A Randomized Controlled Trial of Sertraline for the Treatment of Depression in Persons With Traumatic Brain Injury

Archives of Physical Medicine and Rehabilitation

Volumn 90, Issue 5, 2009, Pages 733-740

  Ashman, Teresa A ^a   Cantor, Joshua B ^a   Gordon, Wayne A ^a   Spielman, Lisa ^c   Flanagan, Steve ^b   Ginsberg, Annika ^b   Engmann, Clara ^a   Egan, Matthew ^a   Ambrose, Felicia ^a   Greenwald, Brian ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Congers ^*  (United States)

Author keywords

Anxiety; Brain injuries; Depression; Minority groups; Randomized controlled trials publication type ; Rehabilitation; Sertraline

Indexed keywords

PLACEBO; SERTRALINE;

ADULT; ANALYSIS OF VARIANCE; ANXIETY; ARTICLE; BECK ANXIETY INVENTORY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HAMILTON SCALE; HUMAN; INCOME; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MOOD; OUTCOME ASSESSMENT; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ADULT; ANTIDEPRESSIVE AGENTS; BRAIN INJURIES; DEPRESSIVE DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PROBABILITY; PSYCHIATRIC STATUS RATING SCALES; QUALITY OF LIFE; REFERENCE VALUES; RISK ASSESSMENT; SERTRALINE; TREATMENT OUTCOME;

EID: 65249147167     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apmr.2008.11.005     Document Type: Article

References (88)

