Physical activity, inflammatory biomarkers in gingival crevicular fluid and periodontitis

Journal of Clinical Periodontology

Volumn 36, Issue 5, 2009, Pages 388-395

  Sanders, Anne E ^a,b   Slade, Gary D ^b   Fitzsimmons, Tracy R ^a   Bartold, Peter Mark ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Epidemiology; Exercise; Inflammatory biomarkers; Periodontal disease; Protective effect

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 1BETA;

ADULT; AGE; ARTICLE; AUSTRALIA; BODY MASS; CASE CONTROL STUDY; CHEMISTRY; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; EPIDEMIOLOGY; EXERCISE; FEMALE; GINGIVA DISEASE; GINGIVITIS; HEALTH SURVEY; HUMAN; IMMUNOLOGY; LEISURE; MALE; MOTOR ACTIVITY; PERIODONTAL DISEASE; PERIODONTITIS; RISK ASSESSMENT; SMOKING;

ADULT; AGE FACTORS; AUSTRALIA; BIOLOGICAL MARKERS; BODY MASS INDEX; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; EPIDEMIOLOGIC STUDIES; EXERCISE; FEMALE; GINGIVAL CREVICULAR FLUID; GINGIVAL RECESSION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; LEISURE ACTIVITIES; MALE; MOTOR ACTIVITY; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PERIODONTITIS; POPULATION SURVEILLANCE; RISK ASSESSMENT; SMOKING;

EID: 64949085528     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2009.01394.x     Document Type: Article

References (39)

