Molecular basis for dimer formation of TRβ variant D355R

Proteins: Structure, Function and Bioinformatics

Volumn 75, Issue 1, 2009, Pages 111-117

  Jouravel, Natalia ^a,b,c   Sablin, Elena ^a   Togashi, Marie ^b   Baxter, John D ^b   Webb, Paul ^b   Fletterick, Robert J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

Author keywords

Crystal structure; Homo dimer; Ligand binding domain; Protein purification; Thyroid hormone receptor

Indexed keywords

THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR ALPHA 1; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA 1; THYROID HORMONE RECEPTOR BETA 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN VARIANT;

CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MUTANT PROTEINS; POINT MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; RECEPTORS, THYROID HORMONE;

EID: 65249154227     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22225     Document Type: Article

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