Evaluation of melatonin for prevention of radiation myelopathy in irradiated cervical spinal cord

Yakhteh

Volumn 11, Issue 1, 2009, Pages 43-48

  Shirazi, Alireza ^a   Haddadi, Gholam Hasan ^a,b   Ghazi Khansari, Mahmoud ^a   Abolhassani, Farid ^a   Mahdavi, Seied Rabie ^c   Eshraghyan, Mohmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b FASA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Melatonin; Myelopathy; Radiation; Spinal cord

Indexed keywords

GLUTATHIONE; MALONALDEHYDE; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CERVICAL MYELOPATHY; CERVICAL SPINAL CORD; COBALT THERAPY; CONTROLLED STUDY; DEMYELINATION; HISTOPATHOLOGY; MALE; NONHUMAN; PRIMARY PREVENTION; RADIATION INJURY; RADIATION PROTECTION; RAT;

EID: 65249094170     PISSN: 15614921     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Nieder C, Atman F, Price RE, Ang KK. Radiation myelopathy: New perspective on an old problem. Radiat Oncol Investig. 1999; 7: 193-203.
2. Mahdavi SR, Shirazi A, Minaee B, Nikoofar A, Mirzaee HR. Long-term changes of prostacyclin secretion in radiation-induced myelopathy. Reports of Practical Oncology and Radiotherapy. 2006; 11 (6): 273-279.
3. Shirazi A, Mahdavi SR, Minaee B, Nikoofar A, Azizi E. Short-term Changes in prostacyclin secretory profile of irradiated rat cervical spinal cord. Prostaglandins, Leukot Essenti Fatty Acids. 2005; 72: 373-378.
4. Shirazi A, Mahdavi SR, Trott KR. Radiation myelopathy: a radiobiological review. Reports of Practical Oncology and Radiotherapy. 2004; 9(4): 273-279.
5. Schulthesis TE, Kun LE, Ang KK, Stephens LC. Radiation response of the central nervous system. Int J Radiat Oncol Biol Phys. 1995; 31: 1093-1112.
6. Andratschke N, Nieder C, Price RE Rivera B, Tucker SL, Ang K. Modulation of rodent spinal cord radiation tolerance by administration of platelet-derived growth factor. Int J Radiat Oncol Biol Phys. 2004; 60:1257-1263.
7. Zaminy A, Ragerdi Kashani I, Barbarestani M, Hedayatpour A, Mahmoudi R, Vardasbi S, et al. Melatonin influences the proliferative and differentiative activity of rat adipoe-derived stem cells. Yakhteh. 2008; 10(1): 25-32.
8. Reiter RJ, Tan DX, Cebrera JD Arpa D. Melatonin tryptophan derivatives as free radical scavengers and antioxidant. Adv Exp Med Biol. 1999; 467: 379-387.
9. Pappolla MA, Sos M, Omar RA, Bick RJ, Hickson-Bick DL, Reiter RJ. Melatonin prevents death of neuroblastoma cells exposed to Alzheimer's amyloid peptide J. Neurol Sci. 1997; 17: 1683-1690.
10. Pablos MI, Gurrero JM, Ortiz GG, Agapito MT, Reiter RJ. Both melatonin and a putative nuclear melatonin in receptor against CGP 52608 stimulate glutathione peroxidative and glutathione reductase activities in mouse brain in vivo. Neuroendocrine Lett. 1997; 18: 49-58.
11. Fatih S, Erol C, Topsakal M, Faik O, Metin K, Nevin I. Protective effects of melatonin and vitamin E in brain damage due to gamma radiation. Neurosurg Rev. 2004; 27: 65-69.
12. Gul S, Celik S E, Kalayci M, Tasyurekli M, Cokar N, Bilge T. Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats. Surg Neurol. 2005; 64(4): 355-361.
13. Serin M, Gulbas H, Gures I, Sukru H, Yucel N. The histopathological evaluation of the effectiveness of melatonin as a protectant against acute lung injury induced by radiation therapy in a rat model. Int J Radiat Biol. 2007; 83(3): 187-193.
14. Wong CS, Vander Kogel J. Mechanisms of radiation injury to the central nervous system. Mol Inter. 2004; 4(5): 273-284.
15. Esterbauer H, Cheeseman K H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990; 186: 407-421.
16. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of Protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 7(72): 248-254.
17. Choi BH. Oxygen, antioxidants and brain dysfunction. Yonsei Med. 1993; 34: 1-10.
18. Kumar KS, Vaishnav YN, Weiss JF. Radioprotection by antioxidant enzymes and enzyme mimetics. Pharmacol Ther. 1989; 39: 301-309.
19. Ijichi A, Sakuma S, Weil MM, Tofilon PJ. Exvivo gene delivery of platelet-derived growth factor increases O-2° progenitors in adult rat spinal cord. Gene Ther. 1996; 3: 389-395.
20. Yuhas JM, Spellman JM, Culo F. The role of WR-2721 in radiotherapy and/ or chemotherapy. Cancer Clin Trials. 1980; 3: 211-216.
21. Reiter RJ. Antioxidant actions of melatonin. Adv Pharmacol in pharmacology. 1997; 38:103-117
22. Zhou G, Kawata T, Furasawa Y, Aoki M, Hirayama R, Ando K, et al. Protective effects of melatonin against low- and high-LET irradiation. J Radiat Res. 2006; 47: 175-181.
23. Shirazi A, Ghobadi G, Ghazi-khansari M. A radiobiological review on melatonin: A novel radioprotector. J Radiat. Res. 2007; 48: 263-272.
24. Vijalaxmi Meltz ML, Riter R J, Herman K S. Melatonin and protection from Whole-body irradiation: survival studies in mice. Mutat Res. 1999; 425: 21-27.
25. Vijalaxmi Reiter RJ, Meltz ML. Melatonin possible mechanisms involved in its 'radioprotective' effect. Mutat Res. 1998; 404: 187-189.
26. Erten S F, Kocak A, Ozdemir I, Aydemir S, Colak A, Reeder B S. Protective effect of melatonin on experimental spinal cord ischemia. Spinal cord. 2003; 41: 533-538.
27. Khan M, Griebel R. Acute spinal cord injury in the rat. Comparison of three experimental techniques. Can J Neurrosci. 1983; 10: 161-164.
28. Manda K, Ueno M, Anzai K. Melatonin mitigates oxidative damage and apoptosis in mouse cerebellum induced by high -LET 56Fe particle irradiation. J Pineal Res. 2008; 44(2): 189-196.
29. Sener G, Jahovice N, Tosum O, Atasoy BM, Yegen BC. Melatonin ameliorates ionizing radiation - induced oxidative organ damage in rats. Life Sci. 2003; 74: 563-272.
30. Reiter R J, Acuna-Castroviejo D, Tan D X, Burkhardt S. Free radical-mediated molecular damage: Mechanism for the protective actions of melatonin in the central nervous system. Ann New York Acad Sci. 2001; 200-209.
31. Blickenstaff RF, Brandstadter SM, Reddy S. Potential radioprotective agents: 1. Homologues of melatonin. J Pharm Sci. 1994; 83:216-218.