Degeneration of cholinergic rat basal forebrain neurons after experimental subarachnoid hemorrhage

Neurosurgery

Volumn 63, Issue 2, 2008, Pages 336-344

  Löhr, Mario ^a,c   Tzouras, Georgios ^a   Molcanyi, Marek ^a   Ernestus, Ralf Ingo ^a   Hampl, Jürgen A ^a   Fischer, Jürgen H ^a   Sahin, Kurtulus ^a   Arendt, Thomas ^b   Härtig, Wolfgang ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

Basal forebrain; Cholinergic degeneration; Hypoxia; Neuropsychological deficits; Subarachnoid hemorrhage

Indexed keywords

4 AMINOBUTYRIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD AUTOTRANSFUSION; BRAIN PERFUSION; BRAIN TISSUE; CELL COUNT; CELL LOSS; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DENSITOMETRY; FOREBRAIN; HIPPOCAMPUS; HYPOXEMIA; INTRACRANIAL PRESSURE; MALE; NEOCORTEX; NERVE DEGENERATION; NONHUMAN; OXYGEN TISSUE LEVEL; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; STEREOTACTIC PROCEDURE; SUBARACHNOID HEMORRHAGE; WISTAR RAT; ANIMAL; CHOLINERGIC NERVE; COMPARATIVE STUDY; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; CHOLINERGIC FIBERS; MALE; NERVE DEGENERATION; NEURONS; PROSENCEPHALON; RATS; RATS, WISTAR; SUBARACHNOID HEMORRHAGE;

EID: 64849099069     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000320422.54985.6D     Document Type: Article

References (53)

