Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix

Fertility and Sterility

Volumn 91, Issue 5 SUPPL., 2009, Pages 2172-2176

  Khazaei, Mozafar ^a   Montaseri, Azadeh ^a   Casper, Robert F ^b  

^a KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

aromatase inhibitors; endometriosis; fibrin matrix; human endometrium; in vitro culture; Letrozole

Indexed keywords

LETROZOLE;

ANGIOGENESIS; ARTICLE; BIOLOGICAL MODEL; CONTROLLED STUDY; DRUG EFFECT; ENDOMETRIOSIS; ENDOMETRIUM BIOPSY; EXPLANT; GROWTH STIMULATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; TISSUE CULTURE;

AROMATASE INHIBITORS; CELL CULTURE TECHNIQUES; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOMETRIOSIS; ENDOMETRIUM; FEMALE; FIBRIN; HUMANS; HYSTERECTOMY; NITRILES; PREMENOPAUSE; TRIAZOLES;

EID: 65049090789     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.02.090     Document Type: Article

References (33)

1. Vessey M.P., Villard-Mackintosh L., and Painter R. Epidemiology of endometriosis in women attending family planning clinics. Br Med J 306 (1993) 182-184
2. Fasciani A., Bocci G., Xu J., Bielecki R., Greenblatt E., Leyland N., et al. Three dimensional cultures of endometrial explants mimic the early stage of endometriosis. Fertil Steril 80 (2003) 1137-1143
3. Awwad J.T., Sayegh R.A., Hassan T., Awwad S.T., and Isaacson K. The SCID mouse: an experimental model for endometriosis. Hum Reprod 14 (1999) 3107-3111
4. D'Hooghe T.M. Clinical relevance of the baboon as a model for the study of endometriosis. Fertil Steril 68 (1997) 613-625
5. Fazaleabas A.T., Brudney A., Gurates B., Chai D., and Bulun S. A modified baboon model for endometriosis. Ann N Y Acad Sci 995 (2002) 308-317
6. Bruner-Tran K.L., Webster-Clair D., and Osteen K. Experimental endometriosis: the nude mouse as a xenograft host. Ann N Y Acad Sci 955 (2002) 328-339
7. Tabibzadeh S., Miller S., Doson W.C., and Satyaswaroop P.G. An experimental model for endometriosis in athymic mice. Front Biosci 4 (1999) 4-9
8. Khazaei M., Esfandiari N., Javed M., Gotlieb L., and Casper R.F. Successful human secretory phase endometrium culture as an in vitro model for endometriosis. [abstract]. Fertil Steril 82 (2004) S164
9. Esfandiari N., Ai J., Nezemin Z., Javed M., Gotlieb L., and Casper R.F. Expression of glycodelin and cyclooxygenase-2 in human endometrial tissue following three-dimensional culture. Am J Reprod Immunol 54 (2007) 49-54
10. Ebert A.D., Bartley J., and David M. Aromatase inhibitors and cyclooxygenase-2(COX-2) inhibitors in endometriosis: new question-old answer?. Eur J Obstet Gynecol Reprod Biol 122 (2005) 144-150
11. Esfandiari N., Khazaei M., Ai J., Bielecki R., Gotlieb L., Ryan E., et al. Effect of a statin on an in vitro model of endometriosis. Fertil Steril 87 (2007) 257-262
12. Montaseri A., Khazaei M., Ghorbani R., and Rezaei M. Atorvastatin effect on human endometrium cultured in three-dimensional matrix. [in Persian]. Iranian Fertil Steril J 7 (2007) 385-66
13. Simpson E.R., Mahendroo M.S., Means G.D., Kilgore M.W., Hinshelwood M.M., Graham-Lorence S., et al. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr Rev 15 (1994) 342-355
14. Noble L.S., Simpson E.R., John A., and Bulun S.E. Aromatase expression in endometriosis. J Clin Endocrinol Metab 81 (1996) 174-179
15. Bulun S.E., Gurates B., Fang Z., Tamura M., Sebastian S., Zhou J., et al. Mechanisms of excessive estrogen formation in endometriosis. J Reprod Immunol 55 (2002) 21-33
16. Attar E., and Bulun S.E. Aromatase inhibitors: the next generation of therapeutics for endometriosis?. Fertil Steril 85 (2006) 1307-1318
