Pitfalls and success of experimental design in the development of a mixed MEKC method for the analysis of budesonide and its impurities

Electrophoresis

Volumn 30, Issue 4, 2009, Pages 633-643

  Furlanetto, Sandra ^a   Orlandini, Serena ^a   Giannini, Iacopo ^a   Beretta, Giangiacomo ^b   Pinzauti, Sergio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Budesonide; Experimental design; Impurities; Mixed MEKC; Validation

Indexed keywords

BASELINE SEPARATION; BUDESONIDE; FIRST DESIGNS; MIXED MEKC; MULTIVARIATE OPTIMIZATION; OPTIMAL CONDITIONS; RELATED SUBSTANCES; SEPARATION PROCESS; SODIUM CHOLATE; VALIDATION;

STATISTICS;

14,15 DEHYDROBUDESONIDE; 16ALPHA HYDROXYPREDNISOLONE; 21 DEHYDROBUDESONIDE; BORIC ACID; BUDESONIDE; CHEMICAL COMPOUND; CHOLIC ACID; DEXTRO HOMOBUDESONIDE; ENTOCIR; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CONTROLLED STUDY; DRUG IMPURITY; DRUG STRUCTURE; ELECTRIC POTENTIAL; EXPERIMENTAL DESIGN; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; MICROEMULSION ELECTROKINETIC CHROMATOGRAPHY; PH MEASUREMENT; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT; VALIDATION PROCESS;

EID: 65249106086     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200800626     Document Type: Conference Paper

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