpha and beta: impact on human health. Mol. Aspects Med. 27 (2006) 299-402
27. Zallone A. Direct and indirect estrogen actions on osteoblasts and osteoclasts. Ann. N. Y. Acad. Sci. 1068 (2006) 173-179
28. Wu J., et al. Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis. Spine 31 (2006) 1131-1136
29. Tang N.L., et al. A relook into the association of the estrogen receptor α gene (PvuII, XbaI) and adolescent idiopathic scoliosis: a study of 540 Chinese cases. Spine 31 (2006) 2463-2468
30. Inoue M., et al. Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis. Spine 27 (2002) 2357-2362
31. Cheng J.C., et al. Persistent osteopenia in adolescent idiopathic scoliosis. A longitudinal follow up study. Spine 24 (1999) 1218-1222
32. Grumbach M.M., and Auchus R.J. Estrogen: consequences and implications of human mutations in synthesis and action. J. Clin. Endocrinol. Metab. 84 (1999) 4677-4694
33. Bilezikian J.P., et al. Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N. Engl. J. Med. 339 (1998) 599-603
34. Riggs B.L., et al. Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev. 23 (2002) 279-302
35. Slemenda C.W., et al. Influences on skeletal mineralization in children and adolescents: evidence for varying effects of sexual maturation and physical activity. J. Pediatr. 125 (1994) 201-207
36. Manolagas S.C., and Jilka R.L. Cytokines, hematopoiesis, osteoclastogenesis, and estrogens. Calcif. Tissue Int. 50 (1992) 199-202
37. Cheng J.C., et al. Persistent osteopenia in adolescent idiopathic scoliosis - longitudinal monitoring of bone mineral density until skeletal maturity. Stud. Health Technol. Inform. 123 (2006) 47-51
38. Yoshihara H., et al. A histomorphologic study of scoliosis in pinealectomized chickens. Spine 30 (2005) 2244-2251
39. Goto M., et al. Buckling and bone modeling as factors in the development of idiopathic scoliosis. Spine 28 (2003) 364-371
40. Aulisa L., et al. Association between IL-6 and MMP-3 gene polymorphisms and adolescent idiopathic scoliosis: a case-control study. Spine 32 (2007) 2700-2702
41. Perry M.J., et al. Impaired growth plate function in bmp-6 null mice. Bone 42 (2008) 216-225
42. Nilsson O., et al. Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages. J. Endocrinol. 177 (2003) 319-326
43. Weise M., et al. Effects of estrogen on growth plate senescence and epiphyseal fusion. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 6871-6876
44. Drop S.L., et al. Sex steroid treatment of constitutionally tall stature. Endocr. Rev. 19 (1998) 540-558
45. Ylikoski M. Height of girls with adolescent idiopathic scoliosis. Eur. Spine J. 12 (2003) 288-291
46. Docquier P.L., et al. Orthopaedic concerns in children with growth hormone therapy. Acta Orthop. Belg. 70 (2004) 299-305
47. Dymling J.F., and Willner S. Progression of a structural scoliosis during treatment with growth hormone. A case report. Acta Orthop. Scand 49 (1978) 264-268
48. Vidil A., et al. Evolution of scoliosis in six children treated with growth hormone. J. Pediatr. Orthop. B. 10 (2001) 197-200
49. Nilsson O., et al. Endocrine regulation of the growth plate. Horm. Res. 64 (2005) 157-165
50. Cheng J.C., et al. Generalized low areal and volumetric bone mineral density in adolescent idiopathic scoliosis. J. Bone Miner. Res. 15 (2000) 1587-1595
51. Whedon M., and Damianos F.L. Nursing care issues in autologous bone marrow transplantation. Oncology 7 (1993) 78-88
52. Lanyon L.E. Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone. Bone 18 (1996) 37S-43S
53. Willy C., et al. Richard von Volkmann: surgeon and Renaissance man. Clin. Orthop. Relat. Res. 466 (2008) 500-506
54. Zaman G., et al. Osteocytes use estrogen receptor alpha to respond to strain but their ERα content is regulated by estrogen. J. Bone Miner. Res. 21 (2006) 1297-1306
55. Damien E., et al. The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain. J. Bone Miner. Res. 13 (1998) 1275-1282
56. Armstrong V.J., et al. Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha. J. Biol. Chem. 282 (2007) 20715-20727
57. Boyden L.M., et al. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346 (2002) 1513-1521
58. Gong Y., et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107 (2001) 513-523
59. Machida M., et al. Pathologic mechanism of experimental scoliosis in pinealectomized chickens. Spine 26 (2001) E385-E391
60. Azeddine B., et al. Molecular determinants of melatonin signaling dysfunction in adolescent idiopathic scoliosis. Clin. Orthop. Relat. Res. 462 (2007) 45-52
61. Soares Jr. J.M., et al. Functional melatonin receptors in rat ovaries at various stages of the estrous cycle. J. Pharmacol. Exp. Ther. 306 (2003) 694-702
62. Buhimschi I.A., et al. Pregnancy and estradiol decrease GTPase activity in the guinea pig uterine artery. Am. J. Physiol. Heart Circ. Physiol. 281 (2001) H2168-H2175
63. Cos S., et al. Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells. Cancer Res. 58 (1998) 4383-4390
64. Cos S., and Sanchez-Barcelo E.J. Melatonin, experimental basis for a possible application in breast cancer prevention and treatment. Histol. Histopathol. 15 (2000) 637-647
65. Ram P.T., et al. Differential responsiveness of MCF-7 human breast cancer cell line stocks to the pineal hormone, melatonin. J. Pineal Res. 28 (2000) 210-218
66. Wilson S.T., et al. Melatonin augments the sensitivity of MCF-7 human breast cancer cells to tamoxifen in vitro. J. Clin. Endocrinol. Metab. 75 (1992) 669-670
67. Watson C.S., et al. Nongenomic actions of estradiol compared with estrone and estriol in pituitary tumor cell signaling and proliferation. FASEB J. 22 (2008) 3328-3336
68. Godson C., and Reppert S.M. The Mel1a melatonin receptor is coupled to parallel signal transduction pathways. Endocrinology 138 (1997) 397-404
69. del Rio B., et al. Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin. J. Biol. Chem. 279 (2004) 38294-38302
70. Moreau A., et al. Melatonin signaling dysfunction in adolescent idiopathic scoliosis. Spine 29 (2004) 1772-1781
71. Lee W.T., et al. Association of osteopenia with curve severity in adolescent idiopathic scoliosis: a study of 919 girls. Osteoporos. Int. 16 (2005) 1924-1932
72. Lee W.T., et al. Generalized low bone mass of girls with adolescent idiopathic scoliosis is related to inadequate calcium intake and weight bearing physical activity in peripubertal period. Osteoporos. Int. 16 (2005) 1024-1035
73. Cos P., et al. Phytoestrogens: recent developments. Planta Med. 69 (2003) 589-599
74. Rickard D.J., et al. Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. J. Cell. Biochem. 89 (2003) 633-646
75. Wang H., et al. Variation in commercial rodent diets induces disparate molecular and physiological changes in the mouse uterus. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 9960-9965
76. De Wilde A., et al. A low dose of daidzein acts as an ERβ-selective agonist in trabecular osteoblasts of young female piglets. J. Cell. Physiol. 200 (2004) 253-262
77. Papaioannou S., et al. G-protein signalling pathways and oestrogen: a role of balanced maintenance in osteoblasts. Biochim. Biophys. Acta 1449 (1999) 284-292