Full-length article Acute pulmonary infammation is inhibited in CXCR3 knockout mice after short-term cigarette smoke exposure

Acta Pharmacologica Sinica

Volumn 29, Issue 12, 2008, Pages 1432-1439

  Nie, Li ^a,b   Xiang, Ruo Lan ^c   Liu, Yong ^b   Zhou, Wei Xun ^b   Jiang, Lei ^b   Lu, Bao ^d   Pang, Bao Sen ^e   Cheng, De Yun ^a   Gao, Jin Ming ^b  

^a SICHUAN UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d HARVARD MEDICAL SCHOOL   (United States)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

CD8; Cigarette smoke; CXCL10; CXCR3

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CIGARETTE SMOKE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; CHEMOKINE; CXCR3 PROTEIN, MOUSE; CYTOKINE;

AIRWAY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENVIRONMENTAL EXPOSURE; GENE; INFLAMMATORY CELL; KNOCKOUT MOUSE; LOBAR PNEUMONIA; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE; ANIMAL; CYTOLOGY; DRUG EFFECT; GENETICS; HUMAN; IMMUNOLOGY; LUNG; METABOLISM; MOUSE MUTANT; PATHOLOGY; PNEUMONIA; SMOKE; SMOKING; TOBACCO;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CD8-POSITIVE T-LYMPHOCYTES; CHEMOKINE CXCL10; CHEMOKINES; CYTOKINES; HUMANS; LUNG; MICE; MICE, KNOCKOUT; PNEUMONIA; RECEPTORS, CXCR3; SMOKE; SMOKING; TOBACCO;

EID: 64549157662     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00899.x     Document Type: Article

References (21)

1. Pauwels RA, Rabe KF. Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet 2004; 364: 613-20.
2. Chung KF. The role of airway smooth muscle in the pathogenesis of airway wall remodeling in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005; 2: 347-54.
3. + T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998; 157: 822-6.
4. Saetta M, Mariani M, Panina-Bordignon P, Turato G, Buonsanti C, Baraldo S, et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002; 165: 1404-9.
5. Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, et al. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PloS Med 2004; 1: e8.
6. Hancock WW, Lu B, Gao W, Csizmadia V, Faia K, King JA, et al. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med 2000; 192: 1515-20.
7. D'hulst AI, Vermaelen K Y, Brusselle GG, Joos GF, Pauwels RA. Time course of cigarette smoke-induced pulmonary infammation in mice. Eur Respir J 2005; 26: 204-13.
8. Kubo S, Kobayashi M, Masunaga Y, Ishii H, Hirano Y, Takahashi K, et al. Cytokine and chemokine expression in cigarette smoke-induced lung injury in guinea pigs. Eur Respir J 2005; 26: 993-1001.
9. Thatcher TH, McHugh NA, Egan RW, Chapman RW, Hey JA, Turner CK, et al. Role CXCR2 in cigarette smoke-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol 2005; 289: L322-8.
10. D'Ambrosio D, Mariani M, Panina-Bordignon P, Sinigaglia F. Chemokines and their receptors guiding T lymphocyte recruitment in lung infammation. Am J Respir Crit Care Med 2001; 164: 1266-75.
11. Barczyk A, Pierzchala W, Kon OM, Cosio B, Adcock IM, Barnes PJ. Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease. J Allergy Clin Immunol 2006; 117: 1484-92.
12. Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD. CD8+ T cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 2007; 178: 8090-6.
13. Richman-Eisenstat JB, Jorens PG, Hébert CA, Ueki I, Nadel JA. Interleukin-8: an important chemoattractant in sputum of patients with chronic infammatory airway diseases. Am J Physiol 1993; 264: L413-8.
14. Wang Z, Zheng T, Zhu Z, Homer RJ, Riese RJ, Chapman HA Jr, et al. Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med 2000; 192: 1587-600.
15. Churg A, Tai H, Coulthard T, Wang R, Wright JL. Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall. Am J Respir Crit Care Med 2006; 174:1327-34.
16. Ma B, Kang MJ, Lee CG, Chapoval S, Liu W, Chen Q, et al. Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema. J Clin Invest 2005; 115: 3460-72.
17. Bracke KR, D'hulst AI, Maes T, Demedts IK, Moerloose KB, Kuziel WA, et al. Cigarette smoke-induced pulmonary inflammation, but not airway modelling, is attenuated in chemokine receptor 5-defcient mice. Clin Exp Allergy 2007; 37: 1467-79.
18. Bracke KR, D'hulst AI, Maes T, Moerloose KB, Demedts IK, Lebecque S, et al. Cigarette smoke-induced pulmonary infammation and emphysema are attenuated in CCR6-defcienct mice. J Immunol 2006; 177: 4350-9.
19. Demedts IK, Bracke KR, Van Pottelberge G, Testelmans D, Verleden GM, Vermassen FE, et al. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 175: 988-1005.
20. Costa C, Rufno R, Traves SL, Lapa E, Silva JR, Bames PJ, et al. CXCR3 and CCR5 chemokines in induced sputum from patients with COPD. Chest 2008; 133: 26-33.
21. Barnes PJ, Cosio MG. Characterization of T lymphocytes in chronic obstructive pulmonary disease. PLoS Med 2004; 1: e20.