Effect of a statin on an in vitro model of endometriosis

Fertility and Sterility

Volumn 87, Issue 2, 2007, Pages 257-262

  Esfandiari, Navid ^a   Khazaei, Mozafar ^a   Ai, Jafar ^a   Bielecki, Ryszard ^a   Gotlieb, Lynda ^a   Ryan, Edward ^a   Casper, Robert F ^a  

^a Toronto Centre for Advanced Reproductive Technology   (Canada)

Author keywords

angiogenesis; Endometriosis; fibrin matrix; in vitro; invasion; statin

Indexed keywords

FIBRIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; STATINE DERIVATIVE;

ADULT; ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL GROWTH; CELL INVASION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOMETRIOSIS; ENDOMETRIUM BIOPSY; FEMALE; FEMALE INFERTILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; OVULATION; PATHOGENESIS; PRIORITY JOURNAL; STROMA CELL; UTERUS CAVITY;

ADULT; ANGIOGENESIS INHIBITORS; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOMETRIOSIS; FEMALE; HUMANS; LOVASTATIN; NEOVASCULARIZATION, PATHOLOGIC;

EID: 33846671111     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.06.040     Document Type: Article

References (16)

1. Strathy J.H., Molgaard C.A., Coulam C.B., and Melton L.J. Endometriosis and infertility-a laparoscopic study of endometriosis among fertile and infertile women. Fertil Steril 38 (1982) 667-672
2. Kettel L.M., and Hummel W.P. Modern medical management of endometriosis. Obstet Gynecol Clin North Am 24 (1997) 361-373
3. Adamson G.D., and Nelson H.P. Surgical treatment of endometriosis. Obstet Gynecol Clin North Am 24 (1997) 375-409
4. Giudice L.C., and Kao L.C. Endometriosis. Lancet 364 (2004) 1789-1799
5. Norrby K. Angiogenesis-new aspects relating to its initiation and control. APMIS 105 (1997) 417-437
6. Skaletz-Rorowski A., and Walsh K. Statin therapy and angiogenesis. Curr Opin Lipidol 14 (2003) 599-603
7. Fasciani A., Bocci G., Xu J., Bielecki R., Greenblatt E., Leyland N., et al. Three-dimensional in vitro culture of endometrial explants mimics the early stages of endometriosis. Fertil Steril 80 (2003) 1137-1143
8. D'Hooghe T.M. Clinical relevance of the baboon as a model for the study of endometriosis. Fertil Steril 68 (1997) 613-625
9. Zamah N.M., Dodson M.G., Stephens L.C., Buttram V.C., Besch P.K., and Kaufman R.H. Transplantation of normal and ectopic human endometrial tissue into athymic nude mice. Am J Obstet Gynecol 149 (1984) 591-597
10. Nisolle M., Casanas-Roux F., and Donnez J. Early-stage endometriosis-adhesion and growth of human menstrual endometrium in nude mice. Fertil Steril 74 (2000) 306-2
11. Laschke M.W., Elitzsch A., Vollmar B., and Menger M.D. In vivo analysis of angiogenesis in endometriosis-like lesions by intravital fluorescence microscopy. Fertil Steril 84 Suppl 2 (2005) 1199-1209
12. Folkman J. Antiangiogenesis in cancer therapy-endostatin and its mechanisms of action. Exp Cell Res 312 5 (2006) 594-607
13. Vincent L., Chen W., Hong T., Mirshahi F., Mishal Z., Mirshahi-Khorassani T., et al. Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effect. FEBS Lett 495 (2001) 159-166
14. Kureishi Y., Luo Z., Shiojima I., Bialik A., Fulton D., Lefer D.J., et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase akt and promotes angiogenesis in normocholesterolemic animals. Nat Med 6 (2000) 1004-1010
15. Weis M., Heeschen C., Glassford A., and Cooke J. Statins have biphasic effects on angiogenesis. Circulation 105 (2002) 739-745
16. Bedaiwy M.A., Falcone T., Mascha E.J., and Casper R.F. Genetic polymorphism in the fibrinolytic system and endometriosis. Obstet Gynecol 108 1 (2006) 162-168