A new assay for thyrotropin receptor autoantibodies

Thyroid

Volumn 14, Issue 10, 2004, Pages 830-835

  Smith, Bernard Rees ^a,b   Bolton, Jane ^a,b   Young, Stuart ^a,b   Collyer, Alastair ^a,b   Weeden, Alison ^a,b   Bradbury, Janet ^a,b   Weightman, David ^c   Perros, Petros ^c   Sanders, Jane ^a   Furmaniak, Jadwiga ^a  

^a RSR LTD   (United Kingdom)

^b FIRS Laboratories   (United Kingdom)

^c FREEMAN HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BIOTIN; HUMAN MONOCLONAL ANTIBODY; PEROXIDASE; STREPTAVIDIN; THYROTROPIN RECEPTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GRAVES DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; THYROTROPIN BLOOD LEVEL;

EID: 8444252110     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/1050725042451248     Document Type: Article

References (16)

1. Rees Smith B, McLachlan SM, Furmaniak J 1988 Autoantibodies to the thyrotropin receptor. Endocr Rev 9:106-121.
2. 125I-labelled TSH Receptor. J Clin Endocrinol Metab 84:3797-3802.
3. Bolton J, Sanders J, Oda Y, Chapman C, Konno R, Furmaniak J, Rees Smith B 1999 Measurement of thyroid-stimulating hormone receptor autoantibodies by ELISA. Clin Chem 45:2285-2287.
4. Costagliola S, Morgenthaler NG, Hoermann R, Badenhoop K, Struck J, Freitag D, Poertl S, Weglöhner W, Hollidt JM, Quadbeck B, Dumont JE, Schumm-Draeger P-M, Bergmann A, Mann K, Vassart G, Usadel K-H 1999 Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease. J Clin Endocrinol Metab 84:90-97.
5. Sanders J, Jeffreys J, Depraetere H, Richards T, Evans M, Kiddie A, Brereton K, Groenen M, Oda Y, Furmaniak J, Rees Smith B 2002 Thyroid-stimulating monoclonal antibodies. Thyroid 12:1043-1050.
6. Sanders J, Evans M, Premawardhana LDKE, Depraetere H, Jeffreys J, Richards T, Furmaniak J, Rees Smith B 2003 Human monoclonal thyroid stimulating autoantibody. Lancet 362:126-127.
7. Southgate K, Creagh FM, Teece M, Kingswood C, Rees Smith B 1984 A receptor assay for the measurement of TSH receptor antibodies in unextracted serum. Clin Endocrinol 20:539-543.
8. Beever K, Bradbury J, Phillips D, McLachlan SM, Pegg C, Goral A, Overbeck W, Feifel G, Rees Smith B 1989 Highly sensitive assays of autoantibodies to thyroglobulin and to thyroid peroxidase. Clin Chem 35:1949-1954.
9. Zweig MH, Campbell G 1993 Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 39:561-577.
10. Smith BR 1971 Characterisation of long-acting thyroid stimulator γG binding protein. Biochim Biophys Acta 229:649-662.
11. 125I-labeled receptor-purified Graves' immunoglobulins: Properties of their binding to human thyroid membranes. J Clin Endocrinol Metab 55:566-576.
12. Latrofa F, Chazenbalk GD, Pichurin P, Chen C-R, McLachlan SM, Rapoport B 2003 Characterisation of TSH receptor autoantibodies affinity-enriched to near purity from the serum of Graves' patients [ATA abstract no. 197]. Thyroid 13:734.
13. Morgenthaler NG, Minich WB, Willnich M, Bogusch T, Hollidt JM, Weglöhner W, Lenzner C, Bergmann A 2003 Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum. Mol Cell Endocrinol 212: 73-79.
14. Akamizu A, Kohn LD, Hiratani H, Saijo M, Tahara K, Nakao K 2000 Hashimoto's thyroiditis with heterogeneous antithyrotropin receptor antibodies: Unique epitopes may contribute to the regulation of thyroid function by the antibodies. J Clin Endocrinol Metab 85:2116-2121.
15. Kung AWC, Lau KS, Kohn LD 2001 Epitope mapping of TSH receptor-blocking antibodies in Graves' disease that appear during pregnancy. J Clin Endocrinol Metab 86:3647-3653.
16. Chazenbalk GD, Pichurin P, Chen C-R, Latrofa F, Johnstone AP, McLachlan SM, Rapoport B 2002 Thyroid-stimulating autoantibodies in Graves' disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor. J Clin Invest 110:209-217.