(S)-reticuline induces vasorelaxation through the blockade of L-type Ca2+ channels

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 379, Issue 2, 2009, Pages 115-125

  Medeiros, Marcos Antônio A ^a,b   Nunes, Xirley P ^a   Barbosa Filho, José M ^a   Lemos, Virginia S ^b   Pinho, José F ^b   Roman Campos, Danilo ^b   De Medeiros, Isac A ^a   Araújo, Demetrius Antonio M ^a   Cruz, Jader S ^b  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

(S) reticuline; A7r5 cells; Calcium currents; Patch clamp; Rat aorta

Indexed keywords

ADENYLATE CYCLASE ACTIVATOR; BUCLADESINE; CALCIUM CHANNEL L TYPE; CALCIUM CHLORIDE; FORSKOLIN; POTASSIUM CHLORIDE; RETICULINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL ACTIVITY; CELL DENSITY; CELL LINE; CELL STRAIN A7R5; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; EMBRYO; MALE; MEDICINAL PLANT; MUSCLE CONTRACTION; NONHUMAN; OCOTEA DUCKEI; PATCH CLAMP; RAT; SMOOTH MUSCLE FIBER; STEADY STATE; TENSION; VASODILATATION;

ADENYLATE CYCLASE; ANIMALS; AORTA; BENZYLISOQUINOLINES; BUCLADESINE; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; ENZYME ACTIVATION; FORSKOLIN; MALE; MEMBRANE POTENTIALS; MUSCLE RELAXATION; MUSCLE, SMOOTH; OCOTEA; PATCH-CLAMP TECHNIQUES; PLANT EXTRACTS; RATS; RATS, WISTAR; STEREOISOMERISM; VASODILATION;

EID: 64949195477     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0352-1     Document Type: Article

References (35)

1. BP Bean 1984 Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state Proc Natl Acad Sci U S A 81 6388 6392
2. F Bezanilla CM Armstrong 1977 Inactivation of the sodium channel. I. Sodium current experiments J Gen Physiol 70 549 566
3. L Bilcikova V Bauer J Colena 1987 The effect of methylxanthines, etymozol, ephredrine and papaverine on guinea pig and dog trachea Gen Physiol Biophys 6 137 148
4. i in vascular smooth muscle by inhibition of the calcium current Cell Calcium 15 2 122 131
5. TB Bolton 1979 Mechanism of action of transmitters and other substances on smooth muscle Physiol Rev 59 606 718
6. 2+ channels in vascular smooth muscle: multiple functions Cell Calcium 40 221 230
7. AP de Oliveira FF Furtado MS da Silva JF Tavares RA Mafra DA Araújo JS Cruz IA de Medeiros 2006 Calcium channel blockade as a target for the cardiovascular effects induced by the 8 (17), 12E, 14-labdatrien-18-oic acid (labdane-302) Vascul Pharmacol 44 338 344
8. KLG Dias C Da Silva Dias JM Barbosa-Filho RN Almeida N De Azevedo Correia IA Medeiros 2004 Cardiovascular effects induced by reticuline in normotensive rats Planta Med 70 328 333
9. 2+ channel via superoxide anion generation Br J Pharmacol 133 988 996
10. 2+ channels in A7r5 cells by physiological levels of testosterone Endocrinology 147 2675 2680
11. Hille B (2001) Ion channels of excitable membranes, 3rd edn. Sinauer, Sunderland, MA, USA
12. 2+ current in isolated smooth muscle cells from the guinea pig trachea J Pharmacol Exp Ther 263 194 200
13. 2+ channels by cAMP and cGMP in vascular smooth muscle cells Circ Res 73 6 1128 1137
14. K Jim A Harris LB Rosenberger DJ Triggle 1981 Stereoselective and non-stereoselective effects of D-600 (methoxyverapamil) in smooth-muscle preparations Eur J Pharmacol 76 67 72
15. T Kaneda K Shimizu S Nakajyo N Urakawa 1998 The difference in the inhibitory mechanisms of papaverine on vascular and intestinal smooth muscles Eur J Pharmacol 355 149 157
16. J Kaur NN Ghosh R Chandra 2004 Synthesis and antispasmodic activity evaluation of bis-(papaverine) analogues Chem Pharm Bull (Tokyo) 52 316 321
17. I Kimura M Kimura M Yoshizadi K Yanada S Kadota T Kikuchi 1983 Neuromuscular blocking action of alkaloids from a japanese crude drug "SHIN-I" (FLOSMAGNOLIAE) in frog skeletal muscle Planta Med 48 43 47
18. 2+ channel in aortic smooth muscle-derived A7r5 cells Cell Signal 12 63 70
19. AA Kochegarov 2003 Pharmacological modulators of voltage-gated calcium channels and their therapeutical application Cell Calcium 33 145 162
20. JN Lorenz DR Bielefeld N Sperelakis 1994 Regulation of calcium channel current in A7r5 vascular smooth muscle cells by cyclic nucleotides Am J Physiol 266 35 C1656 C1663
21. ML Martin JA Sagredo JM Morais J Montero MT Sanchez L San Roman 1988 Uterine inhibitory effect of reticuline J Pharmacol 40 801 802
22. ML Martin MT Diaz MJ Montero P Prieto LS Roman D Cortes 1993 Antispasmodic activite of beszylisoquinoline alkaloids analogous to papaverine Planta Med 59 63 67
23. 2+ channels of the A7r5 smooth muscle-derived cell line Cell Signal 9 367 372
24. S Moncada RMJ Palmer EA Higgs 1991 Nitric oxide; physiology, pathophysiology, and pharmacology Pharmacol Rev 43 109 142
25. LCSL Morais JM Barbosa-Filho RN Almeida 1998 Central depressant effects of reticuline extracted from Ocotea duckei in rats and mice J Ethnopharmacol 62 57 61
26. MT Nelson NB Standen JF Worley 1988 Noradrenaline contracts arteries by activating voltage-dependent calcium channels Nature 336 3382 3385
27. TO Neild N Kotecha 1987 Relation between membrane potential and contractile force in smooth muscle of the rat tail artery during stimulation by norepinephrine, 5-hydroxytryptamine, and potassium Circ Res 60 791 795
28. MC Sanguinetti RS Kass 1984 Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists Circ Res 55 336 348
29. SM Taylor H Downes 1982 Bronchodilator mechanisms in bullfrog lung: differences in response to isoproterenol, theophylline and papaverine J Pharmacol Exp Ther 223 359 367
30. A Uehara JR Hume 1985 Interactions of organic calcium channel antagonists with calcium channels in single frog atrial cells J Gen Physiol 85 621 647
31. 2+ channels in A7r5 cells by cilnidipine and its derivatives Jpn J Pharmacol 85 260 270
32. v1.2 Biochem Biophys Res Commun 361 522 527
33. P Vuorela M Leinonen P Saikku P Tammela JP Rauha T Wennberg H Vuorela 2004 Natural products in the process of finding new drug candidates Curr Med Chem 11 1375 1389
34. H Watanabe M Ikeda K Qatanabe T Kikuchi 1981 Effects on central dopaminergic systems of D-coclaurine and D-reticuline, extracted from magnolia salicifolia Planta Med 42 213 222
35. 2+ currents in A7r5 vascular smooth muscle cell line Am J Physiol 266 C975 C980