Significance of the cyclic structure and of arginine residues for the antibacterial activity of arenicin-1 and its interaction with phospholipid and lipopolysaccharide model membranes

Biological Chemistry

Volumn 390, Issue 4, 2009, Pages 337-349

  Andrä, Jörg ^a   Hammer, Malte U ^a   Grötzinger, Joachim ^b   Jakovkin, Igor ^b,c   Lindner, Buko ^a   Vollmer, Ekkehard ^a   Fedders, Henning ^b   Leippe, Matthias ^b   Gutsmann, Thomas ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Antimicrobial peptide; Arenicola marina; Endotoxin; Epithelia; Host defense peptide; Planar lipid bilayer

Indexed keywords

ARENICIN 1; ARGININE; CYCLOPEPTIDE; CYSTEINE; LIPOPOLYSACCHARIDE; LYSINE; PHOSPHOLIPID; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; SERINE; SODIUM CHLORIDE; TRYPSIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARENICOLA MARINA; ARTICLE; DISULFIDE BOND; HEMOLYSIS; PEPTIDE SYNTHESIS; POLYCHAETA; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTEUS MIRABILIS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ARGININE; CIRCULAR DICHROISM; DRUG DESIGN; ESCHERICHIA COLI; HUMANS; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; PEPTIDES; PEPTIDES, CYCLIC; PHOSPHOLIPIDS; PROTEUS MIRABILIS;

ARENICOLA MARINA; BACTERIA (MICROORGANISMS); PROTEUS MIRABILIS;

EID: 64849097942     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2009.039     Document Type: Article

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