Effects of interferon-α on the inflammatory response of swine peripheral blood mononuclear cells

Journal of Interferon and Cytokine Research

Volumn 29, Issue 4, 2009, Pages 241-247

  Amadori, Massimo ^a   Farinacci, Maura ^b   Begni, Barbara ^a   Faita, Roberto ^a   Podavini, Damiano ^a   Colitti, Monica ^b  

^a ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

^b Faculty of Medicine   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PIGLET; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; WEANING; WEIGHT GAIN;

ANIMALS; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE;

SUIDAE;

EID: 64549152510     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2008.0074     Document Type: Article

References (34)

1. Alvarado J, Taylor P, Castillo JR, Thomas LE. 2005. Interferon gamma bound to extracellular matrix changes the hyporesponsiveness to LPS in crypt but not villous intestinal cells. Immunol Lett 99:109-112.
2. Alvarado J, del Castillo JR, Thomas LE. 2008. Modulation of membrane type 1 matrix metalloproteinase by LPS and gamma interferon bound to extracellular matrix in intestinal crypt cells. Cytokine 41:155-161.
3. Amadori M. 2007. The role of interferon-α as homeostatic agent in the infl ammatory response: a balance between danger and response? J Interferon Cytokine Res 27:181-189.
4. Artursson K, Wallgren P, Alm G. 1989. Appearance of interferon-α in serum and signs of reduced immune function in pigs after transport and installation in a fattening farm. Vet Immunol Immunopathol 23:345-353.
5. Asai T, Okada M, Ono M, Irisawa T, Mori Y, Yokomizo Y, Sato S. 1993. Increased levels of tumor necrosis factor and interleukin 1 in bronchoalveolar lavage fl uids from pigs infected with Mycoplasma hyopneumoniae. Vet Immunol Immunopathol 38:253-260.
6. Begni B, Amadori M, Ritelli M, Podavini D. 2005. Effects of interferon-α on the infl ammatory response of swine leukocytes to bacterial endotoxin. J Ifn Cyt Res 25:202-208.
7. Billiau A. 1988. Gamma-interferon: the match that lights the fi re? Immunol Today 9:37-40.
8. Bocci V, Paulesu L, Muscettola M, Viti, A. 1985. The physiologic interferon response. VI. Interferon activity in human plasma after a meal and drinking. Lymphokine Res 4:151-158.
9. Bocci V. 1990. Is interferon effective after oral administration? The state of the art. J Biol Regul Homeost Agents 4:81-83.
10. Bustin SA. 2000. Absolute quantifi cation of mRNA using realtime reverse transcription polymerase chain reaction assays. J Molecular Endocrinol 25:169-193.
11. Carstensen L, Røntved CM, Nielsen JP. 2005. Determination of tumor necrosis factor-alpha responsiveness in piglets around weaning using an ex vivo whole blood stimulation assay. Vet Immunol Immunopathol 105:59-66.
12. Chamorro S, Revilla C, Alvarez B, Alonso F, Ezquerra A, Domínguez J. 2005. Phenotypic and functional heterogeneity of porcine blood monocytes and its relation with maturation. Immunology 114:63-71.
13. Cummins JM, Krakowka GS, Thompson CG. 2005. Systemic effects of interferons after oral administration in animals and humans. Am J Vet Res 66:164-176.
14. Duvigneau JC, Hartl RT, Teinfalt M, Gemeiner M. 2003. Delay in processing whole blood affects cytokine expression. J Immunol Methods 272:11-21.
15. Harding JC, Baarsch MJ, Murtaugh MP. 1997. Association of tumor necrosis factor and acute phase reactant changes with post arrival disease in swine. Zentralbl Veterinärmed B 44:405-413. Ebdrup L, Krog J, Granfeldt A, Larsen PØ, Vestergaard C, Hokland M, Tønnesen E. 2008. Leukocyte, plasma, and organ-associated cytokine profi les in an animal model of acute infl ammation. APMIS 116:352-360.