1. Albert MS: Cognitive and neurobiologc markers of early Alzheimer disease. Proc Natl Acad Sci U S A 93:13547-13551, 1996.
2. Arendt T, Bigl V, Arendt A, Tennstedt A: Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease. Acta Neuropathol 61:101-108, 1983.
3. Bartus RT, Dean RL 3rd, Beer B, Lippa AS: The cholinergic hypothesis of geriatric memory dysfunction. Science 217:408-414, 1982.
4. Beach TG, Kuo YM, Spiegel K, Emmerling MR, Sue LI, Kokjohn K, Roher AE: The cholinergic deficit coincides with Abeta deposition at the earliest histopathologic stages of Alzheimer disease. J Neuropathol Exp Neurol 59:308-313, 2000.
5. Bierer LM, Haroutunian V, Gabriel S, Knott PJ, Carlin LS, Purohit DP, Perl DP, Schmeidler J, Kanof P, Davis KL: Neurochemical correlates of dementia severity in Alzheimer's disease: Relative importance of cholinergic deficits. J Neurochem 64:749-760, 1995.
6. Bigl V, Arendt T, Biesold D: The nucleus basalis of Meynert during ageing and in dementing disorders, in Steriade M, Biesold D (eds): Brain Cholinergic Systems. Oxford, Oxford University Press, 1990, pp 364-386.
7. Böttger S, Prosiegel M, Steiger HJ, Yassouridis A: Neurobehavioral disturbances, rehabilitation outcome, and lesion site in patients after rupture and repair of anterior communicating artery aneurysm. J Neurol Neurosurg Psychiatry 65:93-102, 1998.
8. Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M: Patterns of cognitive decline in presymptomatic Alzheimer disease: A prospective community study. Arch Gen Psychiatry 58:853-858, 2001.
9. Coyle JT, Price DL, DeLong MR: Alzheimer's disease: A disorder of cortical cholinergic innervation. Science 219:1184-1190, 1983.
10. Critchley GR, Bell BA: Acute cerebral tissue oxygenation changes following experimental subarachnoid hemorrhage. Neurol Res 25:451-456, 2003.
11. Freund TF: GABAergic septohippocampal neurons contain parvalbumin. Brain Res 478:375-381, 1989.
12. Freund TF, Antal M: GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus. Nature 336:170-173, 1988.
13. Gaetani P, Tartara F, Pignatti P, Tancioni F, Rodriguez y Baena R, De Benedetti F: Cisternal CSF levels of cytokines after subarachnoid hemorrhage. Neurol Res 20:337-342, 1998.
14. Hammes EM: Reaction of the meninges to blood. Arch Neurol Psychiatr 52:505-514, 1944.
15. 2+ antagonist nimodipine. Neuroscience 101:101-114, 2000.
16. Härtig W, Bauer A, Brauer K, Grosche J, Hortobágyi T, Penke B, Schliebs R, Harkany T: Functional recovery of cholinergic basal forebrain neurons under disease conditions: Old problems, new solutions? Rev Neurosci 13:95-165, 2002.
17. Härtig W, Brückner G, Holzer M, Brauer K, Bigl V: Digoxigenylated primary antibodies for sensitive dual-peroxidase labelling of neural markers. Histochem Cell Biol 104:467-472, 1995.
18. Hoffman WE, Wheeler P, Edelman G, Charbel FT, Torres NJ, Ausman JI: Hypoxic brain tissue following subarachnoid hemorrhage. Anesthesiology 92:442-46, 2000.
19. Horvath KM, Hårtig W, Van der Veen R, Keijser JN, Mulder J, Ziegert M, Van der Zee EA, Harkany T, Luiten PG: 17fl-estradiol enhances cortical cholinergic innervation and preserves synaptic density following exritotoxic lesions to the rat nucleus basalis magnocellularis. Neuroscience 110:489-504, 2002.
20. Hütter BO, Gilsbach JM: Which neuropsychological deficits are hidden behind a good outcome (Glasgow = I) after aneurysmal subarachnoid hemorrhage? Neurosurgery 33:999-1006, 1993.
21. Hütter BO, Kreitschmann-Andermahr I, Gilsbach JM: Health-related quality of life after aneurysmal subarachnoid hemorrhage: Impacts of bleeding severity, computerized tomography findings, surgery, vasospasm, and neurological grade. J Neurosurg 94:241-251, 2001.
22. Jackowski A, Crockard A, Burnstock G, Russell RR, Kristek F: The time course of intracranial pathophysiological changes following experimental subarachnoid haemorrhage in the rat. J Cereb Blood Flow Metab 10:835-849, 1990.
23. Jaeger M, Soehle M, Schuhmann MU, Winkler D, Meixensberger J: Correlation of continuously monitored regional cerebral blood flow and brain tissue oxygen. Acta Neurochir (Wien) 147:51-56, 2005.
24. Katchanov J, Waeber C, Gertz K, Gietz A, Winter B, Brück W, Dirnagl W, Veh RW, Endres M: Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain Pathol 13:452-464, 2003.
25. Kawamata T, Takeshita M, Ujiie H, Sato K, Izawa M, Kagawa M, Takakura K: Acetylcholine determination of cerebrospinal fluid in aneurysmal subarachnoid hemorrhage. Surg Neurol 41:399-404, 1994.