1. Abdellatif, H. M. Burt, B. A. (1987) An epidemiological investigation into the relative importance of age and oral hygiene status as determinants of periodontitis. Journal of Dental Research 66, 13 18.
2. Abramson, J. L. Vaccarino, V. (2002) Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults. Archives of Internal Medicine 162, 1286 1292.
3. Al-Zahrani, M. S., Borawski, E. A. Bissada, N. F. (2005a) Increased physical activity reduces prevalence of periodontitis. Journal of Dentistry 33, 703 710.
4. Al-Zahrani, M. S., Borawski, E. A. Bissada, N. F. (2005b) Periodontitis and three health-enhancing behaviors: maintaining normal weight, engaging in recommended level of exercise, and consuming a high-quality diet. Journal of Periodontology 76, 1362 1366.
5. Armstrong, T., Bauman, A. Davies, J. (2000) Physical Activity Patterns of Australian Adults. Results of the 1999 National Physical Activity Survey. Canberra : Australian Institute of Health and Welfare.
6. Australian Institute of Health and Welfare (AIHW) (2003) The Active Australia Survey: A Guide and Manual for Implementation, Analysis and Reporting. Canberra : AIHW.
7. Beck, J. D., Offenbacher, S., Williams, R., Gibbs, P. Garcia, R. (1998) Periodontitis: a risk factor for coronary heart disease? Annals of Periodontology 3, 127 141.
8. Booth, M., Owen, N., Bauman, A. Gore, C. (1996a) Relationship between a 14-day recall measure of leisure time physical activity and a submaximal test of physical work capacity in a population sample of Australian adults. Research Quarterly for Exercise and Sport 67, 221 227.
9. Booth, M., Owen, N., Bauman, A. Gore, C. (1996b) Retest reliability of recall measures of leisure time physical activity in Australian adults. International Journal of Epidemiology 25, 153 159.
10. Brown, W. J., Trost, S. G., Bauman, A., Mummery, K. Owen, N. (2004) Test-retest reliability of four physical activity measures used in population surveys. Journal of Science and Medicine in Sport 7, 205 215.
11. Bulut, U., Develioglu, H., Taner, I. L. Berker, E. (2001) Interleukin-1 beta levels in gingival crevicular fluid in type 2 diabetes mellitus and adult periodontitis. Journal of Oral Science 43, 171 177.
12. Elosua, R., Bartali, B., Ordovas, J. M., Corsi, A. M., Lauretani, F. Ferrucci, L. (2005) InCHIANTI investigators. Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 60, 760 767.
13. Fitzsimmons, T. R., Sanders, A. E., Slade, G. D. Bartold, P. M. (In press) Biomarkers of periodontal inflammation in the Australia adult population. Australian Dental Journal.
14. Ford, E. S. (2002) Does exercise reduce inflammation? Physical activity and C-reactive protein among US adults. Epidemiology 13, 561 568.
15. Genco, R. J. (1996) Current view of risk factors for periodontal diseases. Journal of Periodontology 67, 1041 1049.
16. Joshipura, K. J., Wand, H. C., Merchant, A. T. Rimm, E. B. (2004) Periodontal disease and biomarkers related to cardiovascular disease. Journal of Dental Research 83, 151 155.
17. Kasapis, C. Thompson, P. D. (2005) The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review. Journal of the American College of Cardiology 45, 1563 1569.
18. Li, X., Kolltveit, K. M., Tronstad, L. Olsen, I. (2000) Systemic diseases caused by oral infection. Clinical Microbiology Reviews 13, 547 558.
19. Linden, G. J., McClean, K., Young, I., Evans, A. Kee, F. (2008) Persistently raised C-reactive protein levels are associated with advanced periodontal disease. Journal of Periodontology 35, 741 747.
20. Makita, S., Nakamura, M., Satoh, K., Tanaka, F., Onoda, T., Kawamura, K., Ohsawa, M., Tanno, K., Itai, K., Sakata, K., Okayama, A., Terayama, Y., Yoshida, Y. Ogawa, A. (2008) Serum C-reactive protein levels can be used to predict future ischemic stroke and mortality in Japanese men from the general population. Atherosclerosis August 12. [Epub ahead of print].
21. Masada, M. P., Persson, R., Kenney, J. S., Lee, S. W., Page, R. C. Allison, A. C. (1990) Measurement of interleukin-1 alpha and -1 beta in gingival crevicular fluid: implications for the pathogenesis of periodontal disease. Journal of Periodontal Research 25, 156 163.
22. Medzhitov, R. (2007) Recognition of microorganisms and activation of the immune response. Nature 449, 819 826.
23. Medzhitov, R. (2008) Origin and physiological roles of inflammation. Nature 24, 428 435.
24. Merchant, A. T., Pitiphat, W., Rimm, E. B. Joshipura, K. (2003) Increased physical activity decreases periodontitis risk in men. European Journal of Epidemiology 18, 891 898.
25. Nunn, M. E. (2003) Understanding the etiology of periodontitis: an overview of periodontal risk factors. Periodontology 2000 32, 11 23.
26. Page, R. C. Eke, P. I. (2007) Case definitions for use in population-based surveillance of periodontitis. Journal of Periodontology 78, 1387 1399.
27. Pai, J. K. Pischon, T., Ma, J., Manson, J. E., Hankinson, S. E., Joshipura, K., Curhan, G. C., Rifai, N., Cannuscio, C. C., Stampfer, M. J. Rimm, E. B. (2004) Inflammatory markers and the risk of coronary heart disease in men and women. New England Journal of Medicine 351, 2599 2610.
28. Paraskevas, S., Huizinga, J. D. Loos, B. G. (2008) A systematic review and meta-analyses on C-reactive protein in relation to periodontitis. Journal of Clinical Periodontology 35, 277 290.
29. Pradhan, A. D., Manson, J. E., Rifai, N., Buring, J. E. Ridker, P. M. (2001) C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. Journal of the American Medical Association 286, 327 334.
30. Pradhan, A. D., Manson, J. E., Rossouw, J. E., Siscovick, D. S., Mouton, C. P., Rifai, N., Wallace, R. B., Jackson, R. D., Pettinger, M. B. Ridker, P. M. (2002) Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study. Journal of the American Medical Association 288, 980 987.
31. Slade, G. D., Spencer, A. J. Roberts-Thomson, K. F. (eds) 2007) Australia's Dental Generations: the National Survey of Adult Oral Health 2004-06 (Dental Statistics and Research Series No. 34). Canberra : Australian Institute of Health and Welfare, available at: (accessed 20 November 2008).
32. Stashenko, P., Fujiyoshi, P., Obernesser, M. S., Prostak, L., Haffajee, A. D. Socransky, S. S. (1991) Levels of interleukin 1 beta in tissue from sites of active periodontal disease. Journal of Clinical Periodontology 18, 548 554.
33. Timperio, A., Salmon, J., Rosenberg, M. Bull, F. C. (2004) Do logbooks influence recall of physical activity in validation studies? Medicine and Science in Sports and Exercise 36, 1181 1186.
34. Tüter, G., Kurtis, B. Serdar, M. (2007) Evaluation of gingival crevicular fluid and serum levels of high-sensitivity C-reactive protein in chronic periodontitis patients with or without coronary artery disease. Journal of Periodontology 78, 2319 2324.
35. United States Department of Health and Human Services. (1996) Physical Activity and Health: A Report of the Surgeon General, pp. 11 37. Atlanta, GA : US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion.
36. Wakai, K., Kawamura, T., Umemura, O., Hara, Y., Machida, J., Anno, T., Ichihara, Y., Mizuno, Y., Tamakoshi, A., Lin, Y., Nakayama, T. Ohno, Y. (1999) Associations of medical status and physical fitness with periodontal disease. Journal of Clinical Periodontology 26, 664 672.
37. World Health Organization (2000) Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation. Technical Report Series 894. Geneva : WHO.
38. Yates, T., Davies, M., Brady, E., Webb, D., Gorely, T., Bull, F., Talbot, D., Sattar, N. Khunti, K. (2008) Walking and inflammatory markers in individuals screened for type 2 diabetes. Preventive Medicine July 3. [Epub ahead of print].
39. Zhong, Y., Slade, G. D., Beck, J. D. Offenbacher, S. (2007) Gingival crevicular fluid interleukin-1beta, prostaglandin E2 and periodontal status in a community population. Journal of Clinical Periodontology 34, 285 293.