17. Bocci G., Fassiani A., Dansei R., Viacava P., Genazzani A.R., and Del Tacca M. In-vitro evidence of autocrine secretion of vascular growth factor by endothelial cells from human placental blood vessels. Mol Hum Reprod 7 (2001) 771-777
18. Milingos D., Katopodis H., Milingos S., Protopapas A., Creatsas G., Michalas S., et al. Insulin-like growth factor-1 isoform mRNA expression in women with endometriosis: eutopic endometrium versus endometriotic cyst. Ann N Y Acad Sci 1092 (2006) 434-439
19. Bajetta E., Ferrari L., Celio L., Mariani L., Miceli R., Di Leo A., et al. The aromatase inhibitor letrozole in advanced breast cancer: effects on serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 levels. J Steroid Biochem Mol Biol 63 (1997) 261-267
20. Talavera F., Reynolds R.K., Roberts J.A., and Menon M.J. Insulin-like growth factor I receptors in normal and neoplastic human endometrium. Cancer Res 50 (1990) 3019-3024
21. Murphy L.J., Murphy L.C., and Friesen H.G. Estrogen induces insulin-like growth factor-I expression in rat uterus. Mol Endocrinol 1 (1987) 445-450
22. Mitwally M.F., and Casper R.F. Aromatase inhibitors for ovulation stimulation: future avenues for infertility. Curr Opin Obstet Gynecol 14 (2002) 255-263
23. Cortinez A., De-Carvalho I., Vantman D., Gabler F., Iniguez G., and Vega M. Hormonal profile and endometrial morphology in letrozole controlled ovarian hyperstimulation in ovulatory infertile patients. Fertil Steril 83 (2005) 110-115
24. Sammour A., Biljan M.M., Tan S.L., and Tulandi T. Prospective randomized trial comparing the effect of letrozole and clomiphene citrate on follicular development, endometrial thickness and pregnancy rate in patients undergoing super-ovulation prior to intrauterine insemination (IUI). [abstract]. Fertil Steril 76 (2001) S110
25. Mitwally M.F., and Casper R.F. Use of aromatase inhibitors for ovulation stimulation of ovulation in patients with an inadequate response to clomiphene citrate. Fertil Steril 75 (2001) 305-309
26. Mitwally M.F., and Casper R.F. Aromatase inhibition improves ovarian response to FSH dose: a potential option for low responders during ovulation stimulation. Fertil Steril 77 (2002) 776-780
27. Garcia-Velasco J.A., Moreno L., Pacheco A., Guillén A., Duque L., Requena A., et al. The aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in vitro fertilization outcome in low responder patients: a pilot study. Fertil Steril 84 (2005) 82-87
28. Arici A. The role of endometrium in endometriosis. J Soc Gynecol Invest 13 (2006) 467-476
29. Bulun S., Imir G., Utsunomiya H., Thung S., Gurates B., Tamura M., et al. Aromatase in endometriosis and uterine leiomyoma. J of Steroid Biochem Mol Biol 95 (2005) 57-62
30. Olive D.L., and Schwartz L.B. Endometriosis. N Eng J Med 328 (1993) 1759-1769
31. Khorram O., Taylor R.N., Taylor I.P., Schall T.J., and Landers D.V. Peritoneal fluid concentration of the cytokine RANTES correlate with the severity of endometriosis. Am J Obstet Gynecol 169 (1993) 1545-1549
32. Bruner K.L., Matrisian L.M., Rogers W.H., Gorstein F., and Osteen K.J. Suppression of matrix metalloproteinase inhibits establishment of ectopic lesions by human endometrium in nude mice. J Clin Invest 99 (1997) 2851-2857
33. Zeitoun K., Takayama K., Sasano H., Suzuki T., Moghrabi N., Andersson S., et al. Deficient 17beta-hydroxysteroid dehydrogenase type 2 express in endometriosis: failure to metabolize 17beta-estradiol. J Clin Endocrinol Metab 83 (1998) 4474-4480