The presence of cholinomimetic and calcium channel antagonist constituents in Piper betle Linn.

Phytotherapy Research

Volumn 14, Issue 6, 2000, Pages 436-442

  Gilani, Anwar H ^a   Aziz, Nauman ^a   Khurram, Irfan M ^a   Rao, Zeeshan A ^a   Ali, Nadia K ^a  

^a AGA KHAN UNIVERSITY MEDICAL COLLEGE   (Pakistan)

Author keywords

Calcium channel antagonist; Cholinomimetic; Piper betle extract; Smooth muscle activity

Indexed keywords

ACETIC ACID ETHYL ESTER; ATROPINE; BETEL EXTRACT; CALCIUM CHANNEL BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; HEXAMETHONIUM; POTASSIUM; THIOPENTAL; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; GUINEA PIG; ILEUM; MUSCLE CONTRACTION; NONHUMAN; RABBIT; SMOOTH MUSCLE; SPASMOLYSIS;

ANIMALS; ARECA; CALCIUM CHANNEL BLOCKERS; CHOLINERGIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUINEA PIGS; ILEUM; JEJUNUM; MALE; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; RABBITS;

CAVIA PORCELLUS; ORYCTOLAGUS CUNICULUS; PIPER BETLE; SUS SCROFA;

EID: 0033822410     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1573(200009)14:6<436::AID-PTR620>3.0.CO;2-C     Document Type: Article

References (52)

1. Antifertility effect of Piper betle Linn. extract on ovary and testis of Albino rats
2. Calcium antagonists: Potential for asthma therapy
3. Protective effect of hydroxychavicol, a phenolic component of betle leaf, against the tobacco-specific carcinogens
4. Some quantitative uses of drug antagonists
5. Leaf oil of Piper betle. The in vitro antimicrobial studies
6. Studies on morphology and chemistry of Piper betle L.
7. Mechanism of action of transmitters and other substances on smooth muscles
8. Muscarinic receptor agonists and antagonists
9. Role of oxidative DNA damage in the mechanism of hydroxychavicol genotoxicity
10. The mutagenicity of nitrite-treated aqueous extract of Piper betle L.
11. C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle infloresence extract
12. Identification of fungicidal and nematocidal components in the leaves of Piper betle (Piperaceae)
13. ++ antagonists
14. ++ in myocardium, cardiac pacemakers and vascular smooth muscle
15. Biological activity of the essential oil of Piper betle L.
16. Volatile constituents of the essental oil of Pipe betle L. (Cultivar Sagar Bangal)
17. Presence of acetylcholine-like substance(s) in Sesamum indicum
18. Cardio-selectivity of himbacine: A muscarine receptor antagonist
19. Interaction of ebeinone, an alkaloid from Fritillaria imperialis, at two muscarinic acetylcholine receptor subtypes
20. ++ channel blocking activity of Artemisia scoparia extract
21. Cardiovascular action of Daucus carota
22. Interaction of ebeinone, an alkaloid from Fritillaria imperialis, at two muscarinic acetylcholine receptor subtypes
23. Calcium antagonism and calcium entry blockade
24. A comparative study of the essential oils of five Piper species from Peninsular Malaysia
25. Studies on promoting activity of Taiwan betel quid ingredients in hamster buccal pouch carcinogenesis
26. ++ channel antagonists
27. Role of oxidative DNA damage in hydroxychavicol-induced genotoxicity
28. A case-control study of oral cancer in Changhua County, Taiwan
29. Antifungal activity of leaf extracts of some higher plants
30. Mechanism mediating the vasorelaxing action of eugenol, a pungent oil, on rabbit arterial tissue
31. Betel: Consumption and consequences
32. Leaf oil of Piper betle Linn. The in vitro antimicrobial studies
33. Absorption and distribution
34. Antimotility effects of Piper betle leaf extract on washed human spermatozoa
35. Effect of chronic tobacco-betle-lime 'quid' chewing on human salivary secretions
36. Relaxant effects on tracheal and ileal smooth muscles of the guinea pig
37. Triterpenes and β-sitosterol from Piper betle: Isolation, antiplatelet and anti-inflammatory effects
38. Wound healing activity of Curcuma aromatica and Piper betle
39. Studies on essential oil of betle leaf (Piper betle L.) Part III vars. Desi Desawari and Mahoba Desawari
40. Studies on essential oil of betlevine leaf (Piper betle) Part II. Vars; Desi Bangla, Ramtek Bangla and Calcutta Bangla
41. Studies on effect of Psoralea corylifolia and Piper betle on cholinesterase and succinic dehydrogenase enzyme as possible targets of their anthelmintic action
42. Oral lesions, genotoxicity and nitrosamines in betel quid chewers with no obvious increase in oral cancer risk
43. Drugs affecting calcium-regulation and actions
44. Cumulative dose-response curves. II. Techniques for the making of dose-response curves in isolated organs and the evaluation of drug parameters
45. The separation of phenolics from Piper betle leaf and the effect on the mutagenicity of arecoline
46. Effect of betel quid on catecholamine secretion from adrenal chromaffin cells
47. Some new PAF antagonistic neolignans from Piper betle
48. Piperbetol, methylpiperbetol, piperol A and piperol B: A new series of highly specific PAF receptor antagonists from Piper betle