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Volumn 44, Issue 4, 2009, Pages 395-400

Enzyme kinetics of ligustilide metabolism in rat liver microsomes

Author keywords

Enzyme kinetics; Ligustilide; Liver microsomes

Indexed keywords

4 METHYLPYRAZOLE; ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; KETOCONAZOLE; LIGUSTILIDE; NITRENDIPINE; OMEPRAZOLE; QUINIDINE; TRIMETHOPRIM;

EID: 64949188638     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (11)
  • 1
    • 34247263984 scopus 로고    scopus 로고
    • Relaxation effects of ligustilide and senkyunolide A, two main constitants of Ligusticum chuanxiong, in rat isolated aorta [J]
    • Chan SS, Cheng TY, Lin G. Relaxation effects of ligustilide and senkyunolide A, two main constitants of Ligusticum chuanxiong, in rat isolated aorta [J]. J Ethnopharmacol, 2007, 111:677-680.
    • (2007) J Ethnopharmacol , vol.111 , pp. 677-680
    • Chan, S.S.1    Cheng, T.Y.2    Lin, G.3
  • 3
    • 27644591372 scopus 로고    scopus 로고
    • Screening, analysis and in vitro vasodilatation of effective components from Ligusticum chuanxiong [J]
    • Liang MJ, He LC, Yang GD. Screening, analysis and in vitro vasodilatation of effective components from Ligusticum chuanxiong [J], Life Sci, 2005, 78: 128-133.
    • (2005) Life Sci , vol.78 , pp. 128-133
    • Liang, M.J.1    He, L.C.2    Yang, G.D.3
  • 4
    • 33746387005 scopus 로고    scopus 로고
    • Neuroprotective role of Z-ligustilide against forebrain ischemic injury in ICR mice [J]
    • Kuang X, Yao Y, Du JR, et al. Neuroprotective role of Z-ligustilide against forebrain ischemic injury in ICR mice [J]. Brain Res, 2006, 1102: 145-153.
    • (2006) Brain Res , vol.1102 , pp. 145-153
    • Kuang, X.1    Yao, Y.2    Du, J.R.3
  • 5
    • 64949197520 scopus 로고    scopus 로고
    • Therapeutic effects and its mechanism of angelica lactone on focal cerebral ischemia in rats [J]
    • Zhang GY, Du JR, Kuang X, et al. Therapeutic effects and its mechanism of angelica lactone on focal cerebral ischemia in rats [J]. West China J Pharm Sci 2006, 21: 114-117.
    • (2006) West China J Pharm Sci , vol.21 , pp. 114-117
    • Zhang1    GY, D.J.2    Kuang, X.3
  • 6
    • 33846948242 scopus 로고    scopus 로고
    • Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats [J]
    • Peng HY, Du JR, Zhang GY, et al. Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats [J]. Biol Pharm Bull, 2007, 30: 309-312.
    • (2007) Biol Pharm Bull , vol.30 , pp. 309-312
    • Peng1    HY, D.J.2    Zhang, G.Y.3
  • 7
    • 33746000417 scopus 로고    scopus 로고
    • Ligustilide inhibits vascular smooth muscle cells proliferation [J]
    • Lu Q, Qiu TQ, Yang H. Ligustilide inhibits vascular smooth muscle cells proliferation [J], Eur J Pharmacol, 2006, 542: 136-140.
    • (2006) Eur J Pharmacol , vol.542 , pp. 136-140
    • Lu, Q.1    Qiu, T.Q.2    Yang, H.3
  • 8
    • 0029018915 scopus 로고
    • Comparison of influence of essential oil from Ligusticum Chuanxiong Hoert. on microcirculation in rabit conjunctive bulblar before and after decomposition of ligustilide [J]
    • Shi LF, Zhang XM. Comparison of influence of essential oil from Ligusticum Chuanxiong Hoert. on microcirculation in rabit conjunctive bulblar before and after decomposition of ligustilide [J], Chin J Pharmacol Toxicol 1995, 9: 157-158.
    • (1995) Chin J Pharmacol Toxicol , vol.9 , pp. 157-158
    • Shi, L.F.1    Zhang, X.M.2
  • 9
    • 38749153569 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of ligustilide, a major bioactive component in Rhizoma Chuanxiong, in the rat [J]
    • Yan R, Ko NL, Li SL. Pharmacokinetics and metabolism of ligustilide, a major bioactive component in Rhizoma Chuanxiong, in the rat [J]. Drug Metab Dispos, 2008, 36: 400-408.
    • (2008) Drug Metab Dispos , vol.36 , pp. 400-408
    • Yan, R.1    Ko, N.L.2    Li, S.L.3
  • 11
    • 64949101526 scopus 로고    scopus 로고
    • Hangzhou: Zhejiang University Press
    • Zeng S. Drug Metablism [M]. Hangzhou: Zhejiang University Press, 2004: 264-265.
    • (2004) Drug Metablism [M] , pp. 264-265
    • Zeng, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.