Stereochemical studies of hexylitaconic acid, an inhibitor of p53-HDM2 interaction

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 11, 2009, Pages 3027-3030

  Nakahashi, Atsufumi ^a   Miura, Nobuaki ^a   Monde, Kenji ^a   Tsukamoto, Sachiko ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

Alkyl carboxylic acid; Enantiomers; Enantioseparation; HDM2; p53; VCD

Indexed keywords

HEXYLITACONIC ACID; ITACONIC ACID; LACTONE; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEIN INTERACTION; STEREOCHEMISTRY;

CIRCULAR DICHROISM; HUMANS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-MDM2; STEREOISOMERISM; SUCCINATES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 65149103956     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.04.057     Document Type: Article

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