Sauvatide - A novel amidated myotropic decapeptide from the skin secretion of the waxy monkey frog, Phyllomedusa sauvagei

Biochemical and Biophysical Research Communications

Volumn 383, Issue 2, 2009, Pages 240-244

  Wang, Lei ^a   Zhou, Mei ^a   Zhou, Zhihao ^a   Chen, Tianbao ^a   Walker, Brian ^a   Shaw, Chris ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Amphibian; Cloning; Peptide; Skin; Smooth muscle

Indexed keywords

AMIDE; COMPLEMENTARY DNA; PEPTIDE DERIVATIVE; SAUVATIDE; UNCLASSIFIED DRUG;

AMIDATION; ANIMAL TISSUE; ARTICLE; BLADDER; CARBOXY TERMINAL SEQUENCE; CHROMATOGRAPHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; FROG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PHYLLOMEDUSA SAUVAGEI; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SKIN SECRETION; SMOOTH MUSCLE CONTRACTION;

AMINO ACID SEQUENCE; ANIMALS; ANURA; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OLIGOPEPTIDES; RATS; SKIN; URINARY BLADDER;

AMPHIBIA; ANURA; MAMMALIA; PHYLLOMEDUSA SAUVAGEI; RATTUS;

EID: 65049089288     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.04.003     Document Type: Article

References (12)

1. Erspamer V. Bioactive secretions of the integument. In: Heatwole H., and Barthalmus G.T. (Eds). Amphibian Biology, vol. 1. The Integument (1994), Surrey Beatty, Chipping Norton 179-350
2. Daly J.W., and Spande T.F. Amphibian alkaloids: chemistry, pharmacology and biology. In: Pelletier S.W. (Ed). Alkaloids: "Chemical and Biological Perspectives", vol. 4 (1986), Wiley, New York 1-274
3. Basir Y.J., and Conlon J.M. Peptidomic analysis of the skin secretions of the pickerel frog Rana palustris identifies six novel families of structurally related peptides. Peptides 24 (2003) 379-383
4. Wang L., Zhou M., McClelland A., Reilly A., Chen T., Gagliardo R., Walker B., and Shaw C. Novel dermaseptin, adenoregulin and caerin homologs from the Central American red-eyed leaf frog, Agalychnis callidryas, revealed by functional peptidomics of defensive skin secretion. Biochimie 90 (2008) 1435-1441
5. Song G., Zhou M., Chen W., Chen T., Walker B., and Shaw C. HV-BBI - a novel amphibian skin Bowman-Birk-like trypsin inhibitor. Biochem. Biophys. Res. Commun. 372 (2008) 191-196
6. Erspamer V., Melchiorri P., Falconieri Erspamer G., Montecucchi P.C., and De Castiglione R. Phyllomedusa skin: a huge factory and store-house of a variety of active peptides. Peptides 6 (1985) 7-12
7. Bevins B.L., and Zasloff M. Peptides from frog skin. Annu. Rev. Biochem. 59 (1990) 395-414
8. Lazarus L.H., and Atilla M. The toad, ugly and venomous, wears yet a precious jewel in his skin. Prog. Neurobiol. 41 (1993) 473-507
9. Severini C., Improta G., Falconieri-Erspamer G., Salvadori S., and Erspamer V. The tachykinin peptide family. Pharmacol. Rev. 54 (2002) 285-322
10. Apponyi M.A., Pukala T.L., Brinkworth C.S., Maselli V.M., Bowie J.H., Tyler M.J., Booker G.W., Wallace J.C., Carver J.A., Separovic F., Doyle J., and Llewellyn L.E. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides 25 (2004) 1035-1054
11. Prado V.H.M., Borges R.E., Silva F.R., Tognolo T.T., and Rossa-Feres D.C. Amphibia, Anura, Hylidae, Phyllomedusa azurea - distribution extension. Check List 4 (2008) 55-56
12. Thompson A.H., Bjourson A.J., Orr D.F., Shaw C., and McClean S. Amphibian skin secretomics: application of parallel quadrupole time-of-flight mass spectrometry and peptide precursor cDNA cloning to rapidly characterize the skin secretory peptidome of Phyllomedusa hypochondrialis azurea: discovery of a novel peptide family, the hyposins. J. Proteome Res. 9 (2007) 3604-3613