Prostate-specific antigen is a "chymotrypsin-like" serine protease with unique P1 substrate specificity

Biochemistry

Volumn 48, Issue 15, 2009, Pages 3490-3496

  LeBeau, Aaron M ^a,b   Singh, Pratap ^a,c   Isaacs, John T ^a,c   Denmeade, Samuel R ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROPHOBIC RESIDUES; IMAGING AGENTS; POTENT INHIBITORS; PROSTATE CANCERS; PROSTATE-SPECIFIC ANTIGENS; SERINE PROTEASE; STRUCTURAL EVIDENCES; STRUCTURAL MOTIFS; SUBSTRATE SPECIFICITIES;

ALDEHYDES; AMINES; AMINO ACIDS; ANTIGENS; CRYSTAL STRUCTURE; HYDROPHOBICITY;

PEELING;

CHYMOTRYPSIN; GLUTAMINE DERIVATIVE; PEPTIDE DERIVATIVE; PROSTATE SPECIFIC ANTIGEN;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROPHOBICITY; PRIORITY JOURNAL;

ALDEHYDES; AMINO ACID MOTIFS; ANIMALS; CATTLE; CHYMOTRYPSIN; ENZYME INHIBITORS; GLUTAMINE; HUMANS; PEPTIDES; PROSTATE-SPECIFIC ANTIGEN; STRUCTURAL HOMOLOGY, PROTEIN; SUBSTRATE SPECIFICITY;

EID: 65249109808     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9001858     Document Type: Article

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