Impaired transient receptor potential vanilloid 1 in streptozotocin-induced diabetic hearts

International Journal of Cardiology

Volumn 134, Issue 2, 2009, Pages 290-292

  Song, Jun Xian ^a   Wang, Li Hong ^a   Yao, Lei ^a   Xu, Chao ^b   Wei, Zhong Hai ^a   Zheng, Liang Rong ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SHAOXING PEOPLE S HOSPITAL   (China)

Author keywords

Calcitonin gene related peptide; Diabetic neuropathy; Substance P; Transient receptor potential vanilloid 1

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GLUCOSE; MESSENGER RNA; STREPTOZOCIN; SUBSTANCE P; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; HEART NERVE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; HEART DISEASES; MICE; MICE, INBRED C57BL; TRPV CATION CHANNELS;

EID: 64849115108     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.12.081     Document Type: Article

References (8)

1. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
2. Zahner M.R., Li D.P., Chen S.R., and Pan H.L. Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol 551 (2003) 515-523
3. Wang L.H., and Wang D.H. TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice. Circulation 112 (2005) 3617-3623
4. -ΔΔCT method. Methods 25 (2001) 402-408
5. + sensory neurons control b cell stress and islet inflammation in autoimmune diabetes. Cell 127 (2006) 1123-1135
6. Ieda M., Kanazawa H., Ieda Y., et al. Nerve growth factor is critical for cardiac sensory innervation and rescues neuropathy in diabetic hearts. Circulation 114 (2006) 2351-2363
7. Cameron N.E., Eaton S.E.M., Cotter M.A., and Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 44 (2001) 1973-1988
8. Pan H.L., and Chen S.R. Sensing tissue ischemia: another new function for capsaicin receptor?. Circulation 110 (2004) 1826-1831