Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: Role of α7 nicotinic receptors

European Journal of Pharmacology

Volumn 609, Issue 1-3, 2009, Pages 74-77

  Cui, Ranji ^a   Suemaru, Katsuya ^a   Li, Bingjin ^a   Kohnomi, Shuntaro ^a   Araki, Hiroaki ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

7 nicotinic receptor; 5 HT3 receptor; Place aversion; Tropisetron

Indexed keywords

BUNGAROTOXIN RECEPTOR; MECAMYLAMINE; METHYLLYCACONITINE; MORPHINE; NALOXONE; ONDANSETRON; TROPISETRON;

ANIMAL EXPERIMENT; ARTICLE; AVERSION; CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION;

ACONITINE; ANIMALS; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; MALE; MECAMYLAMINE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; ONDANSETRON; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SEROTONIN ANTAGONISTS;

EID: 64549164058     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.12.051     Document Type: Article

References (32)

1. Acquas E., and Di Chiara G. Depression of mesolimbic dopamine transmission and sensitization to morphine during opiate abstinence. J. Neurochem. 58 (1992) 1620-1625
2. Araki H., Kawakami K.Y., Jin C., Suemaru K., Kitamura Y., Nagata M., Futagami K., Shibata K., Kawasaki H., and Gomita Y. Nicotine attenuates place aversion induced by naloxone in single-dose, morphine-treated rats. Psychopharmacology 171 (2004) 398-404
3. Bickel W.K., Stitzer M.L., Liebson I.A., and Bigelow G.E. Acute physical dependence in man: effects of naloxone after brief morphine exposure. J. Pharmacol. Exp. Ther. 244 (1988) 126-132
4. 3 receptor antagonists block morphine- and nicotine-induced place-preference conditioning. Eur. J. Pharmacol. 151 (1988) 159-160
5. Funada M., and Shippenberg T.S. Differential involvement of D1 and D2 dopamine receptors in the expression of morphine withdrawal signs in rats. Behav. Pharmacol. 7 (1996) 448-453
6. Hashimoto K., Iyo M., Freedman R., and Stevens K.E. Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors. Psychopharmacology (Berl) 183 (2005) 13-19
7. Hashimoto K., Fujita Y., Ishima T., Hagiwara H., and Iyo M. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: role of α7 nicotinic receptors. Eur. J. Pharmacol. 553 (2006) 191-195
8. 3 receptor antagonists on behavioural measures of naloxone-precipitated opioid withdrawal. Psychopharmacology 105 (1991) 322-328
9. Hogg R.C., and Bertrand D. Partial agonists as therapeutic agents at neuronal nicotinic acetylcholine receptors. Biochem. Pharmacol. 73 (2007) 459-468
10. 3 antagonists reduce morphine self-administration in rats. Br. J. Pharmacol. 110 (1993) 1341-1346
11. Jin C., Araki H., Nagata M., Suemaru K., Shibata K., Kawasaki H., Hamamura T., and Gomita Y. Withdrawal-induced c-Fos expression in the rat centromedial amygdala 24 h following a single morphine exposure. Psychopharmacology 175 (2004) 428-435
12. Jin C., Araki H., Nagata M., Shimosaka R., Shibata K., Suemaru K., Kawasaki H., and Gomita Y. Expression of c-Fos in the rat central amygdala accompanies the acquisition but not expression of conditioned place aversion induced by withdrawal from acute morphine dependence. Behav. Brain Res. 161 (2005) 107-112
13. Klink R., de Kerchove d'Exaerde A., Zoli M., and Changeux J.P. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J. Neurosci. 21 (2001) 1452-1463
14. Koike K., Hashimoto K., Takai N., Shimizu E., Komatsu N., Watanabe H., Nakazato M., Okamura N., Stevens K.E., Freedman R., and Iyo M. Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophr. Res. 76 (2005) 67-72
15. 3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. Bioorg. Med. Chem. Lett. 11 (2001) 319-321
16. 3 receptor, a serotonin-gated ion channel. Science 254 (1991) 432-437
17. Martin W.R., and Eades C.G. A comparison between acute and chronic physical dependence in the chronic spinal dog. J. Pharmacol. Exp. Ther. 146 (1964) 385-394
18. McDonald R.V., Parker L.A., and Siegel S. Conditioned sucrose aversions produced by naloxone-precipitated withdrawal from acutely administered morphine. Pharmacol Biochem Behav. 58 (1997) 1003-1008
19. Motoshima S., Suemaru K., Kawasaki Y., Jin C., Kawasaki H., Gomita Y., and Araki H. Effects of α4β2 and α7 nicotinic acetylcholine receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats. Eur. J. Pharmacol. 519 (2005) 91-95
20. Narita M., Funada M., and Suzuki T. Regulations of opioid dependence by opioid receptor types. Pharmacol. Ther. 89 (2001) 1-15
21. Nomikos G.G., Hildebrand B.E., Panagis G., and Svensson T.H. Nicotine withdrawal in the rat: role of alpha7 nicotinic receptors in the ventral tegmental area. Neuroreport 10 (1999) 697-702
22. Parker L.A., and Joshi A. Naloxone-precipitated morphine withdrawal induced place aversions: effect of naloxone at 24 h postmorphine. Pharmacol. Biochem. Behav. 61 (1998) 331-333
23. Parker L.A., Cyr J.A., Santi A.N., and Burton P.D. The aversive properties of acute morphine dependence persist 48 h after a single exposure to morphine evaluation by taste and place conditioning. Pharmacol. Biochem. Behav. 72 (2002) 87-92
24. Pei Q., Zetterström T., Leslie R.A., and Grahame-Smith D.G. 5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat. Eur J Pharmacol. 230 (1993) 63-68
25. Pothos E., Rada P., Mark G.P., and Hoebel B.G. Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain Res. 566 (1991) 348-350
26. Rossetti Z.L., Hmaidan Y., and Gessa G.L. Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats. Eur. J. Pharmacol. 221 (1992) 227-234
27. Schilström B., Svensson H.M., Svensson T.H., and Nomikos G.G. Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of α7 nicotinic receptors in the ventral tegmental area. Neuroscience 85 (1998) 1005-1009
28. Schulteis G., Heyser C.J., and Koob G.F. Opiate withdrawal signs precipitated by naloxone following a single exposure to morphine: potentiation with a second morphine exposure. Psychopharmacology (Berl). 129 (1997) 56-65
29. Schulteis G., Heyser C.J., and Koob G.F. Differential expression of response-disruptive and somatic indices of opiate withdrawal during the initiation and development of opiate dependence. Behav. Pharmacol. 10 (1999) 235-242
30. Simpson K., Spencer C.M., and McClellan K.J. Tropisetron: an update of its use in the prevention of chemotherapy-induced nausea and vomiting. Drugs 59 (2000) 1297-1315
31. Suzuki T., Ise Y., Mori T., and Misawa M. Attenuation of mecamylamine-precipitated nicotine-withdrawal aversion by the 5-HT3 receptor antagonist ondansetron. Life Sci. 61 (1997) 249-254
32. 3 receptor antagonist ondansetron on the ketamine- and dizocilpine-induced place preferences in mice. Eur. J. Pharmacol. 385 (1999) 99-102