Lipid emulsion may augment early blood pressure recovery in a rabbit model of atenolol toxicity

Journal of Medical Toxicology

Volumn 5, Issue 1, 2009, Pages 50-51

  Cave, Grant ^a,b   Harvey, Martyn ^c  

^a HUTT HOSPITAL   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c c/o Emergency Department ^*  (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; LIPID EMULSION; ANTIDOTE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL HUSBANDRY; ANIMAL MODEL; ARTIFICIAL VENTILATION; BLOOD PRESSURE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG INTOXICATION; FEMALE; HEMODYNAMICS; HUMAN; HYPOTENSION; LETTER; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RABBIT; SHOCK; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; PATHOPHYSIOLOGY; TIME;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ANTIDOTES; ATENOLOL; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FAT EMULSIONS, INTRAVENOUS; HYPOTENSION; RABBITS; TIME FACTORS;

EID: 65249149773     PISSN: 15569039     EISSN: 19376995     Source Type: Journal    
DOI: 10.1007/BF03160983     Document Type: Letter

References (5)

1. Turner-Lawrence D, Kerns W. Intravenous fat emulsion: a potential novel antidote. J Med Toxicol 2008;4:109-114.
2. Harvey M, Cave G. Intralipid outperforms sodium bicarbonate in a rabbit model of clomipramine toxicity. Ann Emerg Med 2007;49:178-185.
3. Harvey M, Cave G. Intralipid infusion ameliorates propranolol induced hypotension in rabbits. J Med Toxicol 2008;4:71-76.
4. Dreisbach A, Greif R, Lorenzo B, et al. Lipophilic Beta-Blockers Inhibit Rat Skeletal Muscle Mitochondrial Respiration. Pharmacology 1993;47:295-299.
5. Sasao J, Tarver S, Kindsher J, et al. In rabbits, landiolol, a new ultra short acting beta blocker, exerts a more potent negative chronotropic effect and less effect on blood pressure than esmolol. Can J Anaesth 2001; 41:985-989.