26. Larsson E, Lindvall O, Kokaia Z: Stereological assessment of vulnerability of immunocytochemically identified striatal and hippocampal neurons after global cerebral ischemia in rats. Brain Res 913:117-132, 2001.
27. Leifer D, Kowall NW: Immunohistochemical patterns of selective cellular vulnerability in human cerebral ischemia. J Neurol Sci 119:217-228, 1993.
28. Ljunggren B, Sonesson B, Säveland H, Brandt L: Cognitive impairment and adjustment in patients with neurological deficits after aneurysmal SAH and early operation. J Neurosurg 62:673-679, 1985.
29. Matz PG, Fujimura M, Chan PH: Subarachnoid hemolysate produces DNA fragmentation in a pattern similar to apoptosis in mouse brain. Brain Res 858:312-319, 2000.
30. Matz PG, Sundaresan S, Sharp FR, Weinstein PR: Induction of HSP70 in rat brain following subarachnoid hemorrhage produced by endovascular perforation. J Neurosurg 85:138-145, 1996.
31. Mesulam MM, Mufson EJ, Levey AI, Wainer BH: Cholinergic innervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey. J Comp Neurol 214:170-197, 1983.
32. Nau R, Haase S, Bunkowski S, Brück W: Neuronal apoptosis in the dentate gyrus in humans with subarachnoid hemorrhage and cerebral hypoxia. Brain Pathol 12:329-336, 2002.
33. Ogden JA, Mee EW, Henning M: A prospective study of impairment of cognition and memory recovery after subarachnoid hemorrhage. Neurosurgery 33:572-587, 1993.
34. Ostrowski RP, Colohan AR, Zhang JH: Molecular mechanisms of early brain injury after subarachnoid hemorrhage. Neurol Res 28:399-414, 2006.
35. Paxinos G, Watson C: The Rat Brain in Stereotaxic Coordinates. Amsterdam, Elsevier Academic Press, 2005.
36. Perry E, Walker M, Grace J, Perry R: Acetylcholine in mind: A neurotransmitter correlate of consciousness? Trends Neurosci 22:273-280, 1999.
37. Prunell GF, Mathiesen T, Diemer NH, Svendgaard NA: Experimental subarachnoid hemorrhage: Subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models. Neurosurgery 52:165-176, 2003.
38. Prunell GF, Mathiesen T, Svendgaard NA: A new experimental model in rats of the pathophysiology of subarachnoid hemorrhage. Neuroreport 13:2553-2556, 2002.
39. Prunell GF, Svendgaard NA, Alkass K, Mathiesen T: Delayed cell death related to acute cerebral blood flow changes following subarachnoid hemorrhage in the rat brain. J Neurosurg 102:1046-1054, 2005.
40. Prunell GF, Svendgaard NA, Alkass K, Mathiesen T: Inflammation in the brain after experimental subarachnoid hemorrhage. Neurosurgery 56:1082-1092, 2005.
41. Sarter M, Bruno JP: Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: Differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents. Neuroscience 95:933-952, 2000.
42. Sarter M, Bruno JP: The neglected constituent of the basal forebrain corti-copetal projection system: GABAergic projections. Eur J Neurosci 15:1867-1873, 2002.
43. Schliebs R, Arendt T: The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. J Neural Transm 113:1625-1644, 2006.
44. Sehba FA, Bederson JB: Mechanisms of acute brain injury after subarachnoid hemorrhage. Neurol Res 28:381-398, 2006.
45. Semba K: Multiple output pathways of the basal forebrain: Organization, chemical heterogeneity, and roles in vigilance. Behav Brain Res 115:117-141, 2000.
46. Szutowicz A, Bielarczyk H, Gul S, Ronowska A, Pawelczyk T, Jankowska-Kulawy A: Phenotype-dependent susceptibility of cholinergic neuroblastoma cells to neurotoxic inputs. Metab Brain Dis 21:149-161, 2006.
47. Szutowicz A, Tomaszewicz M, Jankowska A, Madziar B, Bielarczyk H: Acetyl-CoA metabolism in cholinergic neurons and their susceptibility to neurotoxic inputs. Metab Brain Dis 15:29-4, 2000.
48. Takizawa T, Tada T, Kitazawa K, Tanaka Y, Hongo K, Kameko M, Uemura KI: Inflammatory cytokine cascade released by leucocytes in cerebrospinal fluid after subarachnoid hemorrhage. Neurol Res 23:724-730, 2001.
49. Terry AV Jr, Buccafusco JJ: The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: Recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 306:821-827, 2003.
50. Tucek S: Short-term control of the synthesis of acetylcholine. Prog Biophys Mol Biol 60:59-69, 1993.
51. Varga C, Härtig W, Grosche J, Keijser J, Luiten PG, Seeger J, Brauer K, Harkany T: Rabbit forebrain cholinergic system: Morphological characterization of nuclei and distribution of cholinergic terminals in the cerebral cortex and hippocampus. J Comp Neurol 460:597-611, 2003.
52. West MJ: New stereological methods for counting neurons. Neurobiol Aging 14:275-285, 1993.
53. Wurtman RJ: Choline metabolism as a basis for the selective vulnerability of cholinergic neurons. Trends Neurosci 15:117-122, 1992.