1. Ashman T.A., Spielman L.A., Hibbard M.R., Silver J.M., Chandna T., and Gordon W.A. Psychiatric challenges in the first 6 years after traumatic brain injury: cross-sequential analyses of Axis I disorders. Arch Phys Med Rehabil 85 (2004) S36-S42
2. Kim E., Lauterbach E.C., Reeve A., et al. Neuropsychiatric complications of traumatic brain injury: a critical review of the literature (a report by the ANPA committee on research). J Neuropsychiatry Clin Neurosci 19 (2007) 106-127
3. Rapoport M.J., McCullagh S., Shammi P., and Feinstein A. Cognitive impairment associated with major depression following mild and moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci 17 (2005) 61-65
4. Hibbard M.R., Uysal S., Kepler K., Bogdany J., and Silver J. Axis I psychopathology in individuals with traumatic brain injury. J Head Trauma Rehabil 13 (1998) 24-39
5. Jorge R.E., Robinson R.G., Starkstein S.E., and Arndt S.V. Depression and anxiety following traumatic brain injury. J Neuropsychiatry Clin Neurosci 5 (1993) 369-374
6. Jorge R.E., Robinson R.G., Arndt S.V., Starkstein S.E., Forrester A.W., and Geisler F. Depression following traumatic brain injury: a 1 year longitudinal study. J Affect Disord 27 (1993) 233-243
7. Jorge R.E., Robinson R.G., and Arndt S. Are there symptoms that are specific for depressed mood in patients with traumatic brain injury?. J Nerv Ment Dis 181 (1993) 91-99
8. Jorge R.E., Robinson R.G., Moser D., Tateno A., Crespo-Facorro B., and Arndt S. Major depression following traumatic brain injury. Arch Gen Psychiatry 61 (2004) 42-50
9. Fann J.R., Katon W.J., Uomoto J.M., and Esselman P.C. Psychiatric disorders and functional disability in outpatients with traumatic brain injuries. Am J Psychiatry 152 (1995) 1493-1499
10. Bowen A., Neumann V., Conner M., Tennant A., and Chamberlain M.A. Mood disorders following traumatic brain injury: identifying the extent of the problem and the people at risk. Brain Inj 12 (1998) 177-190
11. Holsinger T., Steffens D.C., Phillips C., et al. Head injury in early adulthood and the lifetime risk of depression. Arch Gen Psychiatry 59 (2002) 17-22
12. Kreutzer J.S., Seel R.T., and Gourley E. The prevalence and symptom rates of depression after traumatic brain injury: a comprehensive examination. Brain Inj 15 (2001) 563-576
13. Glenn M.B., O'Neil-Pirozzi T., Goldstein R., Burke D., and Jacob L. Depression amongst outpatients with traumatic brain injury. Brain Inj 15 (2001) 811-818
14. Seel R.T., Kreutzer J.S., Rosenthal M., Hammond F.M., Corrigan J.D., and Black K. Depression after traumatic brain injury: a national institute on disability and rehabilitation research model systems multicenter investigation. Arch Phys Med Rehabil 84 (2003) 177-184
15. Koponen S., Taiminen T., Portin R., et al. Axis I and II psychiatric disorders after traumatic brain injury: a 30-year follow-up study. Am J Psychiatry 159 (2002) 1315-1321
16. Kessler R.C., Berglund P., Demler O., Jin R., Merikangas K.R., and Walters E.E. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication. Arch Gen Psychiatry 62 (2005) 593-602
17. Bourdon K.H., Rae D.S., Locke B.Z., Narrow W.E., and Regier D.A. Estimating the prevalence of mental disorders in U.S. adults from the epidemiologic catchment area survey. Public Health Rep 107 (1992) 663-668
18. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. (1994), APA, Washington, DC
19. Chamelian L., and Feinstein A. The effect of major depression on subjective and objective cognitive deficits in mild to moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci 18 (2006) 33-38
20. Rapoport M.J., McCullagh S., Streiner D., and Feinstein A. The clinical significance of major depression following mild traumatic brain injury. Psychosomatics 44 (2003) 31-37
21. Levin H.S., McCauley S.R., Josic C.P., et al. Predicting depression following mild traumatic brain injury. Arch Gen Psychiatry 62 (2005) 523-528
22. Hibbard M.R., Ashman T.A., Spielman L.A., Chun D., Charatz H.J., and Melvin S. Relationship between depression and psychosocial functioning after traumatic brain injury. Arch Phys Med Rehabil 85 (2004) S43-S53
23. Fedoroff J.P., Starkstein S.E., Forrester A.W., et al. Depression in patients with acute traumatic brain injury. Am J Psychiatry 149 (1992) 918-923
24. Deb S., Lyons I., Koutzoukis C., Ali I., and McCarthy G. Rate of psychiatric illness 1 year after traumatic brain injury. Am J Psychiatry 156 (1999) 374-378
25. Bryant R.A., Marosszeky J.E., Crooks J., Baguley I., and Gurka J. Coping style and post-traumatic stress disorder following severe traumatic brain injury. Brain Inj 14 (2000) 175-180
26. Jorge R.E., Robinson R.G., Starkstein S.E., and Arndt S.V. Influence of major depression on 1-year outcome in patients with traumatic brain injury. J Neurosurg 81 (1994) 726-733
27. van Reekum R., Bolago I., Finlayson M.A., Garner S., and Links P.S. Psychiatric disorders after traumatic brain injury. Brain Inj 10 (1996) 319-327
28. Malec J.F., Testa J.A., Rush B.K., Brown A.W., and Moessner A.M. Self-assessment of impairment, impaired self-awareness, and depression after traumatic brain injury. J Head Trauma Rehabil 22 (2007) 156-166
