Naloxone-precipitated morphine withdrawal induced place aversions: Effect of naloxone at 24 hours postmorphine

Pharmacology Biochemistry and Behavior

Volumn 61, Issue 3, 1998, Pages 331-333

  Parker, Linda A ^a   Joshi, Anish ^a  

^a WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

Acute dependence; Learning; Morphine; Naloxone; Place aversion; Place conditioning; Precipitated withdrawal; Rat; Withdrawal

Indexed keywords

MORPHINE; NALOXONE;

ANIMAL EXPERIMENT; ARTICLE; AVERSION; CONDITIONING; CONTROLLED STUDY; LEARNING; MALE; NONHUMAN; OPIATE ADDICTION; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; WITHDRAWAL SYNDROME;

ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; MALE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME; TASTE;

EID: 0031768787     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00104-X     Document Type: Article

References (20)

1. Baldwin, H. A.; Koob, G. F.: Rapid induction of conditioned opiate withdrawal in the rat. Neuropsychopharmacology 8:15-21; 1993.
2. Eisenberg, R. M.: Further studies on the acute dependence produced by morphine in opiate naive rats. Life. Sci. 31:1531-1540; 1982.
3. Gellert, V. F.; Sparber, S. B.: A comparison of the effects of naloxone upon body weight loss and suppression of fixed-ratio operant behavior in morphine dependent rats. J. Pharmacol. Exp Ther. 201:44-54; 1977.
4. Heishman, S. J.; Stitzer, M. L.; Bigelow, G. E.; Liebson, I. A.: Acute opioid physical dependence in humans: Effects of naloxone at 6 and 24 hours postmorphine. Pharmacol. Biochem. Behav. 36:393-399; 1990.
5. Huidobro, F.: Some relations between tolerance and physical dependence to morphine in mice. Eur J. Pharmacol. 15:79-84; 1971.
6. Jacob, J. J.; Michaud, G. M.: Aucte physical dependence in the waking dog after a single low dose of morphine. Psychol. Med. 4:270-273; 1974.
7. Jaffe, J. H.; Martin, W. R.: Opioid analgesics and antagonists. In: Gilman, A. G.; Rall, T. W.; Nies, A. S.; Taylor, P., eds. The pharmacological basis of therapeutics 8th ed. New York: Pergamon; 1990:485-521.
8. June, H. L.; Stitzer, M. L.; Cone, E. C.: Acute physical dependence: Time course and relation to human plasma morphine concentrations. Clin. Pharmacol. Ther. 57:270-280; 1995.
9. Krystal, J. H.; Redmond, D. E.: A preliminary description of acute physical dependence on morphine in the vervet monkey. Pharmacol. Biochem. Behav. 18:289-291; 1983.
10. Martin, W. R.; Eades, C. G.: A comparison between acute and chronic physical dependence in the chronic spinal dog. J. Pharmacol. Exp. Ther. 146:385-394; 1977.
11. McDonald, R. V.; Parker, L. A.; Siegel, S.: Conditioned sucrose aversions produced by naloxone-precipitated withdrawal from acutely administered morphine. Pharmacol. Biochem. Behav. 58:1-6; 1997.
12. Meyer, D. R.; Sparber, S. B.: Evidence of possible opiate dependence during the behavioral depressant action of a single dose of morphine. Life Sci. 21:1087-1094; 1977.
13. Mucha, R. F.: Opiate withdrawal-produced dysphoria: A taste preference conditioning model. In: Bolton, A. A.; Baker, G. B.; Wu, P. H., eds. Animal models of drug addiction. Totowa, NJ: Humana Press; 1992:271-315.
14. Mucha, R. F.; Herz, A.: Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning. Psychopharmacology (Berlin) 86:274-280; 1985.
15. Mucha, R. F.; Iversen, B. D.: Reinforcing properties of morphine and naloxone revealed by conditional place preference: A proceudral examination. Psychopharmacology (Berlin) 82:241-247; 1984.
16. Mucha, R. F.; Gritti, M. D.; Kim, C.: Aversive properties of opiate withdrawal in rats. NIDA Res. Monogr. 75:567-570; 1986.
17. Parker, L. A.; Rennie, M.: Naltrexone-induced aversions: Assessment by place conditioning, taste reactivity and taste avoidance paradigms. Pharmacol. Biochem. Behav. 41:559-565; 1992.
18. Schulteis, G.; Koob, G. F.: Reinforcement processes in opiate addiction: A homeostatic model. Neurochem. Res. 21:1437-1454; 1996.
19. Wei, E. T.; Loh, H. H.: Physical dependence on opiate-like peptides. Science 193:1262-1263; 1976.
20. Wiley, J. N.; Downs, D. A.: Naloxone-precipitated jumping in mice pretreated with acute injections of opioids. Life Sci. 25:797-801; 1979.