Structural and functional studies of QdtC: An N-acetyltransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-R-D-glucose

Biochemistry

Volumn 48, Issue 12, 2009, Pages 2699-2709

  Thoden, James B ^a   Cook, Paul D ^a   Schäffer, Christina ^b   Messner, Paul ^b   Holden, Hazel M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDO; ACETYL-COA; ACTIVE SITES; AMINO ACID RESIDUES; AMINO GROUPS; BIOSYNTHETIC PATHWAYS; CATALYTIC BASE; CATALYTIC MECHANISMS; D GALACTOSE; D GLUCOSE; GLYCANS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MUTANT PROTEINS; N-ACETYLTRANSFERASE; PROTON ACCEPTORS; S LAYERS; SUBUNIT INTERFACES; TERNARY COMPLEXES; TRIMERIC ENZYMES; WILD-TYPE ENZYMES;

AMINATION; AMINES; AMINO ACIDS; BACTERIA; BACTERIOLOGY; BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; BIOSYNTHESIS; GLUCOSE; ORGANIC ACIDS; SUGAR (SUCROSE); SULFUR;

ENZYMES;

3 ACETAMIDO 3,6 DIDEOXY ALPHA DELTA GLUCOSE; ACETYL COENZYME A; ACYLTRANSFERASE; ACYLTRANSFERASE QDTC; AMINO ACID; ASPARAGINE; ASPARTIC ACID; BETA HELIX MOTIF; COENZYME A; GALACTOSE; GLUCOSE; GLUCOSE DERIVATIVE; GLUTAMIC ACID; HELIX LOOP HELIX PROTEIN; HEXOSE; HISTIDINE; LIGAND; MUTANT PROTEIN; SUGAR; TERNARY COMPLEX FACTOR; THYMIDINE DIPHOSPHATE; THYMIDINE DIPHOSPHATE 3 ACETAMIDO 3,6 DIDEOXY ALPHA DEXTRO GLUCOSE; THYMIDINE DIPHOSPHATE 3 AMINO 3,6 DIDEOXY ALPHA DEXTRO GALACTOSE; UNCLASSIFIED DRUG;

ACETYLATION; AMINO ACID SUBSTITUTION; ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; BACTERIAL METABOLISM; BINDING KINETICS; BINDING SITE; CARBOHYDRATE SYNTHESIS; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CHEMISTRY; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; WILD TYPE;

ACETYLTRANSFERASES; CATALYSIS; DEOXY SUGARS; MODELS, MOLECULAR; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THYMINE NUCLEOTIDES;

NEGIBACTERIA;

EID: 65249154793     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802313n     Document Type: Article

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