29. Rosenthal M., Christensen B.K., and Ross T.P. Depression following traumatic brain injury. Arch Phys Med Rehabil 79 (1998) 90-103
30. National Institute of Health. Rehabilitation of persons with traumatic brain injury. NIH Consensus Statement 16 (1998) Oct 26-28
31. Tenovuo O. Pharmacological enhancement of cognitive and behavioral deficits after traumatic brain injury. Curr Opin Neurol 19 (2006) 528-533
32. O'Shanick G.J. Update on antidepressants. J Head Trauma Rehabil 21 (2006) 282-284
33. Zafonte R.D., Cullen N., and Lexell J. Serotonin agents in the treatment of acquired brain injury. J Head Trauma Rehabil 17 (2002) 322-334
34. Alderfer B.S., Arciniegas D.B., and Silver J.M. Treatment of depression following traumatic brain injury. J Head Trauma Rehabil 20 (2005) 544-562
35. Jorge R.E., and Starkstein S.E. Pathophysiologic aspects of major depression following traumatic brain injury. J Head Trauma Rehabil 20 (2005) 475-487
36. Glenn M.B., and Wroblewski B. Twenty years of pharmacology. J Head Trauma Rehabil 20 (2005) 51-61
37. Silver J.M., Sandberg D.P., and Hales R.E. New approaches in the pharmacotherapy of posttraumatic stress disorder. J Clin Psychiatry 51 Suppl (1990) 33-38
38. Turner-Stokes L., MacWalter R., Guideline Development Group of the British Society of Rehabilitation Medicine, British Geriatrics Society, and Royal College of Physicians London. Use of antidepressant medication following acquired brain injury: concise guidance. Clin Med 5 (2005) 268-274
39. Warden D.L., Gordon B., et al., Neurobehavioral Guidelines Working Group. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma 23 (2006) 1468-1501
40. Almeida O.P., Waterreus A., and Hankey G.J. Preventing depression after stroke: results from a randomized placebo-controlled trial. J Clin Psychiatry 67 (2006) 1104-1109
41. Spalletta G., Ripa A., Bria P., Caltagirone C., and Robinson R.G. Response of emotional unawareness after stroke to antidepressant treatment. Am J Geriatr Psychiatry 14 (2006) 220-227
42. Murray V., von Arbin M., Bartfai A., et al. Double-blind comparison of sertraline and placebo in stroke patients with minor depression and less severe major depression. J Clin Psychiatry 66 (2005) 708-716
43. Spalletta G., and Caltagirone C. Sertraline treatment of post-stroke major depression: an open study in patients with moderate to severe symptoms. Funct Neurol 18 (2003) 227-232
44. Rasmussen A., Lunde M., Poulsen D.L., Sorensen K., Qvitzau S., and Bech P. A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients. Psychosomatics 44 (2003) 216-221
45. Spalletta G., Guida G., and Caltagirone C. Is left stroke a risk-factor for selective serotonin reuptake inhibitor antidepressant treatment resistance?. J Neurol 250 (2003) 449-455
46. Turner-Stokes L., Hassan N., Pierce K., and Clegg F. Managing depression in brain injury rehabilitation: the use of an integrated care pathway and preliminary report of response to sertraline. Clin Rehabil 16 (2002) 261-268
47. Turner-Stokes L., and Hassan N. Depression after stroke: a review of the evidence base to inform the development of an integrated care pathway. Part 2: treatment alternatives. Clin Rehabil 16 (2002) 248-260
48. Goodnick P.J., and Hernandez M. Treatment of depression in comorbid medical illness. Expert Opin Pharmacother 1 (2000) 1367-1384
49. Burns A., Russell E., Stratton-Powell H., Tyrell P., O'Neill P., and Baldwin R. Sertraline in stroke-associated lability of mood. Int J Geriatr Psychiatry 14 (1999) 681-685
50. Piccinelli M., Patterson M., Braithwaite I., Boot D., and Wilkinson G. Anxiety and depression disorders 5 years after severe injuries: a prospective follow-up study. J Psychosom Res 46 (1999) 455-464
51. Kamijima K., and Aoki M. Effectiveness of paroxetine in the treatment of obsessive-compulsive disorders. Expert Rev Neurother 6 (2006) 945-956
52. Davidson J.R. Pharmacologic treatment of acute and chronic stress following trauma: 2006. J Clin Psychiatry 67 Suppl 2 (2006) 34-39
53. Cipriani A., Brambilla P., Furukawa T., et al. Fluoxetine versus other types of pharmacotherapy for depression. Cochrane Database Syst Rev 4 (2005) CD004185
54. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 23 (1960) 56-62
55. Beck A.T., Steer R., and Brown G. Beck Depression Inventory-II (1996), Psychological Corp, San Antonio
56. Andrews F.M., and Withey S.B. Social indicators of well-being: Americans' perceptions of life quality (1976), Plenum Pr, New York
57. Beck A.T. Beck Anxiety Inventory (1993), Psychological Corp, San Antonio
58. Fann J.R., Uomoto J.M., and Katon W.J. Sertaline in the treatment of major depression following mild traumatic brain injury. J Neuropsychiatry Clin Neurosci 12 (2000) 226-232
59. First M., Spitzer R., Gibbon M., and Williams J. User's guide for the structured clinical interview for DSM-IV Axis I Disorders - SCID (1997), American Psychiatric Pr, Washington, DC
60. Spitzer R.L., Williams J.B., Gibbon M., and First M.B. The structured clinical interview for DSM-III-R (SCID). I: history, rationale, and description. Arch Gen Psychiatry 49 (1992) 624-629