16. Malmgaard L. 2004. Induction and regulation of IFNs during viral infections. J Interferon Cytokine Res 24:439-454.
17. Meager A. 1987. Quantifi cation of interferons by anti-viral assays and their standardization. In: Clemens MJ, Morris AG, Gearing AJH, eds. Lymphokines and interferons, a practical approach. Oxford: IRL Press Limited, pp 129-147.
18. Montagne L, Cavaney FS, Hampson DJ, Lallès JP, Pluske JR. 2004. Effect of diet composition on postweaning colibacillosis in piglets. J Anim Sci 82:2364-2374.
19. Moue M, Tohno M, Shimazu T, Kido T, Aso H, Saito T, Kitazawa H. 2008. Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line. Biochim Biophys Acta 1780:134-144.
20. Murphey ED, Traber DL. 2000. Pretreatment with tumor necrosis factor-alpha attenuates arterial hypotension and mortality induced by endotoxin in pigs. Crit Care Med 28:2015-2021.
21. Nuntaprasert A, Mori Y, Muneta Y, Yoshihara K, Tsukiyama-Kohara K, Kai C. 2005. The effect of recombinant swine interleukin-4 on swine immune cells and on pro-infl ammatory cytokine productions in pigs. Comp Immunol Microbiol Infect Dis 28:83-101.
22. Pfaffl MW. 2001. A new mathematical model for relative quantifi cation in real-time RT-PCR. Nucleic Acids Res 29:45.
23. Pié S, Lallès JP, Blazy F, Laffi tte J, Sève B, Oswald IP. 2004. Weaning is associated with an upregulation of expression of infl ammatory cytokines in the intestine of piglets. J Nutr 134:641-647.
24. Robinson TL, Sutherland IA, Sutherland J. 2007. Validation of candidate bovine reference genes for use with real-time PCR. Vet Immunol Immunopathol 115: 160-165.
25. Rozen S, Skaletsky HJ. 2000. Primer3 on the WWW for general users and for biologist programmers. In: Bioinformatics methods and protocols: methods in molecular biology. Humana Press, Totowa, New Jersey, pp 365-386.
26. Seo SH, Webby R, Webster RG. 2004. No apoptotic deaths and different levels of inductions of infl ammatory cytokines in alveolar macrophages infected with infl uenza viruses. Virology 329:270-279.
27. Soos JM, Szente BE. 2003. Type I interferons. In: Thomson AW, Lotze MT eds. The cytokine handbook, vol. 1. London: Academic Press, pp 549-566.
28. SPSS® Statistical Package for Social Science SPSS (1997). Advanced Statistics 7.5. SPSS Inc., Chicago, IL.
29. Taniguchi T, Takaoka A. 2001. A weak signal for strong responses: interferon-α/β revisited. Nature Rev Mol Cell Biol 2:378-386.
30. Taylor MW, Grosse WM, Schaley JE, Sanda C, Wu X, Chien SC, Smith F, Wu TG, Stephens M, Ferris MW, McClintick JN, Jerome RE, Edenberg HJ. 2004. Global effect of PEG-IFN-alpha and ribavirin on gene expression in PBMC in vitro. J Interferon Cytokine Res 24:107-118.
31. Tompkins W. 1999. Immunomodulation and therapeutic effect of the oral use of IFN-α: mechanism of action. J Interferon Cytokine Res 19:817-828.
32. Wattrang E, Wallgren P, Lindberg A, Fossum C. 1998. Signs of infections and reduced immune functions at weaning of conventionally reared and specifi c pathogen free pigs. J Vet Med B 45:7-17.
33. Yasuda K, Fukuoka M, Fujiwara H, Mori T. 1992. Effects of interferon on the steroidogenic functions and proliferation of immature porcine granulosa cells in culture. Biol Reprod 47:931-936.
34. Zhou Y, Lin G, Baarsch MJ, Scamurra RW, Murtaugh MP. 1994. Interleukin-4 suppresses infl ammatory cytokine gene transcription in porcine macrophages. J Leukoc Biol 56:507-513.