M22 based (manual) ELISA for TSH-receptor antibody (TRAb) measurement is more sensitive than 2nd generation TRAb assays

Clinica Chimica Acta

Volumn 403, Issue 1-2, 2009, Pages 266-

  Zöphel, Klaus ^a   Wunderlich, Gerd ^a   Kotzerke, Jörg ^a   von Landenberg, Philipp ^b   Roggenbuck, Dirk ^c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c GenExpress GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN RECEPTOR ANTIBODY;

CLINICAL PRACTICE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOASSAY; INTERMETHOD COMPARISON; LABORATORY TEST; LETTER; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULINS, THYROID-STIMULATING; SENSITIVITY AND SPECIFICITY;

EID: 64849098628     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.01.022     Document Type: Letter

References (5)

1. Hermsen D., Broecker-Preuss M., Casati M., et al. Technical evaluation of the first fully automated assay for the detection TSH receptor autoantibodies. Clin Chim Acta (2008) 10.1016/j.cca.2008.11.025
2. Liu C., Hermsen D., Dornberg J., et al. Comparison of M22-based ELISA and human-TSH-receptor-based luminescence assay for the measurement of thyrotropin receptor antibodies in patients with thyroid diseases. Horm Metab Res 40 (2008) 479-483
3. Rees Smith B., Bolton J., Young S., et al. A new assay for thyrotropin receptor autoantibodies. Thyroid 14 (2004) 830-835
4. Ekins R., and Edwards P. On the meaning of sensitivity. Clin Chem 43 (1997) 1824-1831
5. Jensen E., Petersen P.H., Blaabjerg O., Hansen P.S., and Hegedüs L. Improved sensitivity of a thyrotropin receptor antibody assay. Clin Chem 51 (2005) 2186-2187