61. Bowman E.S., and Coons P.M. The differential diagnosis of epilepsy, pseudoseizures, dissociative identity disorder, and dissociative disorder not otherwise specified. Bull Menninger Clin 64 (2000) 164-180
62. Segal D.L., Hersen M., and Van Hasselt V.B. Reliability of the structured clinical interview for DSM-III-R: an evaluative review. Compr Psychiatry 35 (1994) 316-327
63. Fach M., Bischof G., Schmidt C., and Rumpf H.J. Prevalence of dependence on prescription drugs and associated mental disorders in a representative sample of general hospital patients. Gen Hosp Psychiatry 29 (2007) 257-263
64. Jones J.E., Hermann B.P., Woodard J.L., et al. Screening for major depression in epilepsy with common self-report depression inventories. Epilepsia 46 (2005) 731-735
65. Booth B.M., Kirchner J.E., Hamilton G., Harrell R., and Smith G.R. Diagnosing depression in the medically ill: validity of a lay-administered structured diagnostic interview. J Psychiatr Res 32 (1998) 353-360
66. Williams J.B. A structured interview guide for the Hamilton Depression Rating Scale. Arch Gen Psychiatry 45 (1988) 742-747
67. Faries D., Herrera J., Rayamajhi J., DeBrota D., Demitrack M., and Potter W.Z. The responsiveness of the Hamilton Depression Rating Scale. J Psychiatr Res 34 (2000) 3-10
68. Williams J.B., Gibbon M., First M.B., et al. The structured clinical interview for DSM-III-R (SCID). II. Multisite test-retest reliability. Arch Gen Psychiatry 49 (1992) 630-636
69. Maier W. The Hamilton Depression Scale and its alternatives: a comparison of their reliability and validity. Psychopharmacol Ser 9 (1990) 64-71
70. Maier W., Heuser I., Philipp M., Frommberger U., and Demuth W. Improving depression severity assessment-II. Content, concurrent and external validity of three observer depression scales. J Psychiatr Res 22 (1988) 13-19
71. Maier W., Philipp M., Heuser I., Schlegel S., Buller R., and Wetzel H. Improving depression severity assessment-I. Reliability, internal validity and sensitivity to change of three observer depression scales. J Psychiatr Res 22 (1988) 3-12
72. Rehm L.P., and O'Hara M.W. Item characteristics of the Hamilton Rating Scale for Depression. J Psychiatr Res 19 (1985) 31-41
73. Bech P., Allerup P., Reisby N., and Gram L.F. Assessment of symptom change from improvement curves on the Hamilton Depression Scale in trials with antidepressants. Psychopharmacology (Berl) 84 (1984) 276-281
74. Gibbons R.D., Clark D.C., and Kupfer D.J. Exactly what does the Hamilton Depression Rating Scale measure?. J Psychiatr Res 27 (1993) 259-273
75. Beck A.T., Epstein N., Brown G., and Steer R.A. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 56 (1988) 893-897
76. Trahan D.E., Ross C.E., and Trahan S.L. Relationships among postconcussional-type symptoms, depression, and anxiety in neurologically normal young adults and victims of mild brain injury. Arch Clin Neuropsychol 16 (2001) 435-445
77. Fleming J.M., Strong J., and Ashton R. Cluster analysis of self-awareness levels in adults with traumatic brain injury and relationship to outcome. J Head Trauma Rehabil 13 (1998) 39-51
78. Wallace C.A., and Bogner J. Awareness of deficits: emotional implications for persons with brain injury and their significant others. Brain Inj 14 (2000) 549-562
79. Dijkers M., Layman D., Ashman T., and Brown M. Self-report of quality of life by persons with traumatic brain injury: a reliability study. Qual Life Res 11 (2002) 672
80. Diggle P.J., Heagerty P., Liang K.Y., and Zeger S.L. Analysis of longitudinal data. 2nd ed. (2002), Oxford Univ Pr, Oxford
81. Robins L.N., and Regier D.A. Psychiatric disorders in America: the epidemiologic catchment area study (1991), Free Pr, New York
82. Demyttenaere K., Bruffaerts R., Posada-Villa J., et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization world mental health surveys. JAMA 291 (2004) 2581-2590
83. Kessler R.C., Berglund P., Demler O., et al. The epidemiology of major depressive disorder: results from the national comorbidity survey replication (NCS-R). JAMA 289 (2003) 3095-3105
84. Greenberg P.E., Kessler R.C., Birnbaum H.G., et al. The economic burden of depression in the United States: how did it change between 1990 and 2000?. J Clin Psychiatry 64 (2003) 1465-1475
85. Blazer D.G., Kessler R.C., McGonagle K.A., and Swartz M.S. The prevalence and distribution of major depression in a national community sample: the national comorbidity survey. Am J Psychiatry 151 (1994) 979-986
86. US Department of Health and Human Services. Mental health: culture, race, and ethnicity: a supplement to mental health: a report of the surgeon general-executive summary (2001), US Dept of Health and Human Services, Public Health Service, Office of the Surgeon General, Rockville
87. Givens J.L., Houston T.K., Van Voorhees B.W., Ford D.E., and Cooper L.A. Ethnicity and preferences for depression treatment. Gen Hosp Psychiatry 29 (2007) 182-191
88. Wang J., White-Means S.I., Hufstader M.A., and Walker G.D. The economic implications of the racial and ethnic disparities in the use of selective serotonin reuptake inhibitors. Curr Med Res Opin 23 (2007) 853-863