Chemotypic coverage: A new basis for constructing screening sublibraries

Journal of Chemical Information and Modeling

Volumn 49, Issue 3, 2009, Pages 531-542

  Johnson, Mark ^a   Shanmugasundaram, Veer ^b   Bundy, Gordon ^c   Chapman, Darryl ^d   Kilkuskie, Robert ^d  

^a Pannanugget Consulting   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c Independent Chemistry Consultant   (United States)

^d Michigan High Throughput Screening Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY;

CHEMOTYPES; CYCLIC SYSTEMS; ENHANCEMENT RATIOS; FOLLOW UP; NONOVERLAPPING; RING SYSTEMS; SAR DATA;

CHEMICAL ENGINEERING;

DIHYDROFOLATE REDUCTASE; ENZYME INHIBITOR;

ARTICLE; CHEMISTRY; DRUG EFFECT; STRUCTURE ACTIVITY RELATION;

ENZYME INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 65249096124     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci800250r     Document Type